Extrahepatic manifestations associated with Chronic Hepatitis C Virus Infection

Chronic hepatitis C virus (HCV) infection has been associated with both organ-specific and systemic autoimmune diseases, with cryoglobulinemia being the most frequent associated disease. Experimental, virologic, and clinical evidence have demon-strated a close association between HCV infection and s...

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Detalhes bibliográficos
Autores: Flores-Chávez, A, Carrión Rodríguez, José Antonio, Forns, Xavier, Ramos-Casals, M.
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Recursos:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/36448
Acesso em linha:http://hdl.handle.net/10230/36448
http://dx.doi.org/10.4321/S1575-06202017000300004
Access Level:acceso abierto
Palavra-chave:Hepatitis C
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spelling Extrahepatic manifestations associated with Chronic Hepatitis C Virus InfectionFlores-Chávez, ACarrión Rodríguez, José AntonioForns, XavierRamos-Casals, M.Hepatitis CChronic hepatitis C virus (HCV) infection has been associated with both organ-specific and systemic autoimmune diseases, with cryoglobulinemia being the most frequent associated disease. Experimental, virologic, and clinical evidence have demon-strated a close association between HCV infection and some systemic autoimmune diseases, especially Sjögren's syndrome, but also rheumatoid arthritis and lupus. A higher prevalence of hematological processes has also been described in patients with HCV infection, including cytopenias and lymphoproliferative disorders (B-cell lymphoma). In addition, patients with chronic HCV infection have a higher frequency of other extrahepatic manifestations including endocrine, metabolic and cardiovascular disorders that may worse the prognosis of patients, along with neuropsychiatric manifestations and general symptoms that have a significant influence on the quality of life of the patient. Direct-acting antiviral therapies (DAAs) that have recently begun to be used are providing the opportunity to effectively cure chronic HCV infection and reduce the burden of both hepatic and extrahepatic complications.Sociedad Española de Sanidad Penitenciaria201920192017info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/36448http://dx.doi.org/10.4321/S1575-06202017000300004reponame:Repositorio Digital de la UPFinstname:Universitat Pompeu FabraInglésRevista Española de Sanidad Penitenciaria. 2017 Dec;19(3):87-97La Revista Española de Sanidad Penitenciaria es una revista Open Access, lo que quiere decir que todo su contenido es accesible libremente sin cargo para el usuario o su institución. Los usuarios están autorizados a leer, descargar, copiar, distribuir, imprimir, buscar o enlazar a los textos completos de los artículos de esta revista sin permiso previo del editor o del autor, de acuerdo con la definición BOAI de open access. La reutilización de los trabajos puede hacerse en los términos que diga la licencia Creative Commons Reconocimiento-NoComercial-SinObraDerivada 3.0 Unported License.https://creativecommons.org/licenses/by-nc-nd/3.0/deed.es_ESinfo:eu-repo/semantics/openAccessoai:repositori.upf.edu:10230/364482026-06-12T07:21:37Z
dc.title.none.fl_str_mv Extrahepatic manifestations associated with Chronic Hepatitis C Virus Infection
title Extrahepatic manifestations associated with Chronic Hepatitis C Virus Infection
spellingShingle Extrahepatic manifestations associated with Chronic Hepatitis C Virus Infection
Flores-Chávez, A
Hepatitis C
title_short Extrahepatic manifestations associated with Chronic Hepatitis C Virus Infection
title_full Extrahepatic manifestations associated with Chronic Hepatitis C Virus Infection
title_fullStr Extrahepatic manifestations associated with Chronic Hepatitis C Virus Infection
title_full_unstemmed Extrahepatic manifestations associated with Chronic Hepatitis C Virus Infection
title_sort Extrahepatic manifestations associated with Chronic Hepatitis C Virus Infection
dc.creator.none.fl_str_mv Flores-Chávez, A
Carrión Rodríguez, José Antonio
Forns, Xavier
Ramos-Casals, M.
author Flores-Chávez, A
author_facet Flores-Chávez, A
Carrión Rodríguez, José Antonio
Forns, Xavier
Ramos-Casals, M.
author_role author
author2 Carrión Rodríguez, José Antonio
Forns, Xavier
Ramos-Casals, M.
author2_role author
author
author
dc.subject.none.fl_str_mv Hepatitis C
topic Hepatitis C
description Chronic hepatitis C virus (HCV) infection has been associated with both organ-specific and systemic autoimmune diseases, with cryoglobulinemia being the most frequent associated disease. Experimental, virologic, and clinical evidence have demon-strated a close association between HCV infection and some systemic autoimmune diseases, especially Sjögren's syndrome, but also rheumatoid arthritis and lupus. A higher prevalence of hematological processes has also been described in patients with HCV infection, including cytopenias and lymphoproliferative disorders (B-cell lymphoma). In addition, patients with chronic HCV infection have a higher frequency of other extrahepatic manifestations including endocrine, metabolic and cardiovascular disorders that may worse the prognosis of patients, along with neuropsychiatric manifestations and general symptoms that have a significant influence on the quality of life of the patient. Direct-acting antiviral therapies (DAAs) that have recently begun to be used are providing the opportunity to effectively cure chronic HCV infection and reduce the burden of both hepatic and extrahepatic complications.
publishDate 2017
dc.date.none.fl_str_mv 2017
2019
2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/36448
http://dx.doi.org/10.4321/S1575-06202017000300004
url http://hdl.handle.net/10230/36448
http://dx.doi.org/10.4321/S1575-06202017000300004
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Revista Española de Sanidad Penitenciaria. 2017 Dec;19(3):87-97
dc.rights.none.fl_str_mv https://creativecommons.org/licenses/by-nc-nd/3.0/deed.es_ES
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/3.0/deed.es_ES
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Sociedad Española de Sanidad Penitenciaria
publisher.none.fl_str_mv Sociedad Española de Sanidad Penitenciaria
dc.source.none.fl_str_mv reponame:Repositorio Digital de la UPF
instname:Universitat Pompeu Fabra
instname_str Universitat Pompeu Fabra
reponame_str Repositorio Digital de la UPF
collection Repositorio Digital de la UPF
repository.name.fl_str_mv
repository.mail.fl_str_mv
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