PPARß/d prevents inflammation and fibrosis during diabetic cardiomyopathy

Diabetic cardiomyopathy (DCM) is a specific type of myocardial disease that often develops in patients suffering from diabetes, which has become the foremost cause of death among them. It is an insidious multifactorial disease caused by complex and partially unknown mechanisms that include metabolic...

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Autores: Rostami A, Palomer X, Pizarro-Delgado J, Barroso E, Valenzuela-Alcaraz B, Crispi F, Nistal JF, Hurlé MA, García R, Wahli W, Vázquez-Carrera M
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Fundació Sant Joan de Déu
Repositorio:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
OAI Identifier:oai:fsjd.fundanetsuite.com:p27208
Acceso en línea:https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=27208
Access Level:acceso abierto
Palabra clave:Activator protein-1 (AP-1)
Diabetic cardiomyopathy
Fibrosis
Inflammation
Mitogen-activated protein kinases (MAPK)
Nuclear factor kappa B (NF-kappa B)
Peroxisome proliferator-activated receptor
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spelling PPARß/d prevents inflammation and fibrosis during diabetic cardiomyopathyRostami APalomer XPizarro-Delgado JBarroso EValenzuela-Alcaraz BCrispi FNistal JFHurlé MAGarcía RWahli WVázquez-Carrera MActivator protein-1 (AP-1)Diabetic cardiomyopathyFibrosisInflammationMitogen-activated protein kinases (MAPK)Nuclear factor kappa B (NF-kappa B)Peroxisome proliferator-activated receptorDiabetic cardiomyopathy (DCM) is a specific type of myocardial disease that often develops in patients suffering from diabetes, which has become the foremost cause of death among them. It is an insidious multifactorial disease caused by complex and partially unknown mechanisms that include metabolic dysregulation, local inflammation, fibrosis, and cardiomyocyte apoptosis. Despite its severity and poor prognosis, it often goes undiagnosed, and there are currently no approved specific drugs to prevent or even treat it. Peroxisome proliferator-activated receptor (PPAR)beta/delta is a key metabolic regulator that has been proposed as a potentialACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD2024info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=27208PHARMACOLOGICAL RESEARCHISSN: 10436618ISSNe: 10961186reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déuinstname:Fundació Sant Joan de DéuInglésinfo:eu-repo/semantics/openAccessoai:fsjd.fundanetsuite.com:p272082026-05-27T12:37:41Z
dc.title.none.fl_str_mv PPARß/d prevents inflammation and fibrosis during diabetic cardiomyopathy
title PPARß/d prevents inflammation and fibrosis during diabetic cardiomyopathy
spellingShingle PPARß/d prevents inflammation and fibrosis during diabetic cardiomyopathy
Rostami A
Activator protein-1 (AP-1)
Diabetic cardiomyopathy
Fibrosis
Inflammation
Mitogen-activated protein kinases (MAPK)
Nuclear factor kappa B (NF-kappa B)
Peroxisome proliferator-activated receptor
title_short PPARß/d prevents inflammation and fibrosis during diabetic cardiomyopathy
title_full PPARß/d prevents inflammation and fibrosis during diabetic cardiomyopathy
title_fullStr PPARß/d prevents inflammation and fibrosis during diabetic cardiomyopathy
title_full_unstemmed PPARß/d prevents inflammation and fibrosis during diabetic cardiomyopathy
title_sort PPARß/d prevents inflammation and fibrosis during diabetic cardiomyopathy
dc.creator.none.fl_str_mv Rostami A
Palomer X
Pizarro-Delgado J
Barroso E
Valenzuela-Alcaraz B
Crispi F
Nistal JF
Hurlé MA
García R
Wahli W
Vázquez-Carrera M
author Rostami A
author_facet Rostami A
Palomer X
Pizarro-Delgado J
Barroso E
Valenzuela-Alcaraz B
Crispi F
Nistal JF
Hurlé MA
García R
Wahli W
Vázquez-Carrera M
author_role author
author2 Palomer X
Pizarro-Delgado J
Barroso E
Valenzuela-Alcaraz B
Crispi F
Nistal JF
Hurlé MA
García R
Wahli W
Vázquez-Carrera M
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Activator protein-1 (AP-1)
Diabetic cardiomyopathy
Fibrosis
Inflammation
Mitogen-activated protein kinases (MAPK)
Nuclear factor kappa B (NF-kappa B)
Peroxisome proliferator-activated receptor
topic Activator protein-1 (AP-1)
Diabetic cardiomyopathy
Fibrosis
Inflammation
Mitogen-activated protein kinases (MAPK)
Nuclear factor kappa B (NF-kappa B)
Peroxisome proliferator-activated receptor
description Diabetic cardiomyopathy (DCM) is a specific type of myocardial disease that often develops in patients suffering from diabetes, which has become the foremost cause of death among them. It is an insidious multifactorial disease caused by complex and partially unknown mechanisms that include metabolic dysregulation, local inflammation, fibrosis, and cardiomyocyte apoptosis. Despite its severity and poor prognosis, it often goes undiagnosed, and there are currently no approved specific drugs to prevent or even treat it. Peroxisome proliferator-activated receptor (PPAR)beta/delta is a key metabolic regulator that has been proposed as a potential
publishDate 2024
dc.date.none.fl_str_mv 2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=27208
url https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=27208
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
publisher.none.fl_str_mv ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
dc.source.none.fl_str_mv PHARMACOLOGICAL RESEARCH
ISSN: 10436618
ISSNe: 10961186
reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname:Fundació Sant Joan de Déu
instname_str Fundació Sant Joan de Déu
reponame_str r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
collection r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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