Hydroxymethylfurfural determination in cereal and insect bars by high-performance liquid chromatography-mass spectrometry employing a functionalized mesostructured silica as sorbent in solid-phase extraction

In this work a new method for the determination of 5-hydroxymethylfurfural (HMF) in cereal and insect bars has been developed and validated. The method consisted of a solid-liquid extraction (SLE) followed by a solid phase extraction (SPE), employing functionalized mesostructured silica as sorbent,...

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Detalhes bibliográficos
Autores: González, Lorena, Morante-Zarcero, Sonia, Pérez-Quintanilla, Damián, Sierra, Isabel
Tipo de documento: artigo
Data de publicação:2020
País:España
Recursos:Universidad Rey Juan Carlos
Repositório:BURJC-Digital. Repositorio Institucional de la Universidad Rey Juan Carlos
OAI Identifier:oai:burjcdigital.urjc.es:10115/16911
Acesso em linha:http://hdl.handle.net/10115/16911
Access Level:Acesso embargado
Palavra-chave:5-hydroxymethylfurfural
Food processing contaminants
Cereal and insect bars
Functionalized mesostructured silica
SPE
HPLC-MS/MS
Ciencia y Tecnología de Alimentos
3309 Tecnología de Los Alimentos
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spelling Hydroxymethylfurfural determination in cereal and insect bars by high-performance liquid chromatography-mass spectrometry employing a functionalized mesostructured silica as sorbent in solid-phase extractionGonzález, LorenaMorante-Zarcero, SoniaPérez-Quintanilla, DamiánSierra, Isabel5-hydroxymethylfurfuralFood processing contaminantsCereal and insect barsFunctionalized mesostructured silicaSPEHPLC-MS/MSCiencia y Tecnología de Alimentos3309 Tecnología de Los AlimentosIn this work a new method for the determination of 5-hydroxymethylfurfural (HMF) in cereal and insect bars has been developed and validated. The method consisted of a solid-liquid extraction (SLE) followed by a solid phase extraction (SPE), employing functionalized mesostructured silica as sorbent, and prior to high-performance liquid chromatography coupled to mass spectrometry analysis (HPLC-MS/MS). Mesostructured silica with a large pore (SBA-15-LP) functionalized with aminopropyl- groups (SBA-15-LP-NH2), octyl- groups (SBA-15-LP-C8) and bifunctionalized with both organic ligands (SBA-15-LP-C8-NH2) were prepared, characterized and tested for this purpose. The optimal conditions showed that the best extraction solvent was water acidified with HCl (pH 1.0) and the best material for SPE was SBA-15-LP-NH2 (recoveries near 100%). Results were compared with other analogous commercial sorbent (Discovery® DSC-NH2), evaluated under similar conditions, and SBA-15-LP-NH2 sorbent showed better recoveries than the commercial one (62 ± 1%). developed method was validated and good detection and quantification limits (MDL: 11 μg kg-1and MQL: 38 μg kg-1), good precision in terms of repeatability and within-laboratory reproducibility (RSD < 8%) and good accuracy (recoveries between 99-102%) were obtained. The method was successfully applied to the determination of HMF in different samples of cereals and insect bars. In all the samples analysed, high concentrations of HMF (ranging from 336 to 962 mg kg-1) have been found.Elsevier202020202020info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10115/16911reponame:BURJC-Digital. Repositorio Institucional de la Universidad Rey Juan Carlosinstname:Universidad Rey Juan CarlosInglésproject S2018/BAA-4393, AVANSECAL-II-CMAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/embargoedAccessoai:burjcdigital.urjc.es:10115/169112026-06-24T12:48:17Z
dc.title.none.fl_str_mv Hydroxymethylfurfural determination in cereal and insect bars by high-performance liquid chromatography-mass spectrometry employing a functionalized mesostructured silica as sorbent in solid-phase extraction
title Hydroxymethylfurfural determination in cereal and insect bars by high-performance liquid chromatography-mass spectrometry employing a functionalized mesostructured silica as sorbent in solid-phase extraction
spellingShingle Hydroxymethylfurfural determination in cereal and insect bars by high-performance liquid chromatography-mass spectrometry employing a functionalized mesostructured silica as sorbent in solid-phase extraction
González, Lorena
5-hydroxymethylfurfural
Food processing contaminants
Cereal and insect bars
