Normalization of creatine kinase values in a case of rhabdomyolysis during daptomycin treatment

A 41-year-old woman presented in the Emergency Department with suspected compartment syndrome of lower left leg (creatine kinase [CK]: 12,502 IU/L, Cr: 4.31 mg/dL). Fasciotomy of the four limb compartments was conducted. By day 2, the patient presented oliguria during previous 24 h, so daily intermi...

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Autores: Ferrández, Olivia|||0000-0003-0146-6366, Urbina, Olatz, Luque, Sònia, Espona, Mercè|||0009-0004-5982-1417, Berenguer, Nuria, Grau, Santiago|||0000-0002-8428-1836
Tipo de recurso: artículo
Fecha de publicación:2013
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:184924
Acceso en línea:https://ddd.uab.cat/record/184924
https://dx.doi.org/urn:doi:10.4103/0253-7613.108321
Access Level:acceso abierto
Palabra clave:Creatine kinase
Daptomycin
Rhabdomyolysis
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spelling Normalization of creatine kinase values in a case of rhabdomyolysis during daptomycin treatmentFerrández, Olivia|||0000-0003-0146-6366Urbina, OlatzLuque, SòniaEspona, Mercè|||0009-0004-5982-1417Berenguer, NuriaGrau, Santiago|||0000-0002-8428-1836Creatine kinaseDaptomycinRhabdomyolysisA 41-year-old woman presented in the Emergency Department with suspected compartment syndrome of lower left leg (creatine kinase [CK]: 12,502 IU/L, Cr: 4.31 mg/dL). Fasciotomy of the four limb compartments was conducted. By day 2, the patient presented oliguria during previous 24 h, so daily intermittent dialysis was carried out. On day 12, the patient presented an episode of bacteremia due to Staphylococcus hominis. Treatment with vancomycin was initiated and was changed after 4 days to daptomycin due to unsatisfactory clinical progression (6 mg/kg every 48 h, according to renal function and patient's weight) (CK: 2,972 IU/L). After 15 days of treatment, the dose of daptomycin was increased to 6 mg/kg every 24 h (CrCL: 46 mL/min, CK: 83 IU/L). The antibiotic was continued for another 4 days. Fourteen days later, the patient was discharged (CK: 26 IU/L). Daptomycin could be prescribed in some patients with elevated CK values. A cut-off value of baseline CK for use of daptomycin needs to be determined.Universitat Autònoma de Barcelona 22013-01-0120132013-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/184924https://dx.doi.org/urn:doi:10.4103/0253-7613.108321reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra, i la creació d'obres derivades, sempre que no sigui amb finalitats comercials i que es distribueixin sota la mateixa llicència que regula l'obra original. Cal que es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:1849242026-06-06T12:50:31Z
dc.title.none.fl_str_mv Normalization of creatine kinase values in a case of rhabdomyolysis during daptomycin treatment
title Normalization of creatine kinase values in a case of rhabdomyolysis during daptomycin treatment
spellingShingle Normalization of creatine kinase values in a case of rhabdomyolysis during daptomycin treatment
Ferrández, Olivia|||0000-0003-0146-6366
Creatine kinase
Daptomycin
Rhabdomyolysis
title_short Normalization of creatine kinase values in a case of rhabdomyolysis during daptomycin treatment
title_full Normalization of creatine kinase values in a case of rhabdomyolysis during daptomycin treatment
title_fullStr Normalization of creatine kinase values in a case of rhabdomyolysis during daptomycin treatment
title_full_unstemmed Normalization of creatine kinase values in a case of rhabdomyolysis during daptomycin treatment
title_sort Normalization of creatine kinase values in a case of rhabdomyolysis during daptomycin treatment
dc.creator.none.fl_str_mv Ferrández, Olivia|||0000-0003-0146-6366
Urbina, Olatz
Luque, Sònia
Espona, Mercè|||0009-0004-5982-1417
Berenguer, Nuria
Grau, Santiago|||0000-0002-8428-1836
author Ferrández, Olivia|||0000-0003-0146-6366
author_facet Ferrández, Olivia|||0000-0003-0146-6366
Urbina, Olatz
Luque, Sònia
Espona, Mercè|||0009-0004-5982-1417
Berenguer, Nuria
Grau, Santiago|||0000-0002-8428-1836
author_role author
author2 Urbina, Olatz
Luque, Sònia
Espona, Mercè|||0009-0004-5982-1417
Berenguer, Nuria
Grau, Santiago|||0000-0002-8428-1836
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universitat Autònoma de Barcelona
dc.subject.none.fl_str_mv Creatine kinase
Daptomycin
Rhabdomyolysis
topic Creatine kinase
Daptomycin
Rhabdomyolysis
description A 41-year-old woman presented in the Emergency Department with suspected compartment syndrome of lower left leg (creatine kinase [CK]: 12,502 IU/L, Cr: 4.31 mg/dL). Fasciotomy of the four limb compartments was conducted. By day 2, the patient presented oliguria during previous 24 h, so daily intermittent dialysis was carried out. On day 12, the patient presented an episode of bacteremia due to Staphylococcus hominis. Treatment with vancomycin was initiated and was changed after 4 days to daptomycin due to unsatisfactory clinical progression (6 mg/kg every 48 h, according to renal function and patient's weight) (CK: 2,972 IU/L). After 15 days of treatment, the dose of daptomycin was increased to 6 mg/kg every 24 h (CrCL: 46 mL/min, CK: 83 IU/L). The antibiotic was continued for another 4 days. Fourteen days later, the patient was discharged (CK: 26 IU/L). Daptomycin could be prescribed in some patients with elevated CK values. A cut-off value of baseline CK for use of daptomycin needs to be determined.
publishDate 2013
dc.date.none.fl_str_mv 2
2013-01-01
2013
2013-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://ddd.uab.cat/record/184924
https://dx.doi.org/urn:doi:10.4103/0253-7613.108321
url https://ddd.uab.cat/record/184924
https://dx.doi.org/urn:doi:10.4103/0253-7613.108321
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by-nc-sa/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by-nc-sa/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
reponame_str Dipòsit Digital de Documents de la UAB
collection Dipòsit Digital de Documents de la UAB
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repository.mail.fl_str_mv
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