Development of topical ophthalmic formulations for fungal keratitis treatment

In the present thesis, different topical-ophthalmic formulations of antifungals and cyclodextrins were developed for the treatment of fungal keratitis. In addition, the safety and permanence on the ocular surface of different cyclodextrins were evaluated in order to know their behavior in the eye an...

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Detalhes bibliográficos
Autor: Díaz Tomé, Victoria
Formato: tesis doctoral
Fecha de publicación:2023
País:España
Recursos:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:minerva.usc.gal:10347/30562
Acesso em linha:http://hdl.handle.net/10347/30562
Access Level:acceso abierto
Palavra-chave:Materias::Investigación::32 Ciencias médicas::3209 Farmacología::320902 Composición de medicamentos
Materias::Investigación::32 Ciencias médicas::3209 Farmacología::320903 Evaluación de medicamentos
Materias::Investigación::32 Ciencias médicas::3209 Farmacología::320908 Preparación de medicamentos
Descrição
Resumo:In the present thesis, different topical-ophthalmic formulations of antifungals and cyclodextrins were developed for the treatment of fungal keratitis. In addition, the safety and permanence on the ocular surface of different cyclodextrins were evaluated in order to know their behavior in the eye and to optimize their use in the development of new ophthalmic formulations.