Mechanisms of change in long-term transdiagnostic cognitive behavioural therapy: the sequential effect of rumination and worry on symptoms and quality of life

Anxiety and depressive disorders are the most prevalent disorders worldwide and significantly impair quality of life (QoL). Transdiagnostic cognitive behavioural therapy (TD-CBT) is effective in treating these disorders and improving QoL, but its long-term mechanisms of change are poorly understood....

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Autores: Esteller Collado, Gabriel, Prieto Vila, Maider, Carpallo González, María, Antuña Camblor, Celia, Ruiz Rodríguez, Paloma, González Blanch, César, Moriana, Juan Antonio, Cano Vindel, Antonio, Muñoz Navarro, Roger
Tipo de recurso: artículo
Fecha de publicación:2025
País:España
Institución:Universidad Europea (UEM)
Repositorio:ABACUS. Repositorio de Producción Científica
Idioma:inglés
OAI Identifier:oai:abacus.universidadeuropea.com:11268/16474
Acceso en línea:https://hdl.handle.net/11268/16474
Access Level:acceso abierto
Palabra clave:Ciencias médicas
Psicología clínica
Psicología social
Goal 3: Ensure healthy lives and promote well-being for all at all ages
Goal 4: Quality education
Goal 5: Achieve gender equality and empower all women and girls
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spelling Mechanisms of change in long-term transdiagnostic cognitive behavioural therapy: the sequential effect of rumination and worry on symptoms and quality of lifeEsteller Collado, GabrielPrieto Vila, MaiderCarpallo González, MaríaAntuña Camblor, CeliaRuiz Rodríguez, PalomaGonzález Blanch, CésarMoriana, Juan AntonioCano Vindel, AntonioMuñoz Navarro, RogerCiencias médicasPsicología clínicaPsicología socialGoal 3: Ensure healthy lives and promote well-being for all at all agesGoal 4: Quality educationGoal 5: Achieve gender equality and empower all women and girlsAnxiety and depressive disorders are the most prevalent disorders worldwide and significantly impair quality of life (QoL). Transdiagnostic cognitive behavioural therapy (TD-CBT) is effective in treating these disorders and improving QoL, but its long-term mechanisms of change are poorly understood. Rumination and worry are key processes addressed by TD-CBT. In this study, we analysed the sequential effect of TD-CBT on post- treatment rumination and worry, anxiety/depression symptoms at 6-months and psychological and physical QoL at 12-months. We use data from PsicAP, a randomised clinical trial in the Primary Care (PC) setting, with 1061 participants randomised to TAU (treatment as usual) or TD-CBT+TAU. Path analyses using SEM were employed to test serial mediation models. Analyses indicated that TD-CBT exerts its long-term beneficial effects on QoL through a cascade of effects, whereby first the maladaptive cognitive processes of rumination and worry are reduced (post-treatment), then anxiety and depressive symptoms (6-months) and finally QoL is improved (12-months). This study provides longitudinal evidence on the mechanisms of change of TD-CBT in patients with anxiety and depression. It also highlights the importance of targeting transdiagnostic interventions towards early modification of negative repetitive thought processes as a critical pathway to long-term symptomatic and functional recovery.20252025-11-1520252025-01-0120252025-01-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/11268/16474reponame:ABACUS. Repositorio de Producción Científicainstname:Universidad Europea (UEM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:abacus.universidadeuropea.com:11268/164742026-06-11T12:41:27Z
dc.title.none.fl_str_mv Mechanisms of change in long-term transdiagnostic cognitive behavioural therapy: the sequential effect of rumination and worry on symptoms and quality of life
title Mechanisms of change in long-term transdiagnostic cognitive behavioural therapy: the sequential effect of rumination and worry on symptoms and quality of life
spellingShingle Mechanisms of change in long-term transdiagnostic cognitive behavioural therapy: the sequential effect of rumination and worry on symptoms and quality of life
Esteller Collado, Gabriel
Ciencias médicas
Psicología clínica
