MitoBlue as a tool to analyze the mitochondria-lysosome communication

MitoBlue is a fluorescent bisamidine that can be used to easily monitor the changes in mitochondrial degradation processes in different cells and cellular conditions. MitoBlue staining pattern is exceptional among mitochondrial dyes and recombinant fluorescent probes, allowing the dynamic study of m...

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Detalles Bibliográficos
Autores: Sánchez, Mateo I., Vida, Yolanda, Pérez-Inestrosa, Ezequiel, Mascareñas, José L., Vázquez, M. Eugenio, Sugiura, Ayumu, Martínez-Costas, José
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/18006
Acceso en línea:http://hdl.handle.net/20.500.12105/18006
Access Level:acceso abierto
Palabra clave:Mitochondrial degradation
Lysosome
Microscopy
Mitochondria
Proteins
Quality control
Mitofagia
Lisosomas
Microscopía
Mitocondrias
Proteínas
Control de calidad
2-Naphthylamine
Amidines
Animals
Chick Embryo
Fibroblasts
Lysosomes
Microscopy, Fluorescence
Fluorescent Dyes
Descripción
Sumario:MitoBlue is a fluorescent bisamidine that can be used to easily monitor the changes in mitochondrial degradation processes in different cells and cellular conditions. MitoBlue staining pattern is exceptional among mitochondrial dyes and recombinant fluorescent probes, allowing the dynamic study of mitochondrial recycling in a variety of situations in living cells. MitoBlue is a unique tool for the study of these processes that will allow the detailed characterization of communication between mitochondria and lysosomes.