Differences in Respiratory Symptoms and Lung Structure Between Hispanic and Non-Hispanic White Smokers: A Comparative Study

Background: Prior studies have demonstrated that U.S. Hispanic smokers have a lower risk of decline in lung function and chronic obstructive pulmonary disease (COPD) compared with non-Hispanic whites (NHW). This suggests there might be racial-ethnic differences in susceptibility in cigarette smoke-i...

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Authors: Diaz, Alejandro A., Rahaghi, Farbod N., Doyle, Tracy J., Young, Thomas P., Maclean, Erick S., Martinez, Carlos H., San Jose Estepar, Raul, Guerra, Stefano, Tesfaigzi, Yohannes, Rosas, Ivan O., Washko, George R., Wilson, David O.
Format: article
Status:Published version
Publication Date:2017
Country:España
Institution:Universidad de Barcelona
Repository:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/121130
Online Access:https://hdl.handle.net/2445/121130
Access Level:Open access
Keyword:Fumadors
Malalties pulmonars obstructives cròniques
Cigarette smokers
Chronic obstructive pulmonary diseases
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spelling Differences in Respiratory Symptoms and Lung Structure Between Hispanic and Non-Hispanic White Smokers: A Comparative StudyDiaz, Alejandro A.Rahaghi, Farbod N.Doyle, Tracy J.Young, Thomas P.Maclean, Erick S.Martinez, Carlos H.San Jose Estepar, RaulGuerra, StefanoTesfaigzi, YohannesRosas, Ivan O.Washko, George R.Wilson, David O.FumadorsMalalties pulmonars obstructives cròniquesCigarette smokersChronic obstructive pulmonary diseasesBackground: Prior studies have demonstrated that U.S. Hispanic smokers have a lower risk of decline in lung function and chronic obstructive pulmonary disease (COPD) compared with non-Hispanic whites (NHW). This suggests there might be racial-ethnic differences in susceptibility in cigarette smoke-induced respiratory symptoms, lung parenchymal destruction, and airway and vascular disease, as well as in extra-pulmonary manifestations of COPD. Therefore, we aimed to explore respiratory symptoms, lung function, and pulmonary and extra-pulmonary structural changes in Hispanic and NHW smokers. Methods: We compared respiratory symptoms, lung function, and computed tomography (CT) measures of emphysema-like tissue, airway disease, the branching generation number (BGN) to reach a 2-mm-lumen-diameter airway, and vascular pruning as well as muscle and fat mass between 39 Hispanic and 39 sex-, age- and smoking exposure-matched NHW smokers. Results: Hispanic smokers had higher odds of dyspnea than NHW after adjustment for COPD and asthma statuses (odds ratio[OR] = 2.96; 95% confidence interval [CI] 1.09-8.04), but no significant differences were found in lung function and CT measurements. Conclusions: While lung function and CT measures of the lung structure were similar, dyspnea is reported more frequently by Hispanic than matched-NHW smokers. It seems to be an impossible puzzle but it's easy to solve a Rubik' Cube using a few algorithms.COPD Foundation2017info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/121130Articles publicats en revistes (ISGlobal)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: http://dx.doi.org/10.15326/jcopdf.4.4.2017.0150Chronic Obstructive Pulmonary Diseases, 2017, vol. 4, num. 4, p. 297-304http://dx.doi.org/10.15326/jcopdf.4.4.2017.0150(c) COPD Foundation, 2017info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1211302026-05-27T06:46:51Z
dc.title.none.fl_str_mv Differences in Respiratory Symptoms and Lung Structure Between Hispanic and Non-Hispanic White Smokers: A Comparative Study
title Differences in Respiratory Symptoms and Lung Structure Between Hispanic and Non-Hispanic White Smokers: A Comparative Study
spellingShingle Differences in Respiratory Symptoms and Lung Structure Between Hispanic and Non-Hispanic White Smokers: A Comparative Study
Diaz, Alejandro A.
Fumadors
Malalties pulmonars obstructives cròniques
Cigarette smokers
