REPlicating RAPid microfluidics: self-replicating printer for hydrophobic pattern deposition

Paper-based microfluidics broadens the use of point-of-care devices to applications and situations wherein cost is an important restriction. This study focuses on the REPRAP PRUSA i3 Printer that can print itself a part that combined with an infusion pump extends the capabilities of this printer, wh...

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Detalles Bibliográficos
Autores: Casals Terré, Jasmina|||0000-0002-1368-3950, Farré Lladós, Josep|||0000-0001-5909-0176, Zuñiga, Allinson, Roncero Vivero, María Blanca|||0000-0002-2694-2368, Vidal Lluciá, Teresa|||0000-0001-6269-4114
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/115885
Acceso en línea:https://hdl.handle.net/2117/115885
https://dx.doi.org/10.1089/3dp.2017.0042
Access Level:acceso abierto
Palabra clave:Microfluidic devices
Three-dimensional printing
Lab on a chip
3D printer
Paper-based microfluidics
Blood type assay
Point-of-care testing
Dispositius microfluidics
Impressió 3D
Àrees temàtiques de la UPC::Enginyeria dels materials
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spelling REPlicating RAPid microfluidics: self-replicating printer for hydrophobic pattern depositionCasals Terré, Jasmina|||0000-0002-1368-3950Farré Lladós, Josep|||0000-0001-5909-0176Zuñiga, AllinsonRoncero Vivero, María Blanca|||0000-0002-2694-2368Vidal Lluciá, Teresa|||0000-0001-6269-4114Microfluidic devicesThree-dimensional printingLab on a chip3D printerPaper-based microfluidicsBlood type assayPoint-of-care testingDispositius microfluidicsImpressió 3DÀrees temàtiques de la UPC::Enginyeria dels materialsPaper-based microfluidics broadens the use of point-of-care devices to applications and situations wherein cost is an important restriction. This study focuses on the REPRAP PRUSA i3 Printer that can print itself a part that combined with an infusion pump extends the capabilities of this printer, which can now create different types of hydrophobic patterns on an abundant, renewable substrate: paper. Different flow rates of the syringe pump and printing velocities are combined to optimize the resolution of this new manufacturing process. Besides different papers are used to print patterns to either check the influence of the paper type on the printing resolution or to choose the more suitable paper to build blood typing assays. The resolution improves decreasing flow rate and increasing printing velocity to a minimum value ~10% higher than the needle diameter. The printer working with a G25 needle prints microfluidic patterns that can be used to evaluate the blood type on different types of chromatographic papers. Two blood types (A- and O-) are evaluated with this new approach with results equivalent to traditional methods, validating its feasibility in clinical practice. This novel printing method for paper-based microfluidics manufacturing does not require specialized equipment or skills, it is fast and inexpensive, and thus can help to introduce the advantage of healthcare in areas where access to health systems is not guaranteed.Peer Reviewed20172017-12-0120182018-04-03journal articlehttp://purl.org/coar/resource_type/c_6501AMhttp://purl.org/coar/version/c_ab4af688f83e57aainfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/2117/115885https://dx.doi.org/10.1089/3dp.2017.0042reponame:UPCommons. Portal del coneixement obert de la UPCinstname:Universitat Politècnica de Catalunya (UPC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:upcommons.upc.edu:2117/1158852026-05-27T15:37:01Z
dc.title.none.fl_str_mv REPlicating RAPid microfluidics: self-replicating printer for hydrophobic pattern deposition
title REPlicating RAPid microfluidics: self-replicating printer for hydrophobic pattern deposition
spellingShingle REPlicating RAPid microfluidics: self-replicating printer for hydrophobic pattern deposition
Casals Terré, Jasmina|||0000-0002-1368-3950
Microfluidic devices
Three-dimensional printing
Lab on a chip
3D printer
Paper-based microfluidics
Blood type assay
