The EULAR points to consider regarding the development of criterio for the assessment of the diseaseactivity inadult-onsetStill´s disease

Objectives: This study aims to formulate European Alliance of Associations for Rheumatology (EULAR) points to consider (PtCs) regarding the development of criteria for the assessment of the disease activity in adult-onset Still´s disease (AOSD). Methods: The Task Force consisted of 23 members from 7...

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Autores: Ruscitti, Piero, Stamm, Tanja, Ritschl, Valentin, Mitrovic, Stéphane, Girard Guyonvarc´´h, Charlotte, Alexanderson, Helene, Barten, Birgit, Bostrom, Carina, Fell, Dorothea, Gattorno, Marco, Guillemin, Francis, Körner, Melanie, Krusche, Martin, Llorca Díaz, Francisco Javier|||0000-0001-8569-861X, Quartier, Pierre, Ravelli, Angelo, Rosine, Nicolas, Wieczorek, Maud, Wilhelmer, Tanita Christina, González-Gay Mantecón, Miguel Ángel
Tipo de recurso: artículo
Fecha de publicación:2025
País:España
Institución:Universidad de Cantabria (UC)
Repositorio:UCrea Repositorio Abierto de la Universidad de Cantabria
Idioma:inglés
OAI Identifier:oai:repositorio.unican.es:10902/39149
Acceso en línea:https://hdl.handle.net/10902/39149
Access Level:acceso abierto
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spelling The EULAR points to consider regarding the development of criterio for the assessment of the diseaseactivity inadult-onsetStill´s diseaseRuscitti, PieroStamm, TanjaRitschl, ValentinMitrovic, StéphaneGirard Guyonvarc´´h, CharlotteAlexanderson, HeleneBarten, BirgitBostrom, CarinaFell, DorotheaGattorno, MarcoGuillemin, FrancisKörner, MelanieKrusche, MartinLlorca Díaz, Francisco Javier|||0000-0001-8569-861XQuartier, PierreRavelli, AngeloRosine, NicolasWieczorek, MaudWilhelmer, Tanita ChristinaGonzález-Gay Mantecón, Miguel ÁngelObjectives: This study aims to formulate European Alliance of Associations for Rheumatology (EULAR) points to consider (PtCs) regarding the development of criteria for the assessment of the disease activity in adult-onset Still´s disease (AOSD). Methods: The Task Force consisted of 23 members from 7 different European countries. A systematic literature review and a 3-round Delphi exercise involving European Experts were conducted to support the formulation of overarching principles and PtCs. Results: Based on retrieved evidence and Experts? opinions, results of Delphi Rounds, and discussions, 3 overarching principles and 11 PtCs were developed. The Task Force agreed on the importance of an appropriate definition for the disease activity in AOSD to be valid, reliable, and easily transferable in a clinical setting. The development of specific criteria for the assessment of disease activity should include a precise definition of the clinical features that could better describe the patient condition. A clear definition of disease activity would help clinicians to adjust therapy and to identify refractory patients. A validated assessment of the disease activity is important to establish specifically designed and powered studies for comprehensive management of patients with AOSD. A uniform and reproducible definition of remission may facilitate the inclusion of a new therapeutic target into daily practice and clinical trials. Conclusions: The EULAR PtCs were produced regarding the development of criteria for the assessment of the disease activity in AOSD, to provide the basis for a clinical tool to be readily, reliably, and easily applied in clinical settings in order to improve patient management.Elsevier B.V.Universidad de Cantabria20252025-01-01journal articlehttp://purl.org/coar/resource_type/c_6501NAhttp://purl.org/coar/version/c_be7fb7dd8ff6fe43info:eu-repo/semantics/articlehttps://hdl.handle.net/10902/39149EULAR Rheumatology Open, 2025, 0, 1-9reponame:UCrea Repositorio Abierto de la Universidad de Cantabriainstname:Universidad de Cantabria (UC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:repositorio.unican.es:10902/391492026-06-02T12:39:31Z
dc.title.none.fl_str_mv The EULAR points to consider regarding the development of criterio for the assessment of the diseaseactivity inadult-onsetStill´s disease
title The EULAR points to consider regarding the development of criterio for the assessment of the diseaseactivity inadult-onsetStill´s disease
spellingShingle The EULAR points to consider regarding the development of criterio for the assessment of the diseaseactivity inadult-onsetStill´s disease
Ruscitti, Piero
