Improved proteolytic stability and potent activity against Leishmania infantum trypanothione reductase of α/β-peptide foldamers conjugated to cell-penetrating peptides

The analytical data and overall yields of final α,β,-peptides 5-20 (Table S1), HPLC, HRMS or MALDI-TOF-MS of α,β,-peptide foldamers analogues, and proteolysis stability data are also included. Supplementary data related to this article can be found at https://doi.org/10.1016/j.ejmech.2017.09.032....

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Detalhes bibliográficos
Autores: Lucio, Héctor de, Gamo, Ana María, Ruiz-Santaquiteria, Marta, Castro, Sonia de, Sánchez-Murcia, Pedro A., Toro, Miguel Ángel, Gutiérrez, Kilian Jesús, Gago, Federico, Jiménez- Ruiz, Antonio, Camarasa Rius, María José, Velázquez, Sonsoles
Formato: artículo
Estado:Versión enviada para evaluación y publicación
Fecha de publicación:2017
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/156688
Acesso em linha:http://hdl.handle.net/10261/156688
Access Level:acceso abierto
Palavra-chave:α/β-peptides
Foldamers
Proteolysis
Protein-protein interactions
Trypanothione reductase
Leishmania infantum
Descrição
Resumo:The analytical data and overall yields of final α,β,-peptides 5-20 (Table S1), HPLC, HRMS or MALDI-TOF-MS of α,β,-peptide foldamers analogues, and proteolysis stability data are also included. Supplementary data related to this article can be found at https://doi.org/10.1016/j.ejmech.2017.09.032.

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