Impact of Baseline Anemia in Patients Undergoing Transcatheter Aortic Valve Replacement
Transcatheter aortic valve replacement (TAVR) is currently the treatment of choice for patients aged ≥75 years with severe aortic stenosis. Preoperative anemia is present in a large proportion of patients and may increase the risk of post-procedural complications. The purpose of this prognostic syst...
| Autores: | , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2023 |
| País: | España |
| Institución: | Universitat Autònoma de Barcelona |
| Repositorio: | Dipòsit Digital de Documents de la UAB |
| Idioma: | inglés |
| OAI Identifier: | oai:ddd.uab.cat:300815 |
| Acceso en línea: | https://ddd.uab.cat/record/300815 https://dx.doi.org/urn:doi:10.3390/jcm12186025 |
| Access Level: | acceso abierto |
| Palabra clave: | TAVR Anemia Aortic stenosis Transcatheter aortic valve replacement |
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Impact of Baseline Anemia in Patients Undergoing Transcatheter Aortic Valve ReplacementA Prognostic Systematic Review and Meta-AnalysisJiménez Xarrié, Elena|||0000-0003-3567-0672Asmarats, Lluís|||0000-0002-3357-5834Roqué i Figuls, Marta|||0000-0003-0043-1364Millán, Xavier|||0000-0001-6519-4190Li, Chi Hion|||0000-0001-7556-3711Fernández-Peregrina, Estefanía|||0000-0002-3025-8251Sánchez-Ceña, Juan|||0000-0002-7913-7813Massó van Roessel, Albert|||0000-0003-1527-9019Maestre Hittinger, M. Luz|||0000-0002-9193-9325Paniagua, Pilar|||0000-0002-0215-1561Arzamendi, Dabit|||0000-0001-7543-5867TAVRAnemiaAortic stenosisTranscatheter aortic valve replacementTranscatheter aortic valve replacement (TAVR) is currently the treatment of choice for patients aged ≥75 years with severe aortic stenosis. Preoperative anemia is present in a large proportion of patients and may increase the risk of post-procedural complications. The purpose of this prognostic systematic review was to analyze the impact of baseline anemia on short- and mid-term outcomes following TAVR. A computerized search was performed on PubMed and Web of Science databases for studies published between January 2013 and December 2022. Primary outcomes were 30-day need for transfusion, acute renal failure, 30-day and mid-term mortality, and readmission during the first year post-TAVR. Data were analyzed via random effects model using inverse variance method with 95% confidence intervals. Eleven observational studies met our eligibility criteria and included a total of 12,588 patients. The prevalence of baseline anemia ranged between 39% and 72%, with no relevant sex differences. Patients with preprocedural anemia received more blood transfusions [OR: 2.95 (2.13-4.09)]), and exhibited increased rates of acute kidney injury [OR:1.74 (1.45-2.10)], short-term mortality [OR: 1.47 (1.07-2.01], and mid-term [OR: 1.89 (1.58-2.25)] mortality following TAVR compared with those without anemia. Baseline anemia determined an increased risk for blood transfusion, acute kidney injury, and short/mid-term mortality among TAVR recipients.Universitat Autònoma de Barcelona 22023-01-0120232023-01-01Article de revisióhttp://purl.org/coar/resource_type/c_dcae04bcVoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/300815https://dx.doi.org/urn:doi:10.3390/jcm12186025reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:3008152026-06-06T12:50:31Z |
| dc.title.none.fl_str_mv |
Impact of Baseline Anemia in Patients Undergoing Transcatheter Aortic Valve Replacement A Prognostic Systematic Review and Meta-Analysis |
| title |
Impact of Baseline Anemia in Patients Undergoing Transcatheter Aortic Valve Replacement |
| spellingShingle |
Impact of Baseline Anemia in Patients Undergoing Transcatheter Aortic Valve Replacement Jiménez Xarrié, Elena|||0000-0003-3567-0672 TAVR Anemia Aortic stenosis Transcatheter aortic valve replacement |
| title_short |
Impact of Baseline Anemia in Patients Undergoing Transcatheter Aortic Valve Replacement |
| title_full |
Impact of Baseline Anemia in Patients Undergoing Transcatheter Aortic Valve Replacement |
| title_fullStr |
Impact of Baseline Anemia in Patients Undergoing Transcatheter Aortic Valve Replacement |
| title_full_unstemmed |
Impact of Baseline Anemia in Patients Undergoing Transcatheter Aortic Valve Replacement |
| title_sort |
Impact of Baseline Anemia in Patients Undergoing Transcatheter Aortic Valve Replacement |
