Could olfactory identification be a prognostic factor in detecting cognitive impairment risk in the elderly?
Abstract Aging contributes to the deterioration of the olfactory system in humans. Several studies indicate that the olfactory identifcation test alone may function as a screening test for olfactory dysfunction and they are more feasible to apply in clinical practice. Olfactory identifcation may be...
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2023 |
| País: | España |
| Institución: | Universidad Alfonso X el Sabio |
| Repositorio: | Repositorio Institucional de la Universidad Alfonso X el Sabio |
| Idioma: | inglés |
| OAI Identifier: | oai:archive.uax.com:20.500.12080/53466 |
| Acceso en línea: | https://hdl.handle.net/20.500.12080/53466 |
| Access Level: | acceso abierto |
| Palabra clave: | Envejecimiento Deterioro cognitivo |
| Sumario: | Abstract Aging contributes to the deterioration of the olfactory system in humans. Several studies indicate that the olfactory identifcation test alone may function as a screening test for olfactory dysfunction and they are more feasible to apply in clinical practice. Olfactory identifcation may be a predictor for cognitive impair ment. Multiple studies have considered the use of odor identifcation as a measure to identify the conversion from normality to mild cognitive impairment or demen tia. The objectives were (i) to elucidate the associations between cognitive status and olfactory identifcation performance in aging; (ii) understand the predictive value of olfactory capacity in identifying subjects with cognitive impairment risk; and (iii) to study how cogni tive status and olfactory identifcation relate with other variables of wellness in aging, such as functional capa bilities and clinical measures. For this purpose, a group of 149 participants (77.15±7.29 years; 73 women of 76.7±8 years and 76 men of 77.6±6.52 years) were recruited and were subjected to a ociodemographic questionnaire, a psychological screening tool of general cognitive status, an olfactory identifcation evaluation, and clinical measures. The participants were divided into groups based on their cutof scores of previous sci entifc reports about the Spanish version of Montreal Cognitive Assessment. Our results indicate an age associated decline in olfactory identifcation ability and intensity of odor perception. The predictive ability of olfactory identifcation scores for the risk of mild and severe impairment is around 80%. Olfactory identifca tion decreases with cognitive function. Performance in odor identifcation is associated with impairment of episodic memory and executive functions. These fnd ings further our current understanding of the association between cognition and olfaction, and support olfactory assessment in screening those at higher risk of dementia. |
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