Chondroitin, Dermatan, Heparan, and Keratan Sulfate: Structure and Functions

Sulfated glycosaminoglycans (heparan sulfate, chondroitin sulfate,dermatan sulfate, and keratan sulfate) are a family of complex polysaccharidesubiquitously, but not exclusively, distributed among mammals, found both inextracellular matrices and on cell surfaces. They play key roles in a myriad ofph...

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Detalles Bibliográficos
Autores: Bedini, Emiliano, Corsaro, M. M., Fernández-Mayoralas, Alfonso, Iadonisi, Alfonso
Tipo de recurso: otro
Estado:Versión publicada
Fecha de publicación:2019
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/203447
Acceso en línea:http://hdl.handle.net/10261/203447
Access Level:acceso abierto
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spelling Chondroitin, Dermatan, Heparan, and Keratan Sulfate: Structure and FunctionsBedini, EmilianoCorsaro, M. M.Fernández-Mayoralas, AlfonsoIadonisi, AlfonsoSulfated glycosaminoglycans (heparan sulfate, chondroitin sulfate,dermatan sulfate, and keratan sulfate) are a family of complex polysaccharidesubiquitously, but not exclusively, distributed among mammals, found both inextracellular matrices and on cell surfaces. They play key roles in a myriad ofphysiological and pathological processes, including, among others, angiogenesis,cancer, immunity, and infectious diseases. Here the main issues concerning theirchemical structure, biosynthesis, extraction, and purification from natural sources,structural characterization, as well as their most important biological functions arediscussed.Ministero dell’Istruzione, dell’Università e della Ricerca (MIUR) is acknowl-edged for funding to EB (FFABR 2017,“Fondo per ilfinanziamento delle attività base di ricerca”).AFM thanks the support of the Spanish Ministerio de Economía y Competitividad (GrantMAT2015-65184-C2-2-R)Springer NatureMinisterio de Economía y Competitividad (España)Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]2020202020192020info:eu-repo/semantics/otherhttp://purl.org/coar/resource_type/c_3248Publisher's versioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bookParthttp://hdl.handle.net/10261/203447reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/MAT2015-65184-C2-2-Rhttps://doi.org/10.1007/978-3-030-12919-4_5Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/2034472026-05-22T06:33:51Z
dc.title.none.fl_str_mv Chondroitin, Dermatan, Heparan, and Keratan Sulfate: Structure and Functions
title Chondroitin, Dermatan, Heparan, and Keratan Sulfate: Structure and Functions
spellingShingle Chondroitin, Dermatan, Heparan, and Keratan Sulfate: Structure and Functions
Bedini, Emiliano
title_short Chondroitin, Dermatan, Heparan, and Keratan Sulfate: Structure and Functions
title_full Chondroitin, Dermatan, Heparan, and Keratan Sulfate: Structure and Functions
title_fullStr Chondroitin, Dermatan, Heparan, and Keratan Sulfate: Structure and Functions
title_full_unstemmed Chondroitin, Dermatan, Heparan, and Keratan Sulfate: Structure and Functions
title_sort Chondroitin, Dermatan, Heparan, and Keratan Sulfate: Structure and Functions
dc.creator.none.fl_str_mv Bedini, Emiliano
Corsaro, M. M.
Fernández-Mayoralas, Alfonso
Iadonisi, Alfonso
author Bedini, Emiliano
author_facet Bedini, Emiliano
Corsaro, M. M.
Fernández-Mayoralas, Alfonso
Iadonisi, Alfonso
author_role author
author2 Corsaro, M. M.
Fernández-Mayoralas, Alfonso
Iadonisi, Alfonso
author2_role author
author
author
dc.contributor.none.fl_str_mv Ministerio de Economía y Competitividad (España)
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
description Sulfated glycosaminoglycans (heparan sulfate, chondroitin sulfate,dermatan sulfate, and keratan sulfate) are a family of complex polysaccharidesubiquitously, but not exclusively, distributed among mammals, found both inextracellular matrices and on cell surfaces. They play key roles in a myriad ofphysiological and pathological processes, including, among others, angiogenesis,cancer, immunity, and infectious diseases. Here the main issues concerning theirchemical structure, biosynthesis, extraction, and purification from natural sources,structural characterization, as well as their most important biological functions arediscussed.
publishDate 2019
dc.date.none.fl_str_mv 2019
2020
2020
2020
dc.type.none.fl_str_mv info:eu-repo/semantics/other
http://purl.org/coar/resource_type/c_3248
Publisher's version
info:eu-repo/semantics/publishedVersion
dc.type.openaire.fl_str_mv info:eu-repo/semantics/bookPart
format other
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/203447
url http://hdl.handle.net/10261/203447
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/MAT2015-65184-C2-2-R
https://doi.org/10.1007/978-3-030-12919-4_5
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
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