Consumption of watermelon juice enriched in L-citrulline and pomegranate ellagitannins enhanced metabolism during physical exercise

L-Citrulline is a nonessential amino acid precursor of arginine and indirectly a precursor of nitric oxide (NO), which is a vasodilator and increases mitochondrial respiration. On the other hand, the antioxidant pomegranate ellagitannins are precursors of urolithin A, which has been associated with...

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Detalhes bibliográficos
Autores: Martínez Sánchez, Ascensión, Alacid, Fernando, Rubio Arias, Jacobo Ángel, Fernández Lobato, Bárbara, Ramos Campo, Domingo Jesús, Aguayo, Encarna
Formato: artículo
Fecha de publicación:2017
País:España
Recursos:Universidad Católica San Antonio de Murcia (UCAM)
Repositorio:RIUCAM. Repositorio Institucional de la Universidad Católica San Antonio de Murcia
OAI Identifier:oai:repositorio.ucam.edu:10952/3068
Acesso em linha:http://hdl.handle.net/10952/3068
Access Level:acceso abierto
Palavra-chave:Arginine
Creatinine
Ellagitannins
Ergogenic aid
I-citrulline
Lactate dehydrogenase
Myoglobin
Pomegranate
Urea
Watermelon
Descrição
Resumo:L-Citrulline is a nonessential amino acid precursor of arginine and indirectly a precursor of nitric oxide (NO), which is a vasodilator and increases mitochondrial respiration. On the other hand, the antioxidant pomegranate ellagitannins are precursors of urolithin A, which has been associated with mitophagy and increased muscle function. To elucidate if a single dose of watermelon enrichment with these compounds could have a positive effect after high-intensity exercise (eight sets of eight repetitions of half-squat exercise), a double-blind randomized crossover in vivo study was performed in healthy male subjects (n = 19). Enrichment juices maintained basal levels of blood markers of muscle damage, such as lactate dehydrogenase and myoglobin, and showed a significant maintenance of force during the exercise and a significant decrease in the rating of perceived exertion and muscle soreness after exercise. A positive effect was observed between l-citrulline and ellagitannins, improving the ergogenic effect of watermelon juice.