Clinical and Pathological Findings Associated with Mycobacteriosis in Captive Syngnathids

[EN] Mycobacteriosis is an important disease that affects captive and wild aquatic fish. Syngnathids are susceptible to infection by non-tuberculous mycobacteria. The aim of this study was to describe clinical signs, and macroscopic and histological lesions in 25 syngnathids and the molecular charac...

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Detalles Bibliográficos
Autores: Montero, Estefanía, Rojo Solís, Carlos, Castro, Noelia de, Fernández Fernández, Miguel, Pérez Pérez, Valentín, Corpa, Juan M., Ortega, Joaquín
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Ajuntament de Barcelona
Repositorio:BULERIA. Repositorio Institucional de la Universidad de León
OAI Identifier:oai:buleria.unileon.es:10612/18724
Acceso en línea:https://www.mdpi.com/2076-2615/12/23/3259
https://hdl.handle.net/10612/18724
Access Level:acceso abierto
Palabra clave:Sanidad animal
Granuloma
Mycobacteriosis
Mycobacterium chelonae
Mycobacterium fortuitum
Mycobacterium marinum
Pathology
Pipefish
Sea dragon
Seahorse
Syngnathids
3109 Ciencias Veterinarias
Descripción
Sumario:[EN] Mycobacteriosis is an important disease that affects captive and wild aquatic fish. Syngnathids are susceptible to infection by non-tuberculous mycobacteria. The aim of this study was to describe clinical signs, and macroscopic and histological lesions in 25 syngnathids and the molecular characterization of the causative mycobacteria. Clinical presentation ranged from sudden death to non-specific signs, including anorexia, poor body condition, weight loss and marked dyspnea with increased respiratory effort and rate. Gross lesions were mostly ulcers on the tail and small white nodules in the liver, coelomic cavity and inside the eye. The most affected organs were gills, liver, intestine and coelomic mesentery. Microscopic lesions consisted of areas of multifocal to diffuse granulomatous inflammation and bacterial emboli with numerous intralesional acid-fast bacilli. Epithelioid cells, multinucleated giant cells, lymphocytes and fibrous connective tissue, which are commonly observed in granulomatous inflammation, were not observed here. In the real-time PCR, M. fortuitum, M. chelonae and M. marinum common primers, Mycobacterium spp. were detected in 4, 7 and 14 individuals, respectively. In addition, this is the first description of mycobacteriosis found in Syngnathus acus