Functional connexion of bacterioferritin in antibiotic production and morphological differentiation in Streptomyces coelicolor

Several two-component systems of Streptomyces coelicolor, a model organism used for studying antibiotic production in Streptomyces, affect the expression of the bfr (SCO2113) gene that encodes a bacterioferritin, a protein involved in iron storage. In this work, we have studied the effect of the del...

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Detalhes bibliográficos
Autores: García-Martín, Javier, García-Abad, Laura, Santamaría, Ramón I., Díaz, Margarita
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/371918
Acesso em linha:http://hdl.handle.net/10261/371918
https://api.elsevier.com/content/abstract/scopus_id/85201978649
Access Level:acceso abierto
Palavra-chave:Streptomyces
Antibiotic production
Bacterioferritin
Iron
Two-component systems
Descrição
Resumo:Several two-component systems of Streptomyces coelicolor, a model organism used for studying antibiotic production in Streptomyces, affect the expression of the bfr (SCO2113) gene that encodes a bacterioferritin, a protein involved in iron storage. In this work, we have studied the effect of the deletion mutant ∆bfr in S. coelicolor.