Synthesis of oxadendralenes by thermal oxy-cope type rearrangement of bis(α-Hydroxyallenes)
We report the direct and selective synthesis of oxadendralenes starting from readily available bis(α-hydroxyallenes). The designed sequence involves a hitherto unknown oxy-Cope rearrangement of allenols by supplying a site for the migration of the 1,2-diene moiety. Moreover, the so-prepared oxadendr...
| Autores: | , , |
|---|---|
| Tipo de recurso: | artículo |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Universidad Complutense de Madrid (UCM) |
| Repositorio: | Docta Complutense |
| Idioma: | inglés |
| OAI Identifier: | oai:docta.ucm.es:20.500.14352/122891 |
| Acceso en línea: | https://hdl.handle.net/20.500.14352/122891 |
| Access Level: | acceso abierto |
| Palabra clave: | 547 Química orgánica (Química) 2306 Química Orgánica |
| Sumario: | We report the direct and selective synthesis of oxadendralenes starting from readily available bis(α-hydroxyallenes). The designed sequence involves a hitherto unknown oxy-Cope rearrangement of allenols by supplying a site for the migration of the 1,2-diene moiety. Moreover, the so-prepared oxadendralenes were converted into valuable polyfunctionalized scaffolds through effective late-stage diversification. |
|---|