Trends in the Use and Outcomes of Mechanical Ventilation among Patients Hospitalized with Acute Exacerbations of COPD in Spain, 2001 to 2015

Background: We examine trends (2001–2015) in the use of non-invasive ventilation (NIV) and invasive mechanical ventilation (IMV) among patients hospitalized for acute exacerbation of chronic obstructive pulmonary disease (AE-COPD). Methods: Observational retrospective epidemiological study, using th...

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Autores: Miguel Díez, Javier De, Jiménez García, Rodrigo, Hernández Barrera, V., Puente Maestu, Luis, Girón Matute, Walther Iván, Miguel Yanes, José María De, Méndez Bailón, Manuel, Villanueva Orbaiz, M. Rosa Rita, Albaladejo Vicente, Romana, López De Andrés, Ana Isabel
Tipo de recurso: artículo
Fecha de publicación:2019
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/12577
Acceso en línea:https://hdl.handle.net/20.500.14352/12577
Access Level:acceso abierto
Palabra clave:Chronic obstructive pulmonary disease
Hospitalization
Invasive mechanical ventilation
Non-invasive mechanical ventilation
Trends
Salud pública (Medicina)
3212 Salud Pública
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oai_identifier_str oai:docta.ucm.es:20.500.14352/12577
network_acronym_str ES
network_name_str España
repository_id_str
spelling Trends in the Use and Outcomes of Mechanical Ventilation among Patients Hospitalized with Acute Exacerbations of COPD in Spain, 2001 to 2015Miguel Díez, Javier DeJiménez García, RodrigoHernández Barrera, V.Puente Maestu, LuisGirón Matute, Walther IvánMiguel Yanes, José María DeMéndez Bailón, ManuelVillanueva Orbaiz, M. Rosa RitaAlbaladejo Vicente, RomanaLópez De Andrés, Ana IsabelChronic obstructive pulmonary diseaseHospitalizationInvasive mechanical ventilationNon-invasive mechanical ventilationTrendsSalud pública (Medicina)3212 Salud PúblicaBackground: We examine trends (2001–2015) in the use of non-invasive ventilation (NIV) and invasive mechanical ventilation (IMV) among patients hospitalized for acute exacerbation of chronic obstructive pulmonary disease (AE-COPD). Methods: Observational retrospective epidemiological study, using the Spanish National Hospital Discharge Database. Results: We included 1,431,935 hospitalizations (aged ≥40 years) with an AE-COPD. NIV use increased significantly, from 1.82% in 2001–2003 to 8.52% in 2013–2015, while IMV utilization decreased significantly, from 1.39% in 2001–2003 to 0.67% in 2013–2015. The use of NIV + invasive mechanical ventilation (IMV) rose significantly over time (from 0.17% to 0.42%). Despite the worsening of clinical profile of patients, length of stay decreased significantly over time in all types of ventilation. Patients who received only IMV had the highest in-hospital mortality (IHM) (32.63%). IHM decreased significantly in patients with NIV + IMV, but it remained stable in those receiving isolated NIV and isolated IMV. Factors associated with use of any type of ventilatory support included female sex, lower age, and higher comorbidity. Conclusions: We found an increase in NIV use and a decline in IMV utilization to treat AE-COPD among hospitalized patients. The IHM decreased significantly over time in patients who received NIV + IMV, but it remained stable in patients who received NIV or IMV in isolation.MDPIUniversidad Complutense de Madrid20192019-10-0420192019-10-04journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14352/12577reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Atribución 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/125772026-06-02T12:44:21Z
dc.title.none.fl_str_mv Trends in the Use and Outcomes of Mechanical Ventilation among Patients Hospitalized with Acute Exacerbations of COPD in Spain, 2001 to 2015
title Trends in the Use and Outcomes of Mechanical Ventilation among Patients Hospitalized with Acute Exacerbations of COPD in Spain, 2001 to 2015
spellingShingle Trends in the Use and Outcomes of Mechanical Ventilation among Patients Hospitalized with Acute Exacerbations of COPD in Spain, 2001 to 2015
Miguel Díez, Javier De
Chronic obstructive pulmonary disease
