Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R)

Genetic variation at the melanocortin-1 receptor (MC1R) gene is correlated with melanin color variation in many birds. Feral pigeons (Columba livia) show two major melanin-based colorations: a red coloration due to pheomelanic pigment and a black coloration due to eumelanic pigment. Furthermore, wit...

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Autores: Derelle, Romain, Kondrashov, Fyodor A., 1979-, Arkhipov, Vladimir Y., Corbel, Hélène, Frantz, Adrien, Gasparini, Julien, Jacquin, Lisa, Jacob, Gwenaël, Thibault, Sophie, Baudry, Emmanuelle
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:España
Institución:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/21320
Acceso en línea:http://hdl.handle.net/10230/21320
http://dx.doi.org/10.1186/1756-0500-6-310
Access Level:acceso abierto
Palabra clave:Columba livia
Feral pigeon
MC1R
Pigmentation
Color
Birds
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spelling Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R)Derelle, RomainKondrashov, Fyodor A., 1979-Arkhipov, Vladimir Y.Corbel, HélèneFrantz, AdrienGasparini, JulienJacquin, LisaJacob, GwenaëlThibault, SophieBaudry, EmmanuelleColumba liviaFeral pigeonMC1RPigmentationColorBirdsGenetic variation at the melanocortin-1 receptor (MC1R) gene is correlated with melanin color variation in many birds. Feral pigeons (Columba livia) show two major melanin-based colorations: a red coloration due to pheomelanic pigment and a black coloration due to eumelanic pigment. Furthermore, within each color type, feral pigeons display continuous variation in the amount of melanin pigment present in the feathers, with individuals varying from pure white to a full dark melanic color. Coloration is highly heritable and it has been suggested that it is under natural or sexual selection, or both. Our objective was to investigate whether MC1R allelic variants are associated with plumage color in feral pigeons./n/nWe sequenced 888 bp of the coding sequence of MC1R among pigeons varying both in the type, eumelanin or pheomelanin, and the amount of melanin in their feathers. We detected 10 non-synonymous substitutions and 2 synonymous substitution but none of them were associated with a plumage type. It remains possible that non-synonymous substitutions that influence coloration are present in the short MC1R fragment that we did not sequence but this seems unlikely because we analyzed the entire functionally important region of the gene./nOur results show that color differences among feral pigeons are probably not attributable to amino acid variation at the MC1R locus. Therefore, variation in regulatory regions of MC1R or variation in other genes may be responsible for the color polymorphism of feral pigeons.Romain Derelle was supported by grant from Plan Nacional 004302 BFU2012-31329. Fyodor A Kondrashov was supported by grants HHMI (Howard Hughes Medical Institute) 003803 and EMBO 003691 EUI-EURYIP-2011-4320BioMed Central201320132013info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/21320http://dx.doi.org/10.1186/1756-0500-6-310reponame:Repositorio Digital de la UPFinstname:Universitat Pompeu FabraInglésBMC Res. Notes. 2013; 6(1): 310.info:eu-repo/grantAgreement/ES/3PN/BFU2012-31329© Derelle et al. Creative Commons Attribution Licensehttp://creativecommons.org/licenses/by/2.0/info:eu-repo/semantics/openAccessoai:repositori.upf.edu:10230/213202026-06-12T07:21:37Z
dc.title.none.fl_str_mv Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R)
title Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R)
spellingShingle Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R)
Derelle, Romain
Columba livia
Feral pigeon
MC1R
Pigmentation
Color
Birds
title_short Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R)
title_full Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R)
title_fullStr Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R)
title_full_unstemmed Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R)
title_sort Color differences among feral pigeons (Columba livia) are not attributable to sequence variation in the coding region of the melanocortin-1 receptor gene (MC1R)
dc.creator.none.fl_str_mv Derelle, Romain
Kondrashov, Fyodor A., 1979-
Arkhipov, Vladimir Y.
Corbel, Hélène
Frantz, Adrien
Gasparini, Julien
Jacquin, Lisa
Jacob, Gwenaël
Thibault, Sophie
Baudry, Emmanuelle
author Derelle, Romain
author_facet Derelle, Romain
Kondrashov, Fyodor A., 1979-
Arkhipov, Vladimir Y.
Corbel, Hélène
Frantz, Adrien
Gasparini, Julien
Jacquin, Lisa
Jacob, Gwenaël
Thibault, Sophie
Baudry, Emmanuelle
author_role author
author2 Kondrashov, Fyodor A., 1979-
Arkhipov, Vladimir Y.
Corbel, Hélène
Frantz, Adrien
Gasparini, Julien
Jacquin, Lisa
Jacob, Gwenaël
Thibault, Sophie
Baudry, Emmanuelle
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Columba livia
Feral pigeon
MC1R
Pigmentation
Color
Birds
topic Columba livia
Feral pigeon
MC1R
Pigmentation
Color
Birds
description Genetic variation at the melanocortin-1 receptor (MC1R) gene is correlated with melanin color variation in many birds. Feral pigeons (Columba livia) show two major melanin-based colorations: a red coloration due to pheomelanic pigment and a black coloration due to eumelanic pigment. Furthermore, within each color type, feral pigeons display continuous variation in the amount of melanin pigment present in the feathers, with individuals varying from pure white to a full dark melanic color. Coloration is highly heritable and it has been suggested that it is under natural or sexual selection, or both. Our objective was to investigate whether MC1R allelic variants are associated with plumage color in feral pigeons./n/nWe sequenced 888 bp of the coding sequence of MC1R among pigeons varying both in the type, eumelanin or pheomelanin, and the amount of melanin in their feathers. We detected 10 non-synonymous substitutions and 2 synonymous substitution but none of them were associated with a plumage type. It remains possible that non-synonymous substitutions that influence coloration are present in the short MC1R fragment that we did not sequence but this seems unlikely because we analyzed the entire functionally important region of the gene./nOur results show that color differences among feral pigeons are probably not attributable to amino acid variation at the MC1R locus. Therefore, variation in regulatory regions of MC1R or variation in other genes may be responsible for the color polymorphism of feral pigeons.
publishDate 2013
dc.date.none.fl_str_mv 2013
2013
2013
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/21320
http://dx.doi.org/10.1186/1756-0500-6-310
url http://hdl.handle.net/10230/21320
http://dx.doi.org/10.1186/1756-0500-6-310
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv BMC Res. Notes. 2013; 6(1): 310.
info:eu-repo/grantAgreement/ES/3PN/BFU2012-31329
dc.rights.none.fl_str_mv © Derelle et al. Creative Commons Attribution License
http://creativecommons.org/licenses/by/2.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv © Derelle et al. Creative Commons Attribution License
http://creativecommons.org/licenses/by/2.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositorio Digital de la UPF
instname:Universitat Pompeu Fabra
instname_str Universitat Pompeu Fabra
reponame_str Repositorio Digital de la UPF
collection Repositorio Digital de la UPF
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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