Factors associated with severe sepsis or septic shock in complicated pyelonephritis.

Severe sepsis or septic shock are the main factors influencing the prognosis of acute pyelonephritis (APN). Our aim was to analyze factors associated with the development of severe sepsis or septic shock in a large sample of patients with acute complicated pyelonephritis (ACPN).This prospective obse...

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Detalhes bibliográficos
Autores: Ruiz-Mesa, Juan D, Marquez-Gomez, Ignacio, Sena, Gabriel, Buonaiuto, Veronica A, Mora-Ordoñez, Juan, Salido, Manuel, Plata Ciézar, Antonio, Valiente-De Santis, Lucía, Mediavilla, Concepción, Colmenero, Juan D
Formato: artículo
Fecha de publicación:2017
País:España
Recursos:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/17275
Acesso em linha:http://hdl.handle.net/20.500.12105/17275
Access Level:acceso abierto
Palavra-chave:Acute Disease
Aged
Female
Hospitalization
Humans
Logistic Models
Male
Middle Aged
Multivariate Analysis
Prevalence
Prospective Studies
Pyelonephritis
Risk Factors
Sepsis
Shock, Septic
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oai_identifier_str oai:repisalud.isciii.es:20.500.12105/17275
network_acronym_str ES
network_name_str España
repository_id_str
spelling Factors associated with severe sepsis or septic shock in complicated pyelonephritis.Ruiz-Mesa, Juan DMarquez-Gomez, IgnacioSena, GabrielBuonaiuto, Veronica AMora-Ordoñez, JuanSalido, ManuelPlata Ciézar, AntonioValiente-De Santis, LucíaMediavilla, ConcepciónColmenero, Juan DAcute DiseaseAgedFemaleHospitalizationHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisPrevalenceProspective StudiesPyelonephritisRisk FactorsSepsisShock, SepticSevere sepsis or septic shock are the main factors influencing the prognosis of acute pyelonephritis (APN). Our aim was to analyze factors associated with the development of severe sepsis or septic shock in a large sample of patients with acute complicated pyelonephritis (ACPN).This prospective observational study comprised 1507 consecutive patients aged 14 years or older who were admitted to a tertiary care hospital because of ACPN between 1997 and 2015. Covariates associated in univariate analysis with severe sepsis or septic shock were then analyzed by multivariate logistic regression.Of the 1507 patients, 423 (28.1%) fulfilled the criteria for severe sepsis or septic shock at the time of admission. Crude and attributable mortality at 30 days were 17.7% and 11.7% in patients with severe sepsis or septic shock versus 1.7% and 0.6% in patients without severe sepsis or septic shock, P  65 years, urinary instrumentation in the previous 2 weeks, the lack of mictional syndrome or costovertebral tenderness, an ectasia ≥ grade II, and bacteremia were independent risk factors associated with severe sepsis or septic shock.The prevalence of severe sepsis and septic shock in patients with ACPN is high. Some factors associated with severe sepsis are easy to identify in any emergency department. The information provided here could be useful when deciding which patients should be admitted to receive immediate treatment.20242024-01-2320172017-01-0120172017-01-01research articlehttp://purl.org/coar/resource_type/c_2df8fbb1VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articlehttp://hdl.handle.net/20.500.12105/17275reponame:Repisaludinstname:Instituto de Salud Carlos III (ISCIII)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessoai:repisalud.isciii.es:20.500.12105/172752026-06-12T12:43:37Z
dc.title.none.fl_str_mv Factors associated with severe sepsis or septic shock in complicated pyelonephritis.
title Factors associated with severe sepsis or septic shock in complicated pyelonephritis.
spellingShingle Factors associated with severe sepsis or septic shock in complicated pyelonephritis.
Ruiz-Mesa, Juan D
