Comparing the Proteomic Profiles of Extracellular Vesicles Isolated using Different Methods from Long-term Stored Plasma Samples

The lack of standardized protocols for isolating extracellular vesicles (EVs), especially from biobank-stored blood plasma, translates to limitations for the study of new biomarkers. This study examines whether a combination of current isolation methods could enhance the specificity and purity of is...

ver descrição completa

Detalhes bibliográficos
Autores: Torres, Ana, Bernardo, Lorena, Sánchez, Carmen, Morato, Esperanza, Solana, José Carlos, Carrillo, Eugenia
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/366548
Acesso em linha:http://hdl.handle.net/10261/366548
Access Level:acceso abierto
Palavra-chave:Extracellular Vesicles
Plasma
Proteomics
Size Exclusion Chromatography
Ultracentrifugation.
Descrição
Resumo:The lack of standardized protocols for isolating extracellular vesicles (EVs), especially from biobank-stored blood plasma, translates to limitations for the study of new biomarkers. This study examines whether a combination of current isolation methods could enhance the specificity and purity of isolated EVs for diagnosis and personalized medicine purposes.

Registos relacionados