Reactivation of hepatitis B in an HIV-infected patient with antibodies against hepatitis B core antigen as the only serological marker

[EN]Presented here is the first report of clinical reactivation of hepatitis B virus (HBV) in an HIV-infected patient who previously had anti-HBc as the only serological marker of past infection (anti-HBc alone). Reactivation occurred after lamivudine was removed from the patient’s antiretroviral tr...

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Bibliographic Details
Authors: Chamorro Fernández, Antonio Javier, Casado, J. L., Bellido, D., Moreno Guillén, Santiago
Format: article
Status:Published version
Publication Date:2005
Country:España
Institution:Universidad de Salamanca (USAL)
Repository:GREDOS. Repositorio Institucional de la Universidad de Salamanca
OAI Identifier:oai:gredos.usal.es:10366/154040
Online Access:http://hdl.handle.net/10366/154040
Access Level:Embargoed access
Keyword:Hepatitis B
HIV Antibodies
Hepatitis B e Antigens
hepatitis B
antigenos E de la hepatitis B
anticuerpos VIH
Description
Summary:[EN]Presented here is the first report of clinical reactivation of hepatitis B virus (HBV) in an HIV-infected patient who previously had anti-HBc as the only serological marker of past infection (anti-HBc alone). Reactivation occurred after lamivudine was removed from the patient’s antiretroviral treatment regimen due to lack of virological response. HIV-infected patients frequently present anti-HBc alone, and in some cases this serological profile is associated with occult HBV infection. The current case demonstrates the importance of ruling out the possibility of occult infection in this patient group