The Use of Antibiotics for Uncomplicated Urinary Tract Infections in Adult Women: Qualitative Findings From the SCOUT Trial

BACKGROUND: This paper focuses on women's subjective experiences with UTIs and antibiotic use. Uncomplicated urinary tract infections (UTI) are among the most common infections treated in primary care, however, there is limited evidence regarding the experiences and their antibiotic treatment p...

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Autores: Munné-Barellas, Berta, Monfà, Ramon, Llor, Carl, Garcia-Sangenís, Ana, Miranda-Jiménez, Cristina, Morros, Rosa, Moragas, Ana, Alvarez-Greciano, Pablo, Leiva, Alfonso, Lozano-Del Hoyo, Mª Luisa, Sánchez-Calavera, Maria Antonia, Marín-Cañada, Jaime, Sánchez-Ruano, Raquel
Tipo de recurso: artículo
Fecha de publicación:2025
País:España
Institución:Conselleria de Salut i Consum del Govern de les Illes Balears
Repositorio:Docusalut
Idioma:inglés
OAI Identifier:oai:docusalut.com:20.500.13003/25889
Acceso en línea:https://hdl.handle.net/20.500.13003/25889
Access Level:acceso abierto
Palabra clave:Antibiotic Prophylaxis
Clinical Trial
Patient Satisfaction
Qualitative Research
Urinary Tract Infections
Women
Profilaxis Antibiótica
Ensayo Clínico
Satisfacción del Paciente
Investigación Cualitativa
Infecciones Urinarias
Mujeres
antibiotic
clinical trial
patient satisfaction
qualitative research
urinary tract infection
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spelling The Use of Antibiotics for Uncomplicated Urinary Tract Infections in Adult Women: Qualitative Findings From the SCOUT TrialMunné-Barellas, BertaMonfà, RamonLlor, CarlGarcia-Sangenís, AnaMiranda-Jiménez, CristinaMorros, RosaMoragas, AnaAlvarez-Greciano, PabloLeiva, AlfonsoLozano-Del Hoyo, Mª LuisaSánchez-Calavera, Maria AntoniaMarín-Cañada, JaimeSánchez-Ruano, RaquelAntibiotic ProphylaxisClinical TrialPatient SatisfactionQualitative ResearchUrinary Tract InfectionsWomenProfilaxis AntibióticaEnsayo ClínicoSatisfacción del PacienteInvestigación CualitativaInfecciones UrinariasMujeresantibioticclinical trialpatient satisfactionqualitative researchurinary tract infectionWomenBACKGROUND: This paper focuses on women's subjective experiences with UTIs and antibiotic use. Uncomplicated urinary tract infections (UTI) are among the most common infections treated in primary care, however, there is limited evidence regarding the experiences and their antibiotic treatment preferences. OBJECTIVE: The aim of this study is to gather experiences, beliefs, and attitudes regarding the use of antibiotics and the participation in the clinical trial. METHODS: This qualitative sub-study is part of the SCOUT project, which, through a clinical trial, aims to assess the effectiveness of four short antibiotic regimens (a single 3g dose of fosfomycin; 3g of fosfomycin for two days; 400mg of pivmecillinam for three days; and 100mg of nitrofurantoin for five days). A total of 68 semi-structured interviews were conducted in four regions of Spain (Catalonia N=19, Aragón N=19, Madrid N=15, and the Balearic Islands N=15). A purposive and theoretical sampling approach was employed. Participants were recruited after taking part in the clinical trial. Data collection took place between March and July 2024 and analysed using Thematic Analysis. RESULTS: UTI did not cause excessive concern, except in cases where the antibiotic was ineffective or when participants had experienced multiple infections in the past. Fosfomycin was the most widely recognized antibiotic, and the two-dose regimen was generally well-regarded for being easy to take while also being more effective than the single-dose treatment. Longer regimens could cause some side effects, but in certain cases, they were perceived as more effective. Participation in the clinical trial was viewed positively, as it contributed to increasing overall knowledge about UTI and the antibiotics used to treat them, as well as ensuring closer monitoring of each specific case. CONCLUSION: This study gathers experiences related to UTI, antibiotic treatment regimens, and participation in the SCOUT clinical trial. It highlights the need to document the realities of UTI in order to improve future clinical trials.Dove20252025-01-0120252025-01-01research articlehttp://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.13003/25889reponame:Docusalutinstname:Conselleria de Salut i Consum del Govern de les Illes BalearsInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessoai:docusalut.com:20.500.13003/258892026-06-22T12:44:07Z
dc.title.none.fl_str_mv The Use of Antibiotics for Uncomplicated Urinary Tract Infections in Adult Women: Qualitative Findings From the SCOUT Trial
title The Use of Antibiotics for Uncomplicated Urinary Tract Infections in Adult Women: Qualitative Findings From the SCOUT Trial
spellingShingle The Use of Antibiotics for Uncomplicated Urinary Tract Infections in Adult Women: Qualitative Findings From the SCOUT Trial
Munné-Barellas, Berta
Antibiotic Prophylaxis
Clinical Trial
Patient Satisfaction
Qualitative Research
Urinary Tract Infections
Women
Profilaxis Antibiótica
Ensayo Clínico
Satisfacción del Paciente