Functionalized mesostructured silica
SPE
HPLC-MS/MS
Ciencia y Tecnología de Alimentos
3309 Tecnología de Los Alimentos
title_short Hydroxymethylfurfural determination in cereal and insect bars by high-performance liquid chromatography-mass spectrometry employing a functionalized mesostructured silica as sorbent in solid-phase extraction
title_full Hydroxymethylfurfural determination in cereal and insect bars by high-performance liquid chromatography-mass spectrometry employing a functionalized mesostructured silica as sorbent in solid-phase extraction
title_fullStr Hydroxymethylfurfural determination in cereal and insect bars by high-performance liquid chromatography-mass spectrometry employing a functionalized mesostructured silica as sorbent in solid-phase extraction
title_full_unstemmed Hydroxymethylfurfural determination in cereal and insect bars by high-performance liquid chromatography-mass spectrometry employing a functionalized mesostructured silica as sorbent in solid-phase extraction
title_sort Hydroxymethylfurfural determination in cereal and insect bars by high-performance liquid chromatography-mass spectrometry employing a functionalized mesostructured silica as sorbent in solid-phase extraction
dc.creator.none.fl_str_mv González, Lorena
Morante-Zarcero, Sonia
Pérez-Quintanilla, Damián
Sierra, Isabel
author González, Lorena
author_facet González, Lorena
Morante-Zarcero, Sonia
Pérez-Quintanilla, Damián
Sierra, Isabel
author_role author
author2 Morante-Zarcero, Sonia
Pérez-Quintanilla, Damián
Sierra, Isabel
author2_role author
author
author
dc.subject.none.fl_str_mv 5-hydroxymethylfurfural
Food processing contaminants
Cereal and insect bars
Functionalized mesostructured silica
SPE
HPLC-MS/MS
Ciencia y Tecnología de Alimentos
3309 Tecnología de Los Alimentos
topic 5-hydroxymethylfurfural
Food processing contaminants
Cereal and insect bars
Functionalized mesostructured silica
SPE
HPLC-MS/MS
Ciencia y Tecnología de Alimentos
3309 Tecnología de Los Alimentos
description In this work a new method for the determination of 5-hydroxymethylfurfural (HMF) in cereal and insect bars has been developed and validated. The method consisted of a solid-liquid extraction (SLE) followed by a solid phase extraction (SPE), employing functionalized mesostructured silica as sorbent, and prior to high-performance liquid chromatography coupled to mass spectrometry analysis (HPLC-MS/MS). Mesostructured silica with a large pore (SBA-15-LP) functionalized with aminopropyl- groups (SBA-15-LP-NH2), octyl- groups (SBA-15-LP-C8) and bifunctionalized with both organic ligands (SBA-15-LP-C8-NH2) were prepared, characterized and tested for this purpose. The optimal conditions showed that the best extraction solvent was water acidified with HCl (pH 1.0) and the best material for SPE was SBA-15-LP-NH2 (recoveries near 100%). Results were compared with other analogous commercial sorbent (Discovery® DSC-NH2), evaluated under similar conditions, and SBA-15-LP-NH2 sorbent showed better recoveries than the commercial one (62 ± 1%). developed method was validated and good detection and quantification limits (MDL: 11 μg kg-1and MQL: 38 μg kg-1), good precision in terms of repeatability and within-laboratory reproducibility (RSD < 8%) and good accuracy (recoveries between 99-102%) were obtained. The method was successfully applied to the determination of HMF in different samples of cereals and insect bars. In all the samples analysed, high concentrations of HMF (ranging from 336 to 962 mg kg-1) have been found.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020
2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10115/16911
url http://hdl.handle.net/10115/16911
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv project S2018/BAA-4393, AVANSECAL-II-CM
dc.rights.none.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/embargoedAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv embargoedAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:BURJC-Digital. Repositorio Institucional de la Universidad Rey Juan Carlos
instname:Universidad Rey Juan Carlos
instname_str Universidad Rey Juan Carlos
reponame_str BURJC-Digital. Repositorio Institucional de la Universidad Rey Juan Carlos
collection BURJC-Digital. Repositorio Institucional de la Universidad Rey Juan Carlos
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.81155

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