Gold-based nanoparticles on amino-functionalized mesoporous silica supports as nanozymes for glucose oxidation

This article belongs to the Special Issue State of the Art and Future Trends in Nanostructured Biocatalysis.

Detalles Bibliográficos
Autores: Ortega-Liébana, M. Carmen, Bonet-Aleta, Javier, Hueso, José L., Santamaría, Jesús
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/218946
Acceso en línea:http://hdl.handle.net/10261/218946
Access Level:acceso abierto
Palabra clave:Nanozymes
Surface functionalization
Enzyme-mimicking
Glucose oxidation
Mesoporous silica
Gold
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spelling Gold-based nanoparticles on amino-functionalized mesoporous silica supports as nanozymes for glucose oxidationOrtega-Liébana, M. CarmenBonet-Aleta, JavierHueso, José L.Santamaría, JesúsNanozymesSurface functionalizationEnzyme-mimickingGlucose oxidationMesoporous silicaGoldThis article belongs to the Special Issue State of the Art and Future Trends in Nanostructured Biocatalysis.The transformation of glucose represents a topic of great interest at different levels. In the first place, glucose is currently conceived as a green feedstock for the sustainable production of chemicals. Secondly, the depletion of glucose at the cellular level is currently envisioned as a promising strategy to treat and alter the erratic metabolism of tumoral cells. The use of natural enzymes offers multiple advantages in terms of specificity towards the glucose substrate but may lack sufficient robustness and recyclability beyond the optimal operating conditions of these natural systems. In the present work, we have evaluated the potential use of an inorganic based nanohybrid containing gold nanoparticles supported onto ordered mesoporous supports. We have performed different assays that corroborate the enzyme-mimicking response of these inorganic surrogates towards the selective conversion of glucose into gluconic acid and hydrogen peroxide. Moreover, we conclude that these enzyme-like mimicking surrogates can operate at different pH ranges and under mild reaction conditions, can be recycled multiple times and maintain excellent catalytic response in comparison with other gold-based catalysts.Financial support from the European Research Council (ERC Advanced Grant CADENCE number 742684) is gratefully acknowledged. The TEM measurements were conducted at the Laboratorio de Microscopias Avanzadas, Instituto de Nanociencia de Aragon, Universidad de Zaragoza, Spain. The synthesis of materials has been performed by the Platform of Production of Biomaterials and Nanoparticles of the NANOBIOSIS ICTS, more specifically by the Nanoparticle Synthesis Unit of the CIBER in BioEngineering, Biomaterials & Nanomedicine (CIBER-BBN). J.B-A. acknowledges the Spanish Government for an FPU predoctoral contract.Peer reviewedMultidisciplinary Digital Publishing InstituteEuropean CommissionEuropean Research CouncilMinisterio de Economía y Competitividad (España)Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202020202020info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/218946reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/EC/H2020/742684https://doi.org/10.3390/catal10030333Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/2189462026-05-22T06:33:51Z
dc.title.none.fl_str_mv Gold-based nanoparticles on amino-functionalized mesoporous silica supports as nanozymes for glucose oxidation
title Gold-based nanoparticles on amino-functionalized mesoporous silica supports as nanozymes for glucose oxidation
spellingShingle Gold-based nanoparticles on amino-functionalized mesoporous silica supports as nanozymes for glucose oxidation
Ortega-Liébana, M. Carmen
Nanozymes
Surface functionalization
Enzyme-mimicking
Glucose oxidation
Mesoporous silica
Gold
title_short Gold-based nanoparticles on amino-functionalized mesoporous silica supports as nanozymes for glucose oxidation
title_full Gold-based nanoparticles on amino-functionalized mesoporous silica supports as nanozymes for glucose oxidation
title_fullStr Gold-based nanoparticles on amino-functionalized mesoporous silica supports as nanozymes for glucose oxidation
title_full_unstemmed Gold-based nanoparticles on amino-functionalized mesoporous silica supports as nanozymes for glucose oxidation
title_sort Gold-based nanoparticles on amino-functionalized mesoporous silica supports as nanozymes for glucose oxidation
dc.creator.none.fl_str_mv Ortega-Liébana, M. Carmen
Bonet-Aleta, Javier
Hueso, José L.
Santamaría, Jesús
author Ortega-Liébana, M. Carmen
author_facet Ortega-Liébana, M. Carmen
Bonet-Aleta, Javier
Hueso, José L.
Santamaría, Jesús
author_role author
author2 Bonet-Aleta, Javier
Hueso, José L.
Santamaría, Jesús
author2_role author
author
author
dc.contributor.none.fl_str_mv European Commission
European Research Council
Ministerio de Economía y Competitividad (España)
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Nanozymes
Surface functionalization
Enzyme-mimicking
Glucose oxidation
Mesoporous silica
Gold
topic Nanozymes
Surface functionalization
Enzyme-mimicking
Glucose oxidation
Mesoporous silica
Gold
description This article belongs to the Special Issue State of the Art and Future Trends in Nanostructured Biocatalysis.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020
2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/218946
url http://hdl.handle.net/10261/218946
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/EC/H2020/742684
https://doi.org/10.3390/catal10030333
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.811543

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