Estimation of the epidemiological burden of human papillomavirus-related cancers and nonmalignant diseases in men in Europe: a review

Background: The role of human papillomavirus (HPV) in malignant and non-malignant genital diseases in women is well known and the corresponding epidemiological burden has been widely described. However, less is known about the role of HPV in anal, penile and head and neck cancer, and the burden of m...

ver descrição completa

Detalhes bibliográficos
Autores: Hartwig, Susanne, Syrjänen, Stina, Dominiak-Felden, Géraldine, Brotons, Maria, Castellsagué, Xavier
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2012
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositório:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/126558
Acesso em linha:https://hdl.handle.net/2445/126558
Access Level:Acceso aberto
Palavra-chave:Papil·lomavirus
Epidemiologia
Papillomaviruses
Epidemiology
id ES_e386f1ec4e5c740f3bef415ba95ec5b3
oai_identifier_str oai:recercat.cat:2445/126558
network_acronym_str ES
network_name_str España
repository_id_str
spelling Estimation of the epidemiological burden of human papillomavirus-related cancers and nonmalignant diseases in men in Europe: a reviewHartwig, SusanneSyrjänen, StinaDominiak-Felden, GéraldineBrotons, MariaCastellsagué, XavierPapil·lomavirusEpidemiologiaPapillomavirusesEpidemiologyBackground: The role of human papillomavirus (HPV) in malignant and non-malignant genital diseases in women is well known and the corresponding epidemiological burden has been widely described. However, less is known about the role of HPV in anal, penile and head and neck cancer, and the burden of malignant and non-malignant HPV-related diseases in men. The objective of this review is to estimate the epidemiological burden of HPV-related cancers and non-malignant diseases in men in Europe. Methods: The annual number of new HPV-related cancers in men in Europe was estimated using Eurostat population data and applying cancer incidence rates published by the International Agency for Research on Cancer. The number of cancer cases attributable to HPV, and specifically to HPV16/18, was calculated based on the most relevant prevalence estimates. The annual number of new cases of genital warts was calculated from the most robust European studies; and latest HPV6/11 prevalence estimates were then applied. A literature review was also performed to retrieve exhaustive data on HPV infection at all anatomical sites under study, as well as incidence and prevalence of external genital warts, recurrent respiratory papillomatosis and HPV-related cancer trends in men in Europe. Results: A total of 72, 694 new cancer cases at HPV-related anatomical sites were estimated to occur each year in men in Europe. 17,403 of these cancer cases could be attributable to HPV, with 15,497 of them specifically attributable to HPV16/18. In addition, between 286,682 and 325,722 new cases of genital warts attributable to HPV6/11 were estimated to occur annually in men in Europe. Conclusions: The overall estimated epidemiological burden of HPV-related cancers and non-malignant diseases is high in men in Europe. Approximately 30% of all new cancer cases attributable to HPV16/18 that occur yearly in Europe were estimated to occur in men. As in women, the vast majority of HPV-positive cancer in men is related to HPV16/18, while almost all HPV-related non-malignant diseases are due to HPV6/11. A substantial number of these malignant and non-malignant diseases may potentially be prevented by quadrivalent HPV vaccination.BioMed Central2018201820122018info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion18 p.application/pdfhttps://hdl.handle.net/2445/126558Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: https://doi.org/10.1186/1471-2407-12-30BMC Cancer, 2012, vol. 12, num. 30https://doi.org/10.1186/1471-2407-12-30cc by (c) Hartwig et al., 2012http://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:recercat.cat:2445/1265582026-05-29T05:05:01Z
dc.title.none.fl_str_mv Estimation of the epidemiological burden of human papillomavirus-related cancers and nonmalignant diseases in men in Europe: a review
title Estimation of the epidemiological burden of human papillomavirus-related cancers and nonmalignant diseases in men in Europe: a review
