Semaphorin 3C exacerbates liver fibrosis.

Chronic liver disease is a growing epidemic, leading to fibrosis and cirrhosis. TGF-ß is the pivotal profibrogenic cytokine that activates HSC, yet other molecules can modulate TGF-ß signaling during liver fibrosis. Expression of the axon guidance molecules semaphorins (SEMAs), which signal through...

Descripción completa

Detalles Bibliográficos
Autores: De Angelis Rigotti F, Wiedmann L, Hubert MO, Vacca M, Hasan SS, Moll I, Carvajal S, Jiménez W, Starostecka M, Billeter AT, Müller-Stich B, Wolff G, Ekim-Üstünel B, Herzig S, Fandos-Ramo C, Krätzner R, Reich M, Keitel-Anselmino V, Heikenwälder M, Mogler C, Fischer A, Rodriguez-Vita J
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Centro de Investigación Principe Felipe (CIPF)
Repositorio:r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
OAI Identifier:oai:cipf.fundanetsuite.com:p4088
Acceso en línea:https://cipf.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4088
Access Level:acceso abierto
id ES_eb0f33ca8d1be77ec615ca3ebf31d2fa
oai_identifier_str oai:cipf.fundanetsuite.com:p4088
network_acronym_str ES
network_name_str España
repository_id_str
spelling Semaphorin 3C exacerbates liver fibrosis.De Angelis Rigotti FWiedmann LHubert MOVacca MHasan SSMoll ICarvajal SJiménez WStarostecka MBilleter ATMüller-Stich BWolff GEkim-Üstünel BHerzig SFandos-Ramo CKrätzner RReich MKeitel-Anselmino VHeikenwälder MMogler CFischer ARodriguez-Vita JChronic liver disease is a growing epidemic, leading to fibrosis and cirrhosis. TGF-ß is the pivotal profibrogenic cytokine that activates HSC, yet other molecules can modulate TGF-ß signaling during liver fibrosis. Expression of the axon guidance molecules semaphorins (SEMAs), which signal through plexins and neuropilins (NRPs), have been associated with liver fibrosis in HBV-induced chronic hepatitis. This study aims at determining their function in the regulation of HSCs.LIPPINCOTT WILLIAMS & WILKINS2023info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://cipf.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4088HEPATOLOGYISSN: 02709139ISSNe: 15273350reponame:r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)instname:Centro de Investigación Principe Felipe (CIPF)Inglésinfo:eu-repo/semantics/openAccessoai:cipf.fundanetsuite.com:p40882026-06-17T11:19:47Z
dc.title.none.fl_str_mv Semaphorin 3C exacerbates liver fibrosis.
title Semaphorin 3C exacerbates liver fibrosis.
spellingShingle Semaphorin 3C exacerbates liver fibrosis.
De Angelis Rigotti F
title_short Semaphorin 3C exacerbates liver fibrosis.
title_full Semaphorin 3C exacerbates liver fibrosis.
title_fullStr Semaphorin 3C exacerbates liver fibrosis.
title_full_unstemmed Semaphorin 3C exacerbates liver fibrosis.
title_sort Semaphorin 3C exacerbates liver fibrosis.
dc.creator.none.fl_str_mv De Angelis Rigotti F
Wiedmann L
Hubert MO
Vacca M
Hasan SS
Moll I
Carvajal S
Jiménez W
Starostecka M
Billeter AT
Müller-Stich B
Wolff G
Ekim-Üstünel B
Herzig S
Fandos-Ramo C
Krätzner R
Reich M
Keitel-Anselmino V
Heikenwälder M
Mogler C
Fischer A
Rodriguez-Vita J
author De Angelis Rigotti F
author_facet De Angelis Rigotti F
Wiedmann L
Hubert MO
Vacca M
Hasan SS
Moll I
Carvajal S
Jiménez W
Starostecka M
Billeter AT
Müller-Stich B
Wolff G
Ekim-Üstünel B
Herzig S
Fandos-Ramo C
Krätzner R
Reich M
Keitel-Anselmino V
Heikenwälder M
Mogler C
Fischer A
Rodriguez-Vita J
author_role author
author2 Wiedmann L
Hubert MO
Vacca M
Hasan SS
Moll I
Carvajal S
Jiménez W
Starostecka M
Billeter AT
Müller-Stich B
Wolff G
Ekim-Üstünel B
Herzig S
Fandos-Ramo C
Krätzner R
Reich M
Keitel-Anselmino V
Heikenwälder M
Mogler C
Fischer A
Rodriguez-Vita J
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
description Chronic liver disease is a growing epidemic, leading to fibrosis and cirrhosis. TGF-ß is the pivotal profibrogenic cytokine that activates HSC, yet other molecules can modulate TGF-ß signaling during liver fibrosis. Expression of the axon guidance molecules semaphorins (SEMAs), which signal through plexins and neuropilins (NRPs), have been associated with liver fibrosis in HBV-induced chronic hepatitis. This study aims at determining their function in the regulation of HSCs.
publishDate 2023
dc.date.none.fl_str_mv 2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://cipf.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4088
url https://cipf.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4088
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv LIPPINCOTT WILLIAMS & WILKINS
publisher.none.fl_str_mv LIPPINCOTT WILLIAMS & WILKINS
dc.source.none.fl_str_mv HEPATOLOGY
ISSN: 02709139
ISSNe: 15273350
reponame:r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
instname:Centro de Investigación Principe Felipe (CIPF)
instname_str Centro de Investigación Principe Felipe (CIPF)
reponame_str r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
collection r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869423194177273856
score 15,81155