Acute Disease
Aged
Female
Hospitalization
Humans
Logistic Models
Male
Middle Aged
Multivariate Analysis
Prevalence
Prospective Studies
Pyelonephritis
Risk Factors
Sepsis
Shock, Septic
title_short Factors associated with severe sepsis or septic shock in complicated pyelonephritis.
title_full Factors associated with severe sepsis or septic shock in complicated pyelonephritis.
title_fullStr Factors associated with severe sepsis or septic shock in complicated pyelonephritis.
title_full_unstemmed Factors associated with severe sepsis or septic shock in complicated pyelonephritis.
title_sort Factors associated with severe sepsis or septic shock in complicated pyelonephritis.
dc.creator.none.fl_str_mv Ruiz-Mesa, Juan D
Marquez-Gomez, Ignacio
Sena, Gabriel
Buonaiuto, Veronica A
Mora-Ordoñez, Juan
Salido, Manuel
Plata Ciézar, Antonio
Valiente-De Santis, Lucía
Mediavilla, Concepción
Colmenero, Juan D
author Ruiz-Mesa, Juan D
author_facet Ruiz-Mesa, Juan D
Marquez-Gomez, Ignacio
Sena, Gabriel
Buonaiuto, Veronica A
Mora-Ordoñez, Juan
Salido, Manuel
Plata Ciézar, Antonio
Valiente-De Santis, Lucía
Mediavilla, Concepción
Colmenero, Juan D
author_role author
author2 Marquez-Gomez, Ignacio
Sena, Gabriel
Buonaiuto, Veronica A
Mora-Ordoñez, Juan
Salido, Manuel
Plata Ciézar, Antonio
Valiente-De Santis, Lucía
Mediavilla, Concepción
Colmenero, Juan D
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Acute Disease
Aged
Female
Hospitalization
Humans
Logistic Models
Male
Middle Aged
Multivariate Analysis
Prevalence
Prospective Studies
Pyelonephritis
Risk Factors
Sepsis
Shock, Septic
topic Acute Disease
Aged
Female
Hospitalization
Humans
Logistic Models
Male
Middle Aged
Multivariate Analysis
Prevalence
Prospective Studies
Pyelonephritis
Risk Factors
Sepsis
Shock, Septic
description Severe sepsis or septic shock are the main factors influencing the prognosis of acute pyelonephritis (APN). Our aim was to analyze factors associated with the development of severe sepsis or septic shock in a large sample of patients with acute complicated pyelonephritis (ACPN).This prospective observational study comprised 1507 consecutive patients aged 14 years or older who were admitted to a tertiary care hospital because of ACPN between 1997 and 2015. Covariates associated in univariate analysis with severe sepsis or septic shock were then analyzed by multivariate logistic regression.Of the 1507 patients, 423 (28.1%) fulfilled the criteria for severe sepsis or septic shock at the time of admission. Crude and attributable mortality at 30 days were 17.7% and 11.7% in patients with severe sepsis or septic shock versus 1.7% and 0.6% in patients without severe sepsis or septic shock, P  65 years, urinary instrumentation in the previous 2 weeks, the lack of mictional syndrome or costovertebral tenderness, an ectasia ≥ grade II, and bacteremia were independent risk factors associated with severe sepsis or septic shock.The prevalence of severe sepsis and septic shock in patients with ACPN is high. Some factors associated with severe sepsis are easy to identify in any emergency department. The information provided here could be useful when deciding which patients should be admitted to receive immediate treatment.
publishDate 2017
dc.date.none.fl_str_mv 2017
2017-01-01
2017
2017-01-01
2024
2024-01-23
dc.type.none.fl_str_mv research article
http://purl.org/coar/resource_type/c_2df8fbb1
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12105/17275
url http://hdl.handle.net/20.500.12105/17275
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repisalud
instname:Instituto de Salud Carlos III (ISCIII)
instname_str Instituto de Salud Carlos III (ISCIII)
reponame_str Repisalud
collection Repisalud
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869422528580026368
score 15,812429

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