Regulation of translation initiation under biotic and abiotic stresses

Plants have developed versatile strategies to deal with the great variety of challenging conditions they are exposed to. Among them, the regulation of translation is a common target to finely modulate gene expression both under biotic and abiotic stress situations. Upon environmental challenges, tra...

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Detalles Bibliográficos
Autores: Echevarría Zomeño, S., Yángüez, E., Fernández-Bautista, N., Castro-Sanz, Ana B., Ferrando, Alejandro, Castellano Moreno, María Mar
Tipo de recurso: artículo
Fecha de publicación:2013
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/291720
Acceso en línea:http://hdl.handle.net/10261/291720
Access Level:acceso abierto
Palabra clave:Regulation of translation: EIF4E
EIF2α
Plant abiotic stress
IRES
CIRES
CITES
Cap-dependent enhancers
Descripción
Sumario:Plants have developed versatile strategies to deal with the great variety of challenging conditions they are exposed to. Among them, the regulation of translation is a common target to finely modulate gene expression both under biotic and abiotic stress situations. Upon environmental challenges, translation is regulated to reduce the consumption of energy and to selectively synthesize proteins involved in the proper establishment of the tolerance response. In the case of viral infections, the situation is more complex, as viruses have evolved unconventional mechanisms to regulate translation in order to ensure the production of the viral encoded proteins using the plant machinery. Although the final purpose is different, in some cases, both plants and viruses share common mechanisms to modulate translation. In others, the mechanisms leading to the control of translation are viral or stress-specific. In this paper, we review the different mechanisms involved in the regulation of translation initiation under virus infection and under environmental stress in plants. In addition, we describe the main features within the viral RNAs and the cellular mRNAs that promote their selective translation in plants undergoing biotic and abiotic stress situations. © 2013 by the authors; licensee MDPI, Basel, Switzerland.