Complementary regioselectivity in the synthesis of iminohydantoins: remarkable effect of amide substitution on the cyclization

Complementary regioselective synthesis of iminohydantoins from isocyanoacetamides controlled by the substituent on the amide group has been described. 4-Iminohydantoins were the major products when the starting materials were N-alkyl isocyanoamides, whereas 2-iminohydantoins were the major products...

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Detalles Bibliográficos
Autores: García Valverde, María, Marcaccini, Stefano ., González Ortega, Alfonso ., Rodríguez Vidal, Francisco Javier, Rojo Cámara, Mª Josefa, Torroba Pérez, Tomás
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2013
País:España
Institución:Universidad de Burgos (UBU)
Repositorio:Repositorio Institucional de la Universidad de Burgos (RIUBU)
OAI Identifier:oai:riubu.ubu.es:10259/4878
Acceso en línea:http://hdl.handle.net/10259/4878
Access Level:acceso abierto
Palabra clave:Química orgánica
Chemistry, Organic
Descripción
Sumario:Complementary regioselective synthesis of iminohydantoins from isocyanoacetamides controlled by the substituent on the amide group has been described. 4-Iminohydantoins were the major products when the starting materials were N-alkyl isocyanoamides, whereas 2-iminohydantoins were the major products with N-aryl isocyanoamides.