SEOM clinical guidelines for the diagnosis and treatment of gastroenteropancreatic and bronchial neuroendocrine neoplasms (NENs) (2018)

NENs are a heterogeneous family of tumors of challenging diagnosis and clinical management. Their incidence and prevalence continue to rise across all sites, stages and grades. Although improved diagnostic techniques have led to earlier detection and stage migration, the improved prognosis documente...

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Detalhes bibliográficos
Autores: González-Flores, Encarnación, Serrano, R., Sevilla, I., Viudez, Antonio, Barriuso, Jorge, Benavent, Marta, Capdevila, Jaume, Jiménez-Fonseca, Paula, López, Carlos, García-Carbonero, Rocío
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/198840
Acesso em linha:http://hdl.handle.net/10261/198840
Access Level:acceso abierto
Palavra-chave:Guidelines
Neuroendocrine tumors
Neuroendocrine neoplasms
Gastroenteropancreatic
Lung
Diagnosis
Therapy
Descrição
Resumo:NENs are a heterogeneous family of tumors of challenging diagnosis and clinical management. Their incidence and prevalence continue to rise across all sites, stages and grades. Although improved diagnostic techniques have led to earlier detection and stage migration, the improved prognosis documented over time for advanced gastrointestinal and pancreatic neuroendocrine tumors also reflect improvements in therapy. The aim of this guideline is to update practical recommendations for the diagnosis and treatment of gastroenteropancreatic and lung NENs. Diagnostic procedures, histological classification and therapeutic options are briefly discussed, including surgery, liver-directed therapy, peptide receptor radionuclide therapy, and systemic hormonal, cytotoxic or targeted therapy, and treatment algorithms are provided.