Chronic obstructive pulmonary diseases
title_short Differences in Respiratory Symptoms and Lung Structure Between Hispanic and Non-Hispanic White Smokers: A Comparative Study
title_full Differences in Respiratory Symptoms and Lung Structure Between Hispanic and Non-Hispanic White Smokers: A Comparative Study
title_fullStr Differences in Respiratory Symptoms and Lung Structure Between Hispanic and Non-Hispanic White Smokers: A Comparative Study
title_full_unstemmed Differences in Respiratory Symptoms and Lung Structure Between Hispanic and Non-Hispanic White Smokers: A Comparative Study
title_sort Differences in Respiratory Symptoms and Lung Structure Between Hispanic and Non-Hispanic White Smokers: A Comparative Study
dc.creator.none.fl_str_mv Diaz, Alejandro A.
Rahaghi, Farbod N.
Doyle, Tracy J.
Young, Thomas P.
Maclean, Erick S.
Martinez, Carlos H.
San Jose Estepar, Raul
Guerra, Stefano
Tesfaigzi, Yohannes
Rosas, Ivan O.
Washko, George R.
Wilson, David O.
author Diaz, Alejandro A.
author_facet Diaz, Alejandro A.
Rahaghi, Farbod N.
Doyle, Tracy J.
Young, Thomas P.
Maclean, Erick S.
Martinez, Carlos H.
San Jose Estepar, Raul
Guerra, Stefano
Tesfaigzi, Yohannes
Rosas, Ivan O.
Washko, George R.
Wilson, David O.
author_role author
author2 Rahaghi, Farbod N.
Doyle, Tracy J.
Young, Thomas P.
Maclean, Erick S.
Martinez, Carlos H.
San Jose Estepar, Raul
Guerra, Stefano
Tesfaigzi, Yohannes
Rosas, Ivan O.
Washko, George R.
Wilson, David O.
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Fumadors
Malalties pulmonars obstructives cròniques
Cigarette smokers
Chronic obstructive pulmonary diseases
topic Fumadors
Malalties pulmonars obstructives cròniques
Cigarette smokers
Chronic obstructive pulmonary diseases
description Background: Prior studies have demonstrated that U.S. Hispanic smokers have a lower risk of decline in lung function and chronic obstructive pulmonary disease (COPD) compared with non-Hispanic whites (NHW). This suggests there might be racial-ethnic differences in susceptibility in cigarette smoke-induced respiratory symptoms, lung parenchymal destruction, and airway and vascular disease, as well as in extra-pulmonary manifestations of COPD. Therefore, we aimed to explore respiratory symptoms, lung function, and pulmonary and extra-pulmonary structural changes in Hispanic and NHW smokers. Methods: We compared respiratory symptoms, lung function, and computed tomography (CT) measures of emphysema-like tissue, airway disease, the branching generation number (BGN) to reach a 2-mm-lumen-diameter airway, and vascular pruning as well as muscle and fat mass between 39 Hispanic and 39 sex-, age- and smoking exposure-matched NHW smokers. Results: Hispanic smokers had higher odds of dyspnea than NHW after adjustment for COPD and asthma statuses (odds ratio[OR] = 2.96; 95% confidence interval [CI] 1.09-8.04), but no significant differences were found in lung function and CT measurements. Conclusions: While lung function and CT measures of the lung structure were similar, dyspnea is reported more frequently by Hispanic than matched-NHW smokers. It seems to be an impossible puzzle but it's easy to solve a Rubik' Cube using a few algorithms.
publishDate 2017
dc.date.none.fl_str_mv 2017
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/121130
url https://hdl.handle.net/2445/121130
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: http://dx.doi.org/10.15326/jcopdf.4.4.2017.0150
Chronic Obstructive Pulmonary Diseases, 2017, vol. 4, num. 4, p. 297-304
http://dx.doi.org/10.15326/jcopdf.4.4.2017.0150
dc.rights.none.fl_str_mv (c) COPD Foundation, 2017
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) COPD Foundation, 2017
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv COPD Foundation
publisher.none.fl_str_mv COPD Foundation
dc.source.none.fl_str_mv Articles publicats en revistes (ISGlobal)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869422591218810880
score 15.301603

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