Target-site mutations (AChE and kdr), and PSMO activity in codling moth (Cydia pomonella (L.) (Lepidoptera: Tortricidae)) populations from Spain

Codling moth, Cydia pomonella (L.) is a key pest of global importance that affects apple fruit production and whose populations have developed resistance to insecticides in many apple production areas. In Spain, enhanced cytochrome P450 polysubstrate monooxygenase (PSMO) activity is the main mechani...

Descripción completa

Detalles Bibliográficos
Autores: Bosch Serra, Dolors, Avilla Hernández, Jesús, Musleh, Selim, Rodríguez García, Marcela
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2018
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10459.1/62714
Acceso en línea:https://doi.org/10.1016/j.pestbp.2018.02.010
http://hdl.handle.net/10459.1/62714
Access Level:acceso abierto
Palabra clave:Insecticide resistance
AChE and kdr mutations
Frequency of moth with PSMO enhanced activity (R-PSMO)
Spanish apple-growing areas
Resistència als insecticides
Descripción
Sumario:Codling moth, Cydia pomonella (L.) is a key pest of global importance that affects apple fruit production and whose populations have developed resistance to insecticides in many apple production areas. In Spain, enhanced cytochrome P450 polysubstrate monooxygenase (PSMO) activity is the main mechanism involved in insecticide detoxification by codling moth, although acetylcholinesterase (AChE) target site mutations have been described in two populations. However, the extent of AChE and knockdown resistance (kdr) mutations in Spain is unknown. To assess the actual occurrence of AChE and kdr mutations concurrently with the frequency of moths with PSMO enhanced activity (R-PSMO), 32 Spanish field populations from four apple-growing areas of Spain and two susceptible laboratory strains were evaluated. R-PSMO was significantly higher in 23 chemically treated field populations from Extremadura, Catalonia and Aragon, with proportions that varied between 25% and 90%, but no significant differences among strains and the non-chemically treated orchards (organic or abandoned) were observed. The AChE mutation (F290V) was detected in all field populations from Catalonia (n=21) and in three field populations from Aragon (n=5), with resistant phenotype proportions varying from 34.2% to 97.5% and from 7.2% to 65% in Catalonia and Aragon, respectively. In addition, the kdr mutation (L1014F) was detected in twelve Catalonian field populations, at rates of incidence ranging between 2.6% and 56.8%. A positive correlation between R-PSMO and AChE mutation was found. The origin of the mutations and their ability to persist and spread in field populations with different management systems is discussed.