Point-of-care testing
Dispositius microfluidics
Impressió 3D
Àrees temàtiques de la UPC::Enginyeria dels materials
title_short REPlicating RAPid microfluidics: self-replicating printer for hydrophobic pattern deposition
title_full REPlicating RAPid microfluidics: self-replicating printer for hydrophobic pattern deposition
title_fullStr REPlicating RAPid microfluidics: self-replicating printer for hydrophobic pattern deposition
title_full_unstemmed REPlicating RAPid microfluidics: self-replicating printer for hydrophobic pattern deposition
title_sort REPlicating RAPid microfluidics: self-replicating printer for hydrophobic pattern deposition
dc.creator.none.fl_str_mv Casals Terré, Jasmina|||0000-0002-1368-3950
Farré Lladós, Josep|||0000-0001-5909-0176
Zuñiga, Allinson
Roncero Vivero, María Blanca|||0000-0002-2694-2368
Vidal Lluciá, Teresa|||0000-0001-6269-4114
author Casals Terré, Jasmina|||0000-0002-1368-3950
author_facet Casals Terré, Jasmina|||0000-0002-1368-3950
Farré Lladós, Josep|||0000-0001-5909-0176
Zuñiga, Allinson
Roncero Vivero, María Blanca|||0000-0002-2694-2368
Vidal Lluciá, Teresa|||0000-0001-6269-4114
author_role author
author2 Farré Lladós, Josep|||0000-0001-5909-0176
Zuñiga, Allinson
Roncero Vivero, María Blanca|||0000-0002-2694-2368
Vidal Lluciá, Teresa|||0000-0001-6269-4114
author2_role author
author
author
author
dc.subject.none.fl_str_mv Microfluidic devices
Three-dimensional printing
Lab on a chip
3D printer
Paper-based microfluidics
Blood type assay
Point-of-care testing
Dispositius microfluidics
Impressió 3D
Àrees temàtiques de la UPC::Enginyeria dels materials
topic Microfluidic devices
Three-dimensional printing
Lab on a chip
3D printer
Paper-based microfluidics
Blood type assay
Point-of-care testing
Dispositius microfluidics
Impressió 3D
Àrees temàtiques de la UPC::Enginyeria dels materials
description Paper-based microfluidics broadens the use of point-of-care devices to applications and situations wherein cost is an important restriction. This study focuses on the REPRAP PRUSA i3 Printer that can print itself a part that combined with an infusion pump extends the capabilities of this printer, which can now create different types of hydrophobic patterns on an abundant, renewable substrate: paper. Different flow rates of the syringe pump and printing velocities are combined to optimize the resolution of this new manufacturing process. Besides different papers are used to print patterns to either check the influence of the paper type on the printing resolution or to choose the more suitable paper to build blood typing assays. The resolution improves decreasing flow rate and increasing printing velocity to a minimum value ~10% higher than the needle diameter. The printer working with a G25 needle prints microfluidic patterns that can be used to evaluate the blood type on different types of chromatographic papers. Two blood types (A- and O-) are evaluated with this new approach with results equivalent to traditional methods, validating its feasibility in clinical practice. This novel printing method for paper-based microfluidics manufacturing does not require specialized equipment or skills, it is fast and inexpensive, and thus can help to introduce the advantage of healthcare in areas where access to health systems is not guaranteed.
publishDate 2017
dc.date.none.fl_str_mv 2017
2017-12-01
2018
2018-04-03
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
AM
http://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/2117/115885
https://dx.doi.org/10.1089/3dp.2017.0042
url https://hdl.handle.net/2117/115885
https://dx.doi.org/10.1089/3dp.2017.0042
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:UPCommons. Portal del coneixement obert de la UPC
instname:Universitat Politècnica de Catalunya (UPC)
instname_str Universitat Politècnica de Catalunya (UPC)
reponame_str UPCommons. Portal del coneixement obert de la UPC
collection UPCommons. Portal del coneixement obert de la UPC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300724

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