Investigación Cualitativa
Infecciones Urinarias
Mujeres
antibiotic
clinical trial
patient satisfaction
qualitative research
urinary tract infection
Women
title_short The Use of Antibiotics for Uncomplicated Urinary Tract Infections in Adult Women: Qualitative Findings From the SCOUT Trial
title_full The Use of Antibiotics for Uncomplicated Urinary Tract Infections in Adult Women: Qualitative Findings From the SCOUT Trial
title_fullStr The Use of Antibiotics for Uncomplicated Urinary Tract Infections in Adult Women: Qualitative Findings From the SCOUT Trial
title_full_unstemmed The Use of Antibiotics for Uncomplicated Urinary Tract Infections in Adult Women: Qualitative Findings From the SCOUT Trial
title_sort The Use of Antibiotics for Uncomplicated Urinary Tract Infections in Adult Women: Qualitative Findings From the SCOUT Trial
dc.creator.none.fl_str_mv Munné-Barellas, Berta
Monfà, Ramon
Llor, Carl
Garcia-Sangenís, Ana
Miranda-Jiménez, Cristina
Morros, Rosa
Moragas, Ana
Alvarez-Greciano, Pablo
Leiva, Alfonso
Lozano-Del Hoyo, Mª Luisa
Sánchez-Calavera, Maria Antonia
Marín-Cañada, Jaime
Sánchez-Ruano, Raquel
author Munné-Barellas, Berta
author_facet Munné-Barellas, Berta
Monfà, Ramon
Llor, Carl
Garcia-Sangenís, Ana
Miranda-Jiménez, Cristina
Morros, Rosa
Moragas, Ana
Alvarez-Greciano, Pablo
Leiva, Alfonso
Lozano-Del Hoyo, Mª Luisa
Sánchez-Calavera, Maria Antonia
Marín-Cañada, Jaime
Sánchez-Ruano, Raquel
author_role author
author2 Monfà, Ramon
Llor, Carl
Garcia-Sangenís, Ana
Miranda-Jiménez, Cristina
Morros, Rosa
Moragas, Ana
Alvarez-Greciano, Pablo
Leiva, Alfonso
Lozano-Del Hoyo, Mª Luisa
Sánchez-Calavera, Maria Antonia
Marín-Cañada, Jaime
Sánchez-Ruano, Raquel
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Antibiotic Prophylaxis
Clinical Trial
Patient Satisfaction
Qualitative Research
Urinary Tract Infections
Women
Profilaxis Antibiótica
Ensayo Clínico
Satisfacción del Paciente
Investigación Cualitativa
Infecciones Urinarias
Mujeres
antibiotic
clinical trial
patient satisfaction
qualitative research
urinary tract infection
Women
topic Antibiotic Prophylaxis
Clinical Trial
Patient Satisfaction
Qualitative Research
Urinary Tract Infections
Women
Profilaxis Antibiótica
Ensayo Clínico
Satisfacción del Paciente
Investigación Cualitativa
Infecciones Urinarias
Mujeres
antibiotic
clinical trial
patient satisfaction
qualitative research
urinary tract infection
Women
description BACKGROUND: This paper focuses on women's subjective experiences with UTIs and antibiotic use. Uncomplicated urinary tract infections (UTI) are among the most common infections treated in primary care, however, there is limited evidence regarding the experiences and their antibiotic treatment preferences. OBJECTIVE: The aim of this study is to gather experiences, beliefs, and attitudes regarding the use of antibiotics and the participation in the clinical trial. METHODS: This qualitative sub-study is part of the SCOUT project, which, through a clinical trial, aims to assess the effectiveness of four short antibiotic regimens (a single 3g dose of fosfomycin; 3g of fosfomycin for two days; 400mg of pivmecillinam for three days; and 100mg of nitrofurantoin for five days). A total of 68 semi-structured interviews were conducted in four regions of Spain (Catalonia N=19, Aragón N=19, Madrid N=15, and the Balearic Islands N=15). A purposive and theoretical sampling approach was employed. Participants were recruited after taking part in the clinical trial. Data collection took place between March and July 2024 and analysed using Thematic Analysis. RESULTS: UTI did not cause excessive concern, except in cases where the antibiotic was ineffective or when participants had experienced multiple infections in the past. Fosfomycin was the most widely recognized antibiotic, and the two-dose regimen was generally well-regarded for being easy to take while also being more effective than the single-dose treatment. Longer regimens could cause some side effects, but in certain cases, they were perceived as more effective. Participation in the clinical trial was viewed positively, as it contributed to increasing overall knowledge about UTI and the antibiotics used to treat them, as well as ensuring closer monitoring of each specific case. CONCLUSION: This study gathers experiences related to UTI, antibiotic treatment regimens, and participation in the SCOUT clinical trial. It highlights the need to document the realities of UTI in order to improve future clinical trials.
publishDate 2025
dc.date.none.fl_str_mv 2025
2025-01-01
2025
2025-01-01
dc.type.none.fl_str_mv research article
http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.13003/25889
url https://hdl.handle.net/20.500.13003/25889
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Dove
publisher.none.fl_str_mv Dove
dc.source.none.fl_str_mv reponame:Docusalut
instname:Conselleria de Salut i Consum del Govern de les Illes Balears
instname_str Conselleria de Salut i Consum del Govern de les Illes Balears
reponame_str Docusalut
collection Docusalut
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repository.mail.fl_str_mv
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