New Insights in Therapy for Food Allergy

Food allergy is an increasing problem worldwide, with strict avoidance being classically the only available reliable treatment. The main objective of this review is to cover the latest information about the tools available for the diagnosis and treatment of food allergies. In recent years, many effo...

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Authors: Mayorga, Cristobalina, Palomares, Francisca, Cañas, José A., Pérez-Sánchez, Natalia, Núñez, Rafael, Torres, María José, Gómez, Francisca
Format: article
Publication Date:2021
Country:España
Institution:Instituto de Salud Carlos III (ISCIII)
Repository:Repisalud
Language:English
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/18337
Online Access:http://hdl.handle.net/20.500.12105/18337
Access Level:Open access
Keyword:Food allergy
Specific immunotherapy
Non-specific therapy
Hypoallergens
Nanoparticles
Microbiota
Hipersensibilidad a los alimentos
Inmunoterapia
Nanopartículas
Food Hypersensitivity
Immunoglobulin E
Biological Products
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spelling New Insights in Therapy for Food AllergyMayorga, CristobalinaPalomares, FranciscaCañas, José A.Pérez-Sánchez, NataliaNúñez, RafaelTorres, María JoséGómez, FranciscaFood allergySpecific immunotherapyNon-specific therapyHypoallergensNanoparticlesMicrobiotaHipersensibilidad a los alimentosInmunoterapiaNanopartículasMicrobiotaFood HypersensitivityImmunoglobulin ENanoparticlesMicrobiotaBiological ProductsFood allergy is an increasing problem worldwide, with strict avoidance being classically the only available reliable treatment. The main objective of this review is to cover the latest information about the tools available for the diagnosis and treatment of food allergies. In recent years, many efforts have been made to better understand the humoral and cellular mechanisms involved in food allergy and to improve the strategies for diagnosis and treatment. This review illustrates IgE-mediated food hypersensitivity and provides a current description of the diagnostic strategies and advances in different treatments. Specific immunotherapy, including different routes of administration and new therapeutic approaches, such as hypoallergens and nanoparticles, are discussed in detail. Other treatments, such as biologics and microbiota, are also described. Therefore, we conclude that although important efforts have been made in improving therapies for food allergies, including innovative approaches mainly focusing on efficacy and safety, there is an urgent need to develop a set of basic and clinical results to help in the diagnosis and treatment of food allergies.Multidisciplinary Digital Publishing Institute (MDPI)[Mayorga,C; Palomares,F; Cañas,JA; Núñez,R] Allergy Research Group, Instituto de Investigación Biomédica de Málaga (IBIMA),Málaga, Spain. [Mayorga,C; Pérez-Sánchez,N; Torres,MJ; Gomez,F] Allergy Clinical Unit, Hospital Regional Universitario de Málaga, Málaga, Spain. [Torres,MJ] Medicine Department, Universidad de Málaga-UMA, Málaga, Spain.20242024-02-1920212021-05-1020212021-05-10review articlehttp://purl.org/coar/resource_type/c_dcae04bcVoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articlehttp://hdl.handle.net/20.500.12105/18337reponame:Repisaludinstname:Instituto de Salud Carlos III (ISCIII)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:repisalud.isciii.es:20.500.12105/183372026-06-12T12:43:37Z
dc.title.none.fl_str_mv New Insights in Therapy for Food Allergy
title New Insights in Therapy for Food Allergy
spellingShingle New Insights in Therapy for Food Allergy
Mayorga, Cristobalina
Food allergy
Specific immunotherapy
Non-specific therapy
Hypoallergens
Nanoparticles
Microbiota
Hipersensibilidad a los alimentos
Inmunoterapia
Nanopartículas
Microbiota
Food Hypersensitivity
Immunoglobulin E
Nanoparticles
Microbiota
Biological Products
title_short New Insights in Therapy for Food Allergy
title_full New Insights in Therapy for Food Allergy
title_fullStr New Insights in Therapy for Food Allergy
title_full_unstemmed New Insights in Therapy for Food Allergy
title_sort New Insights in Therapy for Food Allergy
dc.creator.none.fl_str_mv Mayorga, Cristobalina
Palomares, Francisca
Cañas, José A.
Pérez-Sánchez, Natalia
Núñez, Rafael
Torres, María José
Gómez, Francisca
author Mayorga, Cristobalina
author_facet Mayorga, Cristobalina
Palomares, Francisca
Cañas, José A.
Pérez-Sánchez, Natalia
Núñez, Rafael
Torres, María José
Gómez, Francisca
author_role author
author2 Palomares, Francisca
Cañas, José A.
Pérez-Sánchez, Natalia
Núñez, Rafael
Torres, María José
Gómez, Francisca
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv [Mayorga,C; Palomares,F; Cañas,JA; Núñez,R] Allergy Research Group, Instituto de Investigación Biomédica de Málaga (IBIMA),Málaga, Spain. [Mayorga,C; Pérez-Sánchez,N; Torres,MJ; Gomez,F] Allergy Clinical Unit, Hospital Regional Universitario de Málaga, Málaga, Spain. [Torres,MJ] Medicine Department, Universidad de Málaga-UMA, Málaga, Spain.
dc.subject.none.fl_str_mv Food allergy
Specific immunotherapy
Non-specific therapy
Hypoallergens
Nanoparticles
Microbiota
Hipersensibilidad a los alimentos
Inmunoterapia
Nanopartículas
Microbiota
Food Hypersensitivity
Immunoglobulin E
Nanoparticles
Microbiota
Biological Products
topic Food allergy
Specific immunotherapy
Non-specific therapy
Hypoallergens
Nanoparticles
Microbiota
Hipersensibilidad a los alimentos
Inmunoterapia
Nanopartículas
Microbiota
Food Hypersensitivity
Immunoglobulin E
Nanoparticles
Microbiota
Biological Products
description Food allergy is an increasing problem worldwide, with strict avoidance being classically the only available reliable treatment. The main objective of this review is to cover the latest information about the tools available for the diagnosis and treatment of food allergies. In recent years, many efforts have been made to better understand the humoral and cellular mechanisms involved in food allergy and to improve the strategies for diagnosis and treatment. This review illustrates IgE-mediated food hypersensitivity and provides a current description of the diagnostic strategies and advances in different treatments. Specific immunotherapy, including different routes of administration and new therapeutic approaches, such as hypoallergens and nanoparticles, are discussed in detail. Other treatments, such as biologics and microbiota, are also described. Therefore, we conclude that although important efforts have been made in improving therapies for food allergies, including innovative approaches mainly focusing on efficacy and safety, there is an urgent need to develop a set of basic and clinical results to help in the diagnosis and treatment of food allergies.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-05-10
2021
2021-05-10
2024
2024-02-19
dc.type.none.fl_str_mv review article
http://purl.org/coar/resource_type/c_dcae04bc
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12105/18337
url http://hdl.handle.net/20.500.12105/18337
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
dc.source.none.fl_str_mv reponame:Repisalud
instname:Instituto de Salud Carlos III (ISCIII)
instname_str Instituto de Salud Carlos III (ISCIII)
reponame_str Repisalud
collection Repisalud
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869423304732835840
score 15,811543

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