Intergenerational effects of maternal childhood maltreatment on newborns' stress regulation: The role of maternal depressive symptoms

Background: Maternal childhood maltreatment (CM) has been repeatedly associated with negative offspring's emotional outcomes. The dysregulation of the Hypothalamic-Pituitary-Adrenal (HPA) axis has emerged as the main underlying physiological mechanism. Objective: To explore the association betw...

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Detalles Bibliográficos
Autores: San Martín González, Nerea, Moya Higueras, Jorge, Eixarch, Elisenda, Castro Quintas, Águeda, Marques Feixa, Laia, Crispi, Fátima, Daura-Corral, Maria, Fuente-Tomás, Lorena de la, Monteserín, José Luís, García-Portilla, María Paz, Fañanás Saura, Lourdes
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Universitat de Lleida (UdL)
Repositorio:Repositori Obert UdL
OAI Identifier:oai:repositori.udl.cat:10459.1/466452
Acceso en línea:https://doi.org/10.1016/j.chiabu.2024.106968
https://hdl.handle.net/10459.1/466452
Access Level:acceso abierto
Palabra clave:Maternal childhood maltreatment
Intergenerational
Stress regulation
Behavior
Cortisol reactivity
Descripción
Sumario:Background: Maternal childhood maltreatment (CM) has been repeatedly associated with negative offspring's emotional outcomes. The dysregulation of the Hypothalamic-Pituitary-Adrenal (HPA) axis has emerged as the main underlying physiological mechanism. Objective: To explore the association between maternal CM and newborns' physiological and neurobehavioral stress responses, considering the role of perinatal maternal depression and bonding. Participants and setting: 150 healthy women were followed throughout pregnancy. 79 mother- infant dyads were included in the final analyses. Maternal CM was evaluated using the Childhood Trauma Questionnaire and depressive symptoms by the Edinburgh Postnatal Depression Scale (EPDS) at each trimester. At 7 weeks postpartum, the EPDS and the Postpartum Bonding Questionnaire were administered. Newborns' behavioral responses were assessed using 'States Organization' (SO) and 'States Regulation' (SR) subdomains of the Neonatal Behavioral Assessment Scale (NBAS). Newborns' salivary samples were collected before and after the NBAS to study cortisol reactivity. Methods: A cross-lagged panel model was employed.

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