Measuring quantitative proteomic distance between Spanish beef breeds

Estimates of quantitative proteomic distance between populations have not been reported to date. Here, quantitative proteomic distances between three Spanish bovine breeds (Asturiana de los Valles, AV; Retinta, RE; and Rubia Gallega, RG) were estimated from two-dimensional electrophoresis profiles o...

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Detalles Bibliográficos
Autores: Rodríguez Vázquez, Raquel, Mato Montero, Ariadna, López-Pedrouso, María, Franco Ruiz, Daniel, Sentandreu Vicente, Miguel Ángel, Zapata Babío, José Carlos
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:minerva.usc.gal:10347/46146
Acceso en línea:https://hdl.handle.net/10347/46146
Access Level:acceso abierto
Palabra clave:Meat proteomics
Population proteomics
Proteomic distance measures
QD measure
Beef tenderness biomarkers
Beef authenticity biomarkers
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spelling Measuring quantitative proteomic distance between Spanish beef breedsRodríguez Vázquez, RaquelMato Montero, AriadnaLópez-Pedrouso, MaríaFranco Ruiz, DanielSentandreu Vicente, Miguel ÁngelZapata Babío, José CarlosMeat proteomicsPopulation proteomicsProteomic distance measuresQD measureBeef tenderness biomarkersBeef authenticity biomarkersEstimates of quantitative proteomic distance between populations have not been reported to date. Here, quantitative proteomic distances between three Spanish bovine breeds (Asturiana de los Valles, AV; Retinta, RE; and Rubia Gallega, RG) were estimated from two-dimensional electrophoresis profiles of meat samples of longissimus thoracis muscle at 2 h post-mortem. Statistically significant distances were detected between AV/RG and the most genetically different RE breed, using the novel QD measure of quantitative proteomic distance. In total, 18 differentially abundant myofibrillar and sarcoplasmic proteins/isoforms contributing to proteomic distances between breeds were confidently identified by tandem mass spectrometry. The fast skeletal myosin regulatory light chain 2 followed by other five interacting proteins exhibited the most pronounced relative change between breeds. In addition, most differentially represented proteins could be associated with variations in meat tenderness. Therefore, they could be candidate biomarkers for molecular breeding programs and authentication of the three Spanish beef breedsElsevierUniversidade de Santiago de Compostela. Departamento de Zooloxía, Xenética e Antropoloxía FísicaUniversidade de Santiago de Compostela. Departamento de Bioquímica e Bioloxía MolecularUniversidade de Santiago de Compostela. Departamento de Enxeñaría Química20202020-06-1520202020-06-15journal articlehttp://purl.org/coar/resource_type/c_6501AMhttp://purl.org/coar/version/c_ab4af688f83e57aainfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10347/46146reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostelainstname:Universidad de Santiago de Compostela (USC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:minerva.usc.gal:10347/461462026-06-15T12:47:27Z
dc.title.none.fl_str_mv Measuring quantitative proteomic distance between Spanish beef breeds
title Measuring quantitative proteomic distance between Spanish beef breeds
spellingShingle Measuring quantitative proteomic distance between Spanish beef breeds
Rodríguez Vázquez, Raquel
Meat proteomics
Population proteomics
Proteomic distance measures
QD measure
Beef tenderness biomarkers
Beef authenticity biomarkers
title_short Measuring quantitative proteomic distance between Spanish beef breeds
title_full Measuring quantitative proteomic distance between Spanish beef breeds
title_fullStr Measuring quantitative proteomic distance between Spanish beef breeds
title_full_unstemmed Measuring quantitative proteomic distance between Spanish beef breeds
title_sort Measuring quantitative proteomic distance between Spanish beef breeds
dc.creator.none.fl_str_mv Rodríguez Vázquez, Raquel
Mato Montero, Ariadna
López-Pedrouso, María
Franco Ruiz, Daniel
Sentandreu Vicente, Miguel Ángel
Zapata Babío, José Carlos
author Rodríguez Vázquez, Raquel
author_facet Rodríguez Vázquez, Raquel
Mato Montero, Ariadna
López-Pedrouso, María
Franco Ruiz, Daniel
Sentandreu Vicente, Miguel Ángel
Zapata Babío, José Carlos
author_role author
author2 Mato Montero, Ariadna
López-Pedrouso, María
Franco Ruiz, Daniel
Sentandreu Vicente, Miguel Ángel
Zapata Babío, José Carlos
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de Santiago de Compostela. Departamento de Zooloxía, Xenética e Antropoloxía Física
Universidade de Santiago de Compostela. Departamento de Bioquímica e Bioloxía Molecular
Universidade de Santiago de Compostela. Departamento de Enxeñaría Química
dc.subject.none.fl_str_mv Meat proteomics
Population proteomics
Proteomic distance measures
QD measure
Beef tenderness biomarkers
Beef authenticity biomarkers
topic Meat proteomics
Population proteomics
Proteomic distance measures
QD measure
Beef tenderness biomarkers
Beef authenticity biomarkers
description Estimates of quantitative proteomic distance between populations have not been reported to date. Here, quantitative proteomic distances between three Spanish bovine breeds (Asturiana de los Valles, AV; Retinta, RE; and Rubia Gallega, RG) were estimated from two-dimensional electrophoresis profiles of meat samples of longissimus thoracis muscle at 2 h post-mortem. Statistically significant distances were detected between AV/RG and the most genetically different RE breed, using the novel QD measure of quantitative proteomic distance. In total, 18 differentially abundant myofibrillar and sarcoplasmic proteins/isoforms contributing to proteomic distances between breeds were confidently identified by tandem mass spectrometry. The fast skeletal myosin regulatory light chain 2 followed by other five interacting proteins exhibited the most pronounced relative change between breeds. In addition, most differentially represented proteins could be associated with variations in meat tenderness. Therefore, they could be candidate biomarkers for molecular breeding programs and authentication of the three Spanish beef breeds
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-06-15
2020
2020-06-15
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
AM
http://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/10347/46146
url https://hdl.handle.net/10347/46146
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname:Universidad de Santiago de Compostela (USC)
instname_str Universidad de Santiago de Compostela (USC)
reponame_str Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
collection Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
repository.name.fl_str_mv
repository.mail.fl_str_mv
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