spellingShingle Estimation of the epidemiological burden of human papillomavirus-related cancers and nonmalignant diseases in men in Europe: a review
Hartwig, Susanne
Papil·lomavirus
Epidemiologia
Papillomaviruses
Epidemiology
title_short Estimation of the epidemiological burden of human papillomavirus-related cancers and nonmalignant diseases in men in Europe: a review
title_full Estimation of the epidemiological burden of human papillomavirus-related cancers and nonmalignant diseases in men in Europe: a review
title_fullStr Estimation of the epidemiological burden of human papillomavirus-related cancers and nonmalignant diseases in men in Europe: a review
title_full_unstemmed Estimation of the epidemiological burden of human papillomavirus-related cancers and nonmalignant diseases in men in Europe: a review
title_sort Estimation of the epidemiological burden of human papillomavirus-related cancers and nonmalignant diseases in men in Europe: a review
dc.creator.none.fl_str_mv Hartwig, Susanne
Syrjänen, Stina
Dominiak-Felden, Géraldine
Brotons, Maria
Castellsagué, Xavier
author Hartwig, Susanne
author_facet Hartwig, Susanne
Syrjänen, Stina
Dominiak-Felden, Géraldine
Brotons, Maria
Castellsagué, Xavier
author_role author
author2 Syrjänen, Stina
Dominiak-Felden, Géraldine
Brotons, Maria
Castellsagué, Xavier
author2_role author
author
author
author
dc.subject.none.fl_str_mv Papil·lomavirus
Epidemiologia
Papillomaviruses
Epidemiology
topic Papil·lomavirus
Epidemiologia
Papillomaviruses
Epidemiology
description Background: The role of human papillomavirus (HPV) in malignant and non-malignant genital diseases in women is well known and the corresponding epidemiological burden has been widely described. However, less is known about the role of HPV in anal, penile and head and neck cancer, and the burden of malignant and non-malignant HPV-related diseases in men. The objective of this review is to estimate the epidemiological burden of HPV-related cancers and non-malignant diseases in men in Europe. Methods: The annual number of new HPV-related cancers in men in Europe was estimated using Eurostat population data and applying cancer incidence rates published by the International Agency for Research on Cancer. The number of cancer cases attributable to HPV, and specifically to HPV16/18, was calculated based on the most relevant prevalence estimates. The annual number of new cases of genital warts was calculated from the most robust European studies; and latest HPV6/11 prevalence estimates were then applied. A literature review was also performed to retrieve exhaustive data on HPV infection at all anatomical sites under study, as well as incidence and prevalence of external genital warts, recurrent respiratory papillomatosis and HPV-related cancer trends in men in Europe. Results: A total of 72, 694 new cancer cases at HPV-related anatomical sites were estimated to occur each year in men in Europe. 17,403 of these cancer cases could be attributable to HPV, with 15,497 of them specifically attributable to HPV16/18. In addition, between 286,682 and 325,722 new cases of genital warts attributable to HPV6/11 were estimated to occur annually in men in Europe. Conclusions: The overall estimated epidemiological burden of HPV-related cancers and non-malignant diseases is high in men in Europe. Approximately 30% of all new cancer cases attributable to HPV16/18 that occur yearly in Europe were estimated to occur in men. As in women, the vast majority of HPV-positive cancer in men is related to HPV16/18, while almost all HPV-related non-malignant diseases are due to HPV6/11. A substantial number of these malignant and non-malignant diseases may potentially be prevented by quadrivalent HPV vaccination.
publishDate 2012
dc.date.none.fl_str_mv 2012
2018
2018
2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/126558
url https://hdl.handle.net/2445/126558
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.1186/1471-2407-12-30
BMC Cancer, 2012, vol. 12, num. 30
https://doi.org/10.1186/1471-2407-12-30
dc.rights.none.fl_str_mv cc by (c) Hartwig et al., 2012
http://creativecommons.org/licenses/by/3.0/es/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc by (c) Hartwig et al., 2012
http://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 18 p.
application/pdf
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869422509400522752
score 15,811543

Registros relacionados