Recovery in patients with major depressive disorder (MDD): results of a 6-month, multinational, observational study.

Not all individuals treated for major depressive disorder (MDD) achieve recovery. This observational study examined the recovery rates in MDD patients and the patient characteristics associated with achieving recovery in a naturalistic clinical setting. Recovery was defined as having both clinical a...

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Detalles Bibliográficos
Autores: Novick D, Montgomery W, Vorstenbosch E, Moneta MV, Dueñas H, Haro JM
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Institución:Fundació Sant Joan de Déu
Repositorio:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
OAI Identifier:oai:fsjd.fundanetsuite.com:p13249
Acceso en línea:https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=13249
Access Level:acceso abierto
Palabra clave:clinical remission
course of illness
disability
functional impairment
predictors
remission
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spelling Recovery in patients with major depressive disorder (MDD): results of a 6-month, multinational, observational study.Novick DMontgomery WVorstenbosch EMoneta MVDueñas HHaro JMclinical remissioncourse of illnessdisabilityfunctional impairmentpredictorsremissionNot all individuals treated for major depressive disorder (MDD) achieve recovery. This observational study examined the recovery rates in MDD patients and the patient characteristics associated with achieving recovery in a naturalistic clinical setting. Recovery was defined as having both clinical and functional remission. Data for this post hoc analysis were taken from a 24-week prospective, observational study that involved 1,549 MDD patients. Clinical remission was assessed using the 16-item Quick Inventory of Depressive Symptomatology Self-Report and functional remission through the Sheehan Disability Scale and no days of reduced productivity in the previous week. Generalized estimating equation regression models were used to examine the baseline factors associated with recovery during follow-up. Clinical and functional remission was achieved in 70.6% and 56.1% of the MDD patients, respectively. MDD patients who achieved recovery (52.1%) were significantly less likely to have impaired levels of functioning, concurrent medical or psychiatric conditions, low levels of education, or nonadherence to therapy at follow-up. The level of functioning during the index episode seems to be a better predictor of recovery than symptom severity. Therefore, the level of functioning should be considered while determining recovery from depression.DOVE MEDICAL PRESS LTD2017info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=13249Patient Preference and AdherenceISSN: 1177889Xreponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déuinstname:Fundació Sant Joan de DéuInglésinfo:eu-repo/semantics/openAccessoai:fsjd.fundanetsuite.com:p132492026-05-27T12:37:41Z
dc.title.none.fl_str_mv Recovery in patients with major depressive disorder (MDD): results of a 6-month, multinational, observational study.
title Recovery in patients with major depressive disorder (MDD): results of a 6-month, multinational, observational study.
spellingShingle Recovery in patients with major depressive disorder (MDD): results of a 6-month, multinational, observational study.
Novick D
clinical remission
course of illness
disability
functional impairment
predictors
remission
title_short Recovery in patients with major depressive disorder (MDD): results of a 6-month, multinational, observational study.
title_full Recovery in patients with major depressive disorder (MDD): results of a 6-month, multinational, observational study.
title_fullStr Recovery in patients with major depressive disorder (MDD): results of a 6-month, multinational, observational study.
title_full_unstemmed Recovery in patients with major depressive disorder (MDD): results of a 6-month, multinational, observational study.
title_sort Recovery in patients with major depressive disorder (MDD): results of a 6-month, multinational, observational study.
dc.creator.none.fl_str_mv Novick D
Montgomery W
Vorstenbosch E
Moneta MV
Dueñas H
Haro JM
author Novick D
author_facet Novick D
Montgomery W
Vorstenbosch E
Moneta MV
Dueñas H
Haro JM
author_role author
author2 Montgomery W
Vorstenbosch E
Moneta MV
Dueñas H
Haro JM
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv clinical remission
course of illness
disability
functional impairment
predictors
remission
topic clinical remission
course of illness
disability
functional impairment
predictors
remission
description Not all individuals treated for major depressive disorder (MDD) achieve recovery. This observational study examined the recovery rates in MDD patients and the patient characteristics associated with achieving recovery in a naturalistic clinical setting. Recovery was defined as having both clinical and functional remission. Data for this post hoc analysis were taken from a 24-week prospective, observational study that involved 1,549 MDD patients. Clinical remission was assessed using the 16-item Quick Inventory of Depressive Symptomatology Self-Report and functional remission through the Sheehan Disability Scale and no days of reduced productivity in the previous week. Generalized estimating equation regression models were used to examine the baseline factors associated with recovery during follow-up. Clinical and functional remission was achieved in 70.6% and 56.1% of the MDD patients, respectively. MDD patients who achieved recovery (52.1%) were significantly less likely to have impaired levels of functioning, concurrent medical or psychiatric conditions, low levels of education, or nonadherence to therapy at follow-up. The level of functioning during the index episode seems to be a better predictor of recovery than symptom severity. Therefore, the level of functioning should be considered while determining recovery from depression.
publishDate 2017
dc.date.none.fl_str_mv 2017
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=13249
url https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=13249
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv DOVE MEDICAL PRESS LTD
publisher.none.fl_str_mv DOVE MEDICAL PRESS LTD
dc.source.none.fl_str_mv Patient Preference and Adherence
ISSN: 1177889X
reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname:Fundació Sant Joan de Déu
instname_str Fundació Sant Joan de Déu
reponame_str r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
collection r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
repository.name.fl_str_mv
repository.mail.fl_str_mv
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