Opportunities and limits of combining microbiome and genome data for complex trait prediction

[Background]: Analysis and prediction of complex traits using microbiome data combined with host genomic information is a topic of utmost interest. However, numerous questions remain to be answered: how useful can the microbiome be for complex trait prediction? Are estimates of microbiability reliab...

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Detalles Bibliográficos
Autores: Pérez-Enciso, Miguel, Zingaretti, Laura M., Ramayo-Caldas, Yuliaxis, Campos, Gustavo de los
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/253919
Acceso en línea:http://hdl.handle.net/10261/253919
Access Level:acceso abierto
Descripción
Sumario:[Background]: Analysis and prediction of complex traits using microbiome data combined with host genomic information is a topic of utmost interest. However, numerous questions remain to be answered: how useful can the microbiome be for complex trait prediction? Are estimates of microbiability reliable? Can the underlying biological links between the host’s genome, microbiome, and phenome be recovered?