| dc.creator.none.fl_str_mv |
Jiménez Xarrié, Elena|||0000-0003-3567-0672 Asmarats, Lluís|||0000-0002-3357-5834 Roqué i Figuls, Marta|||0000-0003-0043-1364 Millán, Xavier|||0000-0001-6519-4190 Li, Chi Hion|||0000-0001-7556-3711 Fernández-Peregrina, Estefanía|||0000-0002-3025-8251 Sánchez-Ceña, Juan|||0000-0002-7913-7813 Massó van Roessel, Albert|||0000-0003-1527-9019 Maestre Hittinger, M. Luz|||0000-0002-9193-9325 Paniagua, Pilar|||0000-0002-0215-1561 Arzamendi, Dabit|||0000-0001-7543-5867 |
| author |
Jiménez Xarrié, Elena|||0000-0003-3567-0672 |
| author_facet |
Jiménez Xarrié, Elena|||0000-0003-3567-0672 Asmarats, Lluís|||0000-0002-3357-5834 Roqué i Figuls, Marta|||0000-0003-0043-1364 Millán, Xavier|||0000-0001-6519-4190 Li, Chi Hion|||0000-0001-7556-3711 Fernández-Peregrina, Estefanía|||0000-0002-3025-8251 Sánchez-Ceña, Juan|||0000-0002-7913-7813 Massó van Roessel, Albert|||0000-0003-1527-9019 Maestre Hittinger, M. Luz|||0000-0002-9193-9325 Paniagua, Pilar|||0000-0002-0215-1561 Arzamendi, Dabit|||0000-0001-7543-5867 |
| author_role |
author |
| author2 |
Asmarats, Lluís|||0000-0002-3357-5834 Roqué i Figuls, Marta|||0000-0003-0043-1364 Millán, Xavier|||0000-0001-6519-4190 Li, Chi Hion|||0000-0001-7556-3711 Fernández-Peregrina, Estefanía|||0000-0002-3025-8251 Sánchez-Ceña, Juan|||0000-0002-7913-7813 Massó van Roessel, Albert|||0000-0003-1527-9019 Maestre Hittinger, M. Luz|||0000-0002-9193-9325 Paniagua, Pilar|||0000-0002-0215-1561 Arzamendi, Dabit|||0000-0001-7543-5867 |
| author2_role |
author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Universitat Autònoma de Barcelona |
| dc.subject.none.fl_str_mv |
TAVR Anemia Aortic stenosis Transcatheter aortic valve replacement |
| topic |
TAVR Anemia Aortic stenosis Transcatheter aortic valve replacement |
| description |
Transcatheter aortic valve replacement (TAVR) is currently the treatment of choice for patients aged ≥75 years with severe aortic stenosis. Preoperative anemia is present in a large proportion of patients and may increase the risk of post-procedural complications. The purpose of this prognostic systematic review was to analyze the impact of baseline anemia on short- and mid-term outcomes following TAVR. A computerized search was performed on PubMed and Web of Science databases for studies published between January 2013 and December 2022. Primary outcomes were 30-day need for transfusion, acute renal failure, 30-day and mid-term mortality, and readmission during the first year post-TAVR. Data were analyzed via random effects model using inverse variance method with 95% confidence intervals. Eleven observational studies met our eligibility criteria and included a total of 12,588 patients. The prevalence of baseline anemia ranged between 39% and 72%, with no relevant sex differences. Patients with preprocedural anemia received more blood transfusions [OR: 2.95 (2.13-4.09)]), and exhibited increased rates of acute kidney injury [OR:1.74 (1.45-2.10)], short-term mortality [OR: 1.47 (1.07-2.01], and mid-term [OR: 1.89 (1.58-2.25)] mortality following TAVR compared with those without anemia. Baseline anemia determined an increased risk for blood transfusion, acute kidney injury, and short/mid-term mortality among TAVR recipients. |
| publishDate |
2023 |
| dc.date.none.fl_str_mv |
2 2023-01-01 2023 2023-01-01 |
| dc.type.none.fl_str_mv |
Article de revisió http://purl.org/coar/resource_type/c_dcae04bc VoR http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
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article |
| dc.identifier.none.fl_str_mv |
https://ddd.uab.cat/record/300815 https://dx.doi.org/urn:doi:10.3390/jcm12186025 |
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https://ddd.uab.cat/record/300815 https://dx.doi.org/urn:doi:10.3390/jcm12186025 |
| dc.language.none.fl_str_mv |
Inglés eng |
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Inglés |
| language |
eng |
| dc.rights.none.fl_str_mv |
open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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application/pdf |
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reponame:Dipòsit Digital de Documents de la UAB instname:Universitat Autònoma de Barcelona |
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Dipòsit Digital de Documents de la UAB |
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