title_short The EULAR points to consider regarding the development of criterio for the assessment of the diseaseactivity inadult-onsetStill´s disease
title_full The EULAR points to consider regarding the development of criterio for the assessment of the diseaseactivity inadult-onsetStill´s disease
title_fullStr The EULAR points to consider regarding the development of criterio for the assessment of the diseaseactivity inadult-onsetStill´s disease
title_full_unstemmed The EULAR points to consider regarding the development of criterio for the assessment of the diseaseactivity inadult-onsetStill´s disease
title_sort The EULAR points to consider regarding the development of criterio for the assessment of the diseaseactivity inadult-onsetStill´s disease
dc.creator.none.fl_str_mv Ruscitti, Piero
Stamm, Tanja
Ritschl, Valentin
Mitrovic, Stéphane
Girard Guyonvarc´´h, Charlotte
Alexanderson, Helene
Barten, Birgit
Bostrom, Carina
Fell, Dorothea
Gattorno, Marco
Guillemin, Francis
Körner, Melanie
Krusche, Martin
Llorca Díaz, Francisco Javier|||0000-0001-8569-861X
Quartier, Pierre
Ravelli, Angelo
Rosine, Nicolas
Wieczorek, Maud
Wilhelmer, Tanita Christina
González-Gay Mantecón, Miguel Ángel
author Ruscitti, Piero
author_facet Ruscitti, Piero
Stamm, Tanja
Ritschl, Valentin
Mitrovic, Stéphane
Girard Guyonvarc´´h, Charlotte
Alexanderson, Helene
Barten, Birgit
Bostrom, Carina
Fell, Dorothea
Gattorno, Marco
Guillemin, Francis
Körner, Melanie
Krusche, Martin
Llorca Díaz, Francisco Javier|||0000-0001-8569-861X
Quartier, Pierre
Ravelli, Angelo
Rosine, Nicolas
Wieczorek, Maud
Wilhelmer, Tanita Christina
González-Gay Mantecón, Miguel Ángel
author_role author
author2 Stamm, Tanja
Ritschl, Valentin
Mitrovic, Stéphane
Girard Guyonvarc´´h, Charlotte
Alexanderson, Helene
Barten, Birgit
Bostrom, Carina
Fell, Dorothea
Gattorno, Marco
Guillemin, Francis
Körner, Melanie
Krusche, Martin
Llorca Díaz, Francisco Javier|||0000-0001-8569-861X
Quartier, Pierre
Ravelli, Angelo
Rosine, Nicolas
Wieczorek, Maud
Wilhelmer, Tanita Christina
González-Gay Mantecón, Miguel Ángel
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidad de Cantabria
description Objectives: This study aims to formulate European Alliance of Associations for Rheumatology (EULAR) points to consider (PtCs) regarding the development of criteria for the assessment of the disease activity in adult-onset Still´s disease (AOSD). Methods: The Task Force consisted of 23 members from 7 different European countries. A systematic literature review and a 3-round Delphi exercise involving European Experts were conducted to support the formulation of overarching principles and PtCs. Results: Based on retrieved evidence and Experts? opinions, results of Delphi Rounds, and discussions, 3 overarching principles and 11 PtCs were developed. The Task Force agreed on the importance of an appropriate definition for the disease activity in AOSD to be valid, reliable, and easily transferable in a clinical setting. The development of specific criteria for the assessment of disease activity should include a precise definition of the clinical features that could better describe the patient condition. A clear definition of disease activity would help clinicians to adjust therapy and to identify refractory patients. A validated assessment of the disease activity is important to establish specifically designed and powered studies for comprehensive management of patients with AOSD. A uniform and reproducible definition of remission may facilitate the inclusion of a new therapeutic target into daily practice and clinical trials. Conclusions: The EULAR PtCs were produced regarding the development of criteria for the assessment of the disease activity in AOSD, to provide the basis for a clinical tool to be readily, reliably, and easily applied in clinical settings in order to improve patient management.
publishDate 2025
dc.date.none.fl_str_mv 2025
2025-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
NA
http://purl.org/coar/version/c_be7fb7dd8ff6fe43
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/10902/39149
url https://hdl.handle.net/10902/39149
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv EULAR Rheumatology Open, 2025, 0, 1-9
reponame:UCrea Repositorio Abierto de la Universidad de Cantabria
instname:Universidad de Cantabria (UC)
instname_str Universidad de Cantabria (UC)
reponame_str UCrea Repositorio Abierto de la Universidad de Cantabria
collection UCrea Repositorio Abierto de la Universidad de Cantabria
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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