Pregnant women profile with children with congenital anomalies in Valencian Region

Objective: To describe pregnant women's profile with children with congenital defects (CD) in Valencian Region and to identify differences in pregnancy outcomes based on the characteristics of pregnant. Method: Cross-sectional epidemiological study. Pregnant women with live births or stillbirth...

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Detalles Bibliográficos
Autores: García-Villodre, L, Barrachina-Bonet, L, Páramo-Rodríguez, L, Zurriaga, O, Sorlí, JV, Cavero-Carbonell, C
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Universidad de Málaga
Repositorio:r-FISABIO. Repositorio Institucional de Producción Científica
OAI Identifier:oai:dnet:r-fisabio___::00f310f08a561191e1fe570f3f60d6f8
Acceso en línea:https://fisabio.portalinvestigacion.com/publicaciones/20452
Access Level:acceso abierto
Palabra clave:Congenital defects
Pregnant women
Prevalence
Population register
Public health surveillance
Descripción
Sumario:Objective: To describe pregnant women's profile with children with congenital defects (CD) in Valencian Region and to identify differences in pregnancy outcomes based on the characteristics of pregnant. Method: Cross-sectional epidemiological study. Pregnant women with live births or stillbirths between 2007-2021 were selected from the CD population-based registry of Valencian Region. Pregnant women were classified by: age (< 35 years and >= 35 years), residence province and birth country. The analysis included general descriptive statistics as well as statistics for each characteristic of the pregnant women and the CD of children. To compare the variables, t test or x(2) test were used. CD prevalence (total and by groups) and its 95% confidence intervals per 10,000 births were calculated for the three characteristics. Results: 12,306 pregnant women were identified. 65.0% were < 35 years, 72.9% born in Spain and 45.7% resided in Valencia province. The highest prevalence of CD children with statistically significant differences was in woman pregnant >= 35 years (194.7/10,000 births), not born in Spain (195.9/10,000 births) and residents in Castellon (245.2/10,000 births). Conclusions: The study highlights the relationship between CD and age, residence, and birth country of pregnant women, and confirmed the CD surveillance is a Public Health challenge. (c) 2025 SESPAS. Published by Elsevier Espana, S.L.U. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).