Successful treatment of Pityriasis Versicolor by photodynamic therapy mediated by methylene blue

5 pags., 3 figs.

Detalhes bibliográficos
Autores: Alberdi, E., Gómez-Hernández, María Clara
Formato: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2020
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/221848
Acesso em linha:http://hdl.handle.net/10261/221848
Access Level:acceso abierto
Palavra-chave:Methylene blue
Photodynamic therapy
Pityriasis versicolor
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spelling Successful treatment of Pityriasis Versicolor by photodynamic therapy mediated by methylene blueAlberdi, E.Gómez-Hernández, María ClaraMethylene bluePhotodynamic therapyPityriasis versicolor5 pags., 3 figs.Background: Although systemic therapies are recommended for severe or recalcitrant cases of pityriasis versicolor (PV), they are not free of important side effects and drug interactions. Photodynamic therapy (PDT) utilizes the action of singlet oxygen and free radicals produced by a light-activated photosensitizer to kill viruses, bacteria, or fungi. In this study, the effect of a PDT mediated by methylene blue (MB) in PV was evaluated. Methods: Five women with PV disseminated on the back and diagnosed by fresh microscopic analysis were treated with a solution of MB (2%) applied to the PV lesions for 3 minutes. Next, a red LED lamp (λ = 630±5 nm, 37 J/cm), placed 100 mm from the skin for 10 minutes, was applied on the dyed PV lesions. Six sessions of MB/PDT were implemented with a 2-week interval in between. Wood's lamp examination was used to monitor fungal infection at each time point. Results: Complete cure was observed in the five women at the 4 weeks post-treatment follow-up. Fluoresce images from PV lesions by Wood's lamp allowed to evaluate whether the lesions were healed or not at each time point. No patient showed relapse at the 6-month follow-up. The patients did not have any adverse effect, and good cosmetic outcome was observed. Conclusions: Six sessions of MB/PDT spaced at 14-day intervals are sufficient for the treatment for PV in healthy patients.Spanish Research Projects MINECO. Grant Number: MAT 2017‐83856‐C3 Fundación Eugenio Rodríguez PascualBlackwell PublishingMinisterio de Economía y Competitividad (España)Fundación Eugenio Rodríguez PascualConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]2020202020202020info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Postprintinfo:eu-repo/semantics/acceptedVersionhttp://hdl.handle.net/10261/221848reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/MAT2017‐83856‐C3http://dx.doi.org/10.1111/phpp.12555Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/2218482026-05-22T06:33:51Z
dc.title.none.fl_str_mv Successful treatment of Pityriasis Versicolor by photodynamic therapy mediated by methylene blue
title Successful treatment of Pityriasis Versicolor by photodynamic therapy mediated by methylene blue
spellingShingle Successful treatment of Pityriasis Versicolor by photodynamic therapy mediated by methylene blue
Alberdi, E.
Methylene blue
Photodynamic therapy
Pityriasis versicolor
title_short Successful treatment of Pityriasis Versicolor by photodynamic therapy mediated by methylene blue
title_full Successful treatment of Pityriasis Versicolor by photodynamic therapy mediated by methylene blue
title_fullStr Successful treatment of Pityriasis Versicolor by photodynamic therapy mediated by methylene blue
title_full_unstemmed Successful treatment of Pityriasis Versicolor by photodynamic therapy mediated by methylene blue
title_sort Successful treatment of Pityriasis Versicolor by photodynamic therapy mediated by methylene blue
dc.creator.none.fl_str_mv Alberdi, E.
Gómez-Hernández, María Clara
author Alberdi, E.
author_facet Alberdi, E.
Gómez-Hernández, María Clara
author_role author
author2 Gómez-Hernández, María Clara
author2_role author
dc.contributor.none.fl_str_mv Ministerio de Economía y Competitividad (España)
Fundación Eugenio Rodríguez Pascual
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Methylene blue
Photodynamic therapy
Pityriasis versicolor
topic Methylene blue
Photodynamic therapy
Pityriasis versicolor
description 5 pags., 3 figs.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020
2020
2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Postprint
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/221848
url http://hdl.handle.net/10261/221848
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/MAT2017‐83856‐C3
http://dx.doi.org/10.1111/phpp.12555
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Blackwell Publishing
publisher.none.fl_str_mv Blackwell Publishing
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,81155

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