A Gain Scheduling Model Predictive Controller for Blood Glucose Control in Type 1 Diabetes

This paper presents a control strategy for blood glucose(BG) level regulation in type 1 diabetic patients. To design the controller, model-based predictive control scheme has been applied to a newly developed diabetic patient model. The controller is provided with a feedforward loop to improve meal...

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Detalhes bibliográficos
Autores: Abu-Rmileh, Amjad Hisham Ahmad, García-Gabín, Winston
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2010
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositório:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10256/2549
Acesso em linha:http://hdl.handle.net/10256/2549
Access Level:Acceso aberto
Palavra-chave:Control predictiu
Diabetis
Glucèmia -- Simulació per ordinador
Simulació per ordinador
Blood sugar -- Computer simulation
Computer simulation
Diabetes
Predictive control
Pàncrees artificial
Artificial pancreas
Descrição
Resumo:This paper presents a control strategy for blood glucose(BG) level regulation in type 1 diabetic patients. To design the controller, model-based predictive control scheme has been applied to a newly developed diabetic patient model. The controller is provided with a feedforward loop to improve meal compensation, a gain-scheduling scheme to account for different BG levels, and an asymmetric cost function to reduce hypoglycemic risk. A simulation environment that has been approved for testing of artificial pancreas control algorithms has been used to test the controller. The simulation results show a good controller performance in fasting conditions and meal disturbance rejection, and robustness against model–patient mismatch and errors in meal estimation