Hospitalization
Invasive mechanical ventilation
Non-invasive mechanical ventilation
Trends
Salud pública (Medicina)
3212 Salud Pública
title_short Trends in the Use and Outcomes of Mechanical Ventilation among Patients Hospitalized with Acute Exacerbations of COPD in Spain, 2001 to 2015
title_full Trends in the Use and Outcomes of Mechanical Ventilation among Patients Hospitalized with Acute Exacerbations of COPD in Spain, 2001 to 2015
title_fullStr Trends in the Use and Outcomes of Mechanical Ventilation among Patients Hospitalized with Acute Exacerbations of COPD in Spain, 2001 to 2015
title_full_unstemmed Trends in the Use and Outcomes of Mechanical Ventilation among Patients Hospitalized with Acute Exacerbations of COPD in Spain, 2001 to 2015
title_sort Trends in the Use and Outcomes of Mechanical Ventilation among Patients Hospitalized with Acute Exacerbations of COPD in Spain, 2001 to 2015
dc.creator.none.fl_str_mv Miguel Díez, Javier De
Jiménez García, Rodrigo
Hernández Barrera, V.
Puente Maestu, Luis
Girón Matute, Walther Iván
Miguel Yanes, José María De
Méndez Bailón, Manuel
Villanueva Orbaiz, M. Rosa Rita
Albaladejo Vicente, Romana
López De Andrés, Ana Isabel
author Miguel Díez, Javier De
author_facet Miguel Díez, Javier De
Jiménez García, Rodrigo
Hernández Barrera, V.
Puente Maestu, Luis
Girón Matute, Walther Iván
Miguel Yanes, José María De
Méndez Bailón, Manuel
Villanueva Orbaiz, M. Rosa Rita
Albaladejo Vicente, Romana
López De Andrés, Ana Isabel
author_role author
author2 Jiménez García, Rodrigo
Hernández Barrera, V.
Puente Maestu, Luis
Girón Matute, Walther Iván
Miguel Yanes, José María De
Méndez Bailón, Manuel
Villanueva Orbaiz, M. Rosa Rita
Albaladejo Vicente, Romana
López De Andrés, Ana Isabel
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidad Complutense de Madrid
dc.subject.none.fl_str_mv Chronic obstructive pulmonary disease
Hospitalization
Invasive mechanical ventilation
Non-invasive mechanical ventilation
Trends
Salud pública (Medicina)
3212 Salud Pública
topic Chronic obstructive pulmonary disease
Hospitalization
Invasive mechanical ventilation
Non-invasive mechanical ventilation
Trends
Salud pública (Medicina)
3212 Salud Pública
description Background: We examine trends (2001–2015) in the use of non-invasive ventilation (NIV) and invasive mechanical ventilation (IMV) among patients hospitalized for acute exacerbation of chronic obstructive pulmonary disease (AE-COPD). Methods: Observational retrospective epidemiological study, using the Spanish National Hospital Discharge Database. Results: We included 1,431,935 hospitalizations (aged ≥40 years) with an AE-COPD. NIV use increased significantly, from 1.82% in 2001–2003 to 8.52% in 2013–2015, while IMV utilization decreased significantly, from 1.39% in 2001–2003 to 0.67% in 2013–2015. The use of NIV + invasive mechanical ventilation (IMV) rose significantly over time (from 0.17% to 0.42%). Despite the worsening of clinical profile of patients, length of stay decreased significantly over time in all types of ventilation. Patients who received only IMV had the highest in-hospital mortality (IHM) (32.63%). IHM decreased significantly in patients with NIV + IMV, but it remained stable in those receiving isolated NIV and isolated IMV. Factors associated with use of any type of ventilatory support included female sex, lower age, and higher comorbidity. Conclusions: We found an increase in NIV use and a decline in IMV utilization to treat AE-COPD among hospitalized patients. The IHM decreased significantly over time in patients who received NIV + IMV, but it remained stable in patients who received NIV or IMV in isolation.
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-10-04
2019
2019-10-04
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/12577
url https://hdl.handle.net/20.500.14352/12577
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 3.0 España
https://creativecommons.org/licenses/by/3.0/es/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 3.0 España
https://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,301629

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