UWB-modulated microwave imaging for human brain functional monitoring

Morphological microwave imaging has shown interesting results on reconstructing biological objects inside the human body, and these parameters represent their actual biological condition, but not their biological activity. In this paper, we propose a novel microwave technique to locate the low-frequ...

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Detalles Bibliográficos
Autores: Akazzim, Youness|||0000-0002-7957-4044, Jofre Cruanyes, Marc|||0000-0002-8912-6595, El Mrabet, Otman, Romeu Robert, Jordi|||0000-0003-0197-5961, Jofre Roca, Lluís|||0000-0002-0547-901X
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/386985
Acceso en línea:https://hdl.handle.net/2117/386985
https://dx.doi.org/10.3390/s23094374
Access Level:acceso abierto
Palabra clave:Parkinson's disease
Microwave imaging
UWB microwave imaging
Action potential
Microtag
UWB microwave modulation
Functional imaging
Parkinson, Malaltia de
Imatgeria mèdica
Àrees temàtiques de la UPC::Enginyeria de la telecomunicació::Processament del senyal
Descripción
Sumario:Morphological microwave imaging has shown interesting results on reconstructing biological objects inside the human body, and these parameters represent their actual biological condition, but not their biological activity. In this paper, we propose a novel microwave technique to locate the low-frequency (f≃1 kHz) -modulated signals produced by a microtag mimicking an action potential and proved it in a cylindrical phantom of the brain region. A set of two combined UWB microwave applicators, operating in the 0.5 to 2.5 GHz frequency band and producing a nsec interrogation pulse, is able to focus its radiated field into a small region of the brain containing the microtag with a modulated photodiode. The illuminating UWB microwave field was first modulated by the low-frequency (f≃1 kHz) electrical signal produced by the photodiode, inducing modulated microwave currents into the microtag that reradiating back towards the focusing applicators. At the receiving end, the low-frequency (f≃1 kHz) -modulated signal was first extracted from the full set of the backscattered signals, then focused into the region of interest and spatially represented in the corresponding region of the brain, resulting in a spatial resolution of the images in the order of 10 mm.