Validated method for polystyrene nanoplastic separation in aqueous matrices by asymmetric-flow field flow fraction coupled to MALS and UV-Vis detectors

Plastics with nanosize (nanoplastics, NPLs) must be characterized, since they can be toxic or act as carriers of organic and inorganic pollutants, but there is a lack of reference materials and validated methods in the nanosize range. Therefore, this study has focused on the development and validati...

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Detalles Bibliográficos
Autores: Valido, Iris H.|||0000-0002-4037-1223, Fuentes Cebrian, Victor|||0000-0002-5634-0448, Hernández Bonilla, Alba|||0000-0001-6938-1233, Valiente, Manuel|||0000-0003-0766-9922, López-Mesas, Montserrat|||0000-0002-4470-0194
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:283179
Acceso en línea:https://ddd.uab.cat/record/283179
https://dx.doi.org/urn:doi:10.1007/s00604-023-05851-7
Access Level:acceso abierto
Palabra clave:AF4-MALS-UV
Nanoplastics
Polystyrene
Reference standards
Spheres
Validation
Water
Polystyrenes
Microplastics
Plastics
Descripción
Sumario:Plastics with nanosize (nanoplastics, NPLs) must be characterized, since they can be toxic or act as carriers of organic and inorganic pollutants, but there is a lack of reference materials and validated methods in the nanosize range. Therefore, this study has focused on the development and validation of a separation and size characterization methodology of polystyrene latex nanospheres, by using an asymmetric-flow field flow fraction system coupled to multi-angle light scattering and ultraviolet-visible detectors (AF4-MALS-UV). Hence, this work presents a fully validated methodology in the particle size range 30 to 490 nm, with bias between 95 and 109%, precision between 1 and 18%, LOD and LOQ below 0.2 and 0.3 µg respectively, except for 30-nm standard, for both detectors, and showing stable results for 100 analyses.