Psicología social
Goal 3: Ensure healthy lives and promote well-being for all at all ages
Goal 4: Quality education
Goal 5: Achieve gender equality and empower all women and girls
title_short Mechanisms of change in long-term transdiagnostic cognitive behavioural therapy: the sequential effect of rumination and worry on symptoms and quality of life
title_full Mechanisms of change in long-term transdiagnostic cognitive behavioural therapy: the sequential effect of rumination and worry on symptoms and quality of life
title_fullStr Mechanisms of change in long-term transdiagnostic cognitive behavioural therapy: the sequential effect of rumination and worry on symptoms and quality of life
title_full_unstemmed Mechanisms of change in long-term transdiagnostic cognitive behavioural therapy: the sequential effect of rumination and worry on symptoms and quality of life
title_sort Mechanisms of change in long-term transdiagnostic cognitive behavioural therapy: the sequential effect of rumination and worry on symptoms and quality of life
dc.creator.none.fl_str_mv Esteller Collado, Gabriel
Prieto Vila, Maider
Carpallo González, María
Antuña Camblor, Celia
Ruiz Rodríguez, Paloma
González Blanch, César
Moriana, Juan Antonio
Cano Vindel, Antonio
Muñoz Navarro, Roger
author Esteller Collado, Gabriel
author_facet Esteller Collado, Gabriel
Prieto Vila, Maider
Carpallo González, María
Antuña Camblor, Celia
Ruiz Rodríguez, Paloma
González Blanch, César
Moriana, Juan Antonio
Cano Vindel, Antonio
Muñoz Navarro, Roger
author_role author
author2 Prieto Vila, Maider
Carpallo González, María
Antuña Camblor, Celia
Ruiz Rodríguez, Paloma
González Blanch, César
Moriana, Juan Antonio
Cano Vindel, Antonio
Muñoz Navarro, Roger
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Ciencias médicas
Psicología clínica
Psicología social
Goal 3: Ensure healthy lives and promote well-being for all at all ages
Goal 4: Quality education
Goal 5: Achieve gender equality and empower all women and girls
topic Ciencias médicas
Psicología clínica
Psicología social
Goal 3: Ensure healthy lives and promote well-being for all at all ages
Goal 4: Quality education
Goal 5: Achieve gender equality and empower all women and girls
description Anxiety and depressive disorders are the most prevalent disorders worldwide and significantly impair quality of life (QoL). Transdiagnostic cognitive behavioural therapy (TD-CBT) is effective in treating these disorders and improving QoL, but its long-term mechanisms of change are poorly understood. Rumination and worry are key processes addressed by TD-CBT. In this study, we analysed the sequential effect of TD-CBT on post- treatment rumination and worry, anxiety/depression symptoms at 6-months and psychological and physical QoL at 12-months. We use data from PsicAP, a randomised clinical trial in the Primary Care (PC) setting, with 1061 participants randomised to TAU (treatment as usual) or TD-CBT+TAU. Path analyses using SEM were employed to test serial mediation models. Analyses indicated that TD-CBT exerts its long-term beneficial effects on QoL through a cascade of effects, whereby first the maladaptive cognitive processes of rumination and worry are reduced (post-treatment), then anxiety and depressive symptoms (6-months) and finally QoL is improved (12-months). This study provides longitudinal evidence on the mechanisms of change of TD-CBT in patients with anxiety and depression. It also highlights the importance of targeting transdiagnostic interventions towards early modification of negative repetitive thought processes as a critical pathway to long-term symptomatic and functional recovery.
publishDate 2025
dc.date.none.fl_str_mv 2025
2025-11-15
2025
2025-01-01
2025
2025-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/11268/16474
url https://hdl.handle.net/11268/16474
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:ABACUS. Repositorio de Producción Científica
instname:Universidad Europea (UEM)
instname_str Universidad Europea (UEM)
reponame_str ABACUS. Repositorio de Producción Científica
collection ABACUS. Repositorio de Producción Científica
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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