Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the PREDIMED study

Background and aims: There is ongoing controversy about the effect of a low to moderate alcohol consumption on atrial fibrillation (AF). Our aim is to assess the association between adherence to a Mediterranean alcohol drinking pattern and AF incidence. Methods and results: A total 6527 out of the 7...

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Detalles Bibliográficos
Autores: Bazal, P., Gea, Alfredo, Martínez-González, Miguel Ángel, 1957-, Salas-Salvadó, Jordi, Asensio, Eva M., Muñoz-Bravo, Carlos, Fiol, Miquel, Muñoz, Miguel Ángel, Lapetra, José, Serra-Majem, Luis, Pinto, Xavier, González, José I., Becerra-Tomás, Nerea, Fitó Colomer, Montserrat, Ros, Emilio, Alonso-Gómez, Ángel, Ruiz-Canela, Miguel
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2019
País:España
Institución:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/43982
Acceso en línea:http://hdl.handle.net/10230/43982
http://dx.doi.org/10.1016/j.numecd.2019.03.007
Access Level:acceso abierto
Palabra clave:Alcohol
Antioxidant
Atrial fibrillation
Mediterranean
Red wine
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spelling Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the PREDIMED studyBazal, P.Gea, AlfredoMartínez-González, Miguel Ángel, 1957-Salas-Salvadó, JordiAsensio, Eva M.Muñoz-Bravo, CarlosFiol, MiquelMuñoz, Miguel ÁngelLapetra, JoséSerra-Majem, LuisPinto, XavierGonzález, José I.Becerra-Tomás, NereaFitó Colomer, MontserratRos, EmilioAlonso-Gómez, ÁngelRuiz-Canela, MiguelAlcoholAntioxidantAtrial fibrillationMediterraneanRed wineBackground and aims: There is ongoing controversy about the effect of a low to moderate alcohol consumption on atrial fibrillation (AF). Our aim is to assess the association between adherence to a Mediterranean alcohol drinking pattern and AF incidence. Methods and results: A total 6527 out of the 7447 participants in the PREDIMED trial met our inclusion criteria. A validated frequency food questionnaire was used to measure alcohol consumption. Participants were classified as non-drinkers, Mediterranean alcohol drinking pattern (MADP) (10-30 g/d in men and 5-15 g/day in women, preferably red wine consumption with low spirits consumption), low-moderate drinking (<30 g/day men y and < 15 g/day women), and heavy drinking. We performed multivariable Cox regression models to estimate hazard ratios (HR) with 95% confidence intervals (95% CI) of incident AF according to alcohol drinking patterns. After a mean follow up of 4.4 years, 241 new incident AF cases were confirmed. Alcohol consumption was not associated to AF incidence among low-moderate drinkers (HR: 0.96; 95%CI: 0.67-1.37), adherents to MADP (HR: 1.15 95%CI: 0.75-1.75), or heavy drinkers (HR: 0.92; 95%CI: 0.53-1.58), compared with non-drinkers. Conclusions: In a high cardiovascular risk adult population, a Mediterranean alcohol consumption pattern (low to moderate red wine consumption) was not associated with an increased incidence of AF.Elsevier20202019info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/43982http://dx.doi.org/10.1016/j.numecd.2019.03.007reponame:Repositorio Digital de la UPFinstname:Universitat Pompeu FabraInglés© Elsevier http://dx.doi.org/10.1016/j.numecd.2019.03.007info:eu-repo/semantics/openAccessoai:repositori.upf.edu:10230/439822026-06-12T07:21:37Z
dc.title.none.fl_str_mv Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the PREDIMED study
title Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the PREDIMED study
spellingShingle Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the PREDIMED study
Bazal, P.
Alcohol
Antioxidant
Atrial fibrillation
Mediterranean
Red wine
title_short Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the PREDIMED study
title_full Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the PREDIMED study
title_fullStr Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the PREDIMED study
title_full_unstemmed Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the PREDIMED study
title_sort Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the PREDIMED study
dc.creator.none.fl_str_mv Bazal, P.
Gea, Alfredo
Martínez-González, Miguel Ángel, 1957-
Salas-Salvadó, Jordi
Asensio, Eva M.
Muñoz-Bravo, Carlos
Fiol, Miquel
Muñoz, Miguel Ángel
Lapetra, José
Serra-Majem, Luis
Pinto, Xavier
González, José I.
Becerra-Tomás, Nerea
Fitó Colomer, Montserrat
Ros, Emilio
Alonso-Gómez, Ángel
Ruiz-Canela, Miguel
author Bazal, P.
author_facet Bazal, P.
Gea, Alfredo
Martínez-González, Miguel Ángel, 1957-
Salas-Salvadó, Jordi
Asensio, Eva M.
Muñoz-Bravo, Carlos
Fiol, Miquel
Muñoz, Miguel Ángel
Lapetra, José
Serra-Majem, Luis
Pinto, Xavier
González, José I.
Becerra-Tomás, Nerea
Fitó Colomer, Montserrat
Ros, Emilio
Alonso-Gómez, Ángel
Ruiz-Canela, Miguel
author_role author
author2 Gea, Alfredo
Martínez-González, Miguel Ángel, 1957-
Salas-Salvadó, Jordi
Asensio, Eva M.
Muñoz-Bravo, Carlos
Fiol, Miquel
Muñoz, Miguel Ángel
Lapetra, José
Serra-Majem, Luis
Pinto, Xavier
González, José I.
Becerra-Tomás, Nerea
Fitó Colomer, Montserrat
Ros, Emilio
Alonso-Gómez, Ángel
Ruiz-Canela, Miguel
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Alcohol

Antioxidant
Atrial fibrillation
Mediterranean
Red wine
topic Alcohol
Antioxidant
Atrial fibrillation
Mediterranean
Red wine
description Background and aims: There is ongoing controversy about the effect of a low to moderate alcohol consumption on atrial fibrillation (AF). Our aim is to assess the association between adherence to a Mediterranean alcohol drinking pattern and AF incidence. Methods and results: A total 6527 out of the 7447 participants in the PREDIMED trial met our inclusion criteria. A validated frequency food questionnaire was used to measure alcohol consumption. Participants were classified as non-drinkers, Mediterranean alcohol drinking pattern (MADP) (10-30 g/d in men and 5-15 g/day in women, preferably red wine consumption with low spirits consumption), low-moderate drinking (<30 g/day men y and < 15 g/day women), and heavy drinking. We performed multivariable Cox regression models to estimate hazard ratios (HR) with 95% confidence intervals (95% CI) of incident AF according to alcohol drinking patterns. After a mean follow up of 4.4 years, 241 new incident AF cases were confirmed. Alcohol consumption was not associated to AF incidence among low-moderate drinkers (HR: 0.96; 95%CI: 0.67-1.37), adherents to MADP (HR: 1.15 95%CI: 0.75-1.75), or heavy drinkers (HR: 0.92; 95%CI: 0.53-1.58), compared with non-drinkers. Conclusions: In a high cardiovascular risk adult population, a Mediterranean alcohol consumption pattern (low to moderate red wine consumption) was not associated with an increased incidence of AF.
publishDate 2019
dc.date.none.fl_str_mv 2019
2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/43982
http://dx.doi.org/10.1016/j.numecd.2019.03.007
url http://hdl.handle.net/10230/43982
http://dx.doi.org/10.1016/j.numecd.2019.03.007
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv © Elsevier http://dx.doi.org/10.1016/j.numecd.2019.03.007
info:eu-repo/semantics/openAccess
rights_invalid_str_mv © Elsevier http://dx.doi.org/10.1016/j.numecd.2019.03.007
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositorio Digital de la UPF
instname:Universitat Pompeu Fabra
instname_str Universitat Pompeu Fabra
reponame_str Repositorio Digital de la UPF
collection Repositorio Digital de la UPF
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.811543

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