Estudio de la frecuencia, distribución y rendimiento diagnóstico en las lesiones neoplásicas sincrónicas del carcinoma colo-rectal

ABSTRACT To analyse the frequency, characteristics and diagnosis of synchronic neoplastic lesions in colorectal cancer. A review was carried out of 384 colorectal cancers, diagnosed through complete colonoscopy and resected. The synchronic cancers and the characteristics of the adenomas were determi...

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Autores: Borda-Martin, A. (Ana)|||/items/646a68f2-90f2-4d1e-8538-07815f26eac2, Martinez-Peñuela, J.M. (J.M.)|||/items/92cff34e-5fcc-4acc-a480-045258606ba5, Prieto-Martínez, C. (Carlos)|||/items/756bf37c-71ea-42b6-826d-f8f644906d56, Muñoz-Navas, M. (Miguel)|||/items/8c9e2db8-7dea-4686-9c8a-3bd4eeff584b, Carretero-Ribón, C. (Cristina)|||/items/37f2d58e-655b-4c90-9b71-3df3c5034300, Borda-Celaya, F. (F.)|||/items/0f599ed5-d64f-4d8b-b72a-e7fe40158ec2
Tipo de recurso: artículo
Fecha de publicación:2008
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:español
OAI Identifier:oai:dadun.unav.edu:10171/22579
Acceso en línea:https://hdl.handle.net/10171/22579
Access Level:acceso abierto
Palabra clave:Colorectal cancer
Synchronic lesions
Adenomas
Anatomía patológica
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spelling Estudio de la frecuencia, distribución y rendimiento diagnóstico en las lesiones neoplásicas sincrónicas del carcinoma colo-rectalStudy of frequency, distribution and diagnostic performance in synchronic neoplastic lesions of colorectal carcinomaBorda-Martin, A. (Ana)|||/items/646a68f2-90f2-4d1e-8538-07815f26eac2Martinez-Peñuela, J.M. (J.M.)|||/items/92cff34e-5fcc-4acc-a480-045258606ba5Prieto-Martínez, C. (Carlos)|||/items/756bf37c-71ea-42b6-826d-f8f644906d56Muñoz-Navas, M. (Miguel)|||/items/8c9e2db8-7dea-4686-9c8a-3bd4eeff584bCarretero-Ribón, C. (Cristina)|||/items/37f2d58e-655b-4c90-9b71-3df3c5034300Borda-Celaya, F. (F.)|||/items/0f599ed5-d64f-4d8b-b72a-e7fe40158ec2Colorectal cancerSynchronic lesionsAdenomasAnatomía patológicaABSTRACT To analyse the frequency, characteristics and diagnosis of synchronic neoplastic lesions in colorectal cancer. A review was carried out of 384 colorectal cancers, diagnosed through complete colonoscopy and resected. The synchronic cancers and the characteristics of the adenomas were determined: number, size, histological type, dysplasia, as well as their localisation in the colon and with respect to the carcinoma. Twenty-eight synchronic cancers were found (7.3% of the total); 8 developed tumours and 20 malignant polyps. In 54.4% of the cases there was a synchronic adenoma. In patients with synchronic lesions, 43% showed an advanced adenoma. Twenty percent of the synchronic polyps found were proximal to the splenic flexure; 41% were distal and 38% had both localisations. Fifty-nine point one percent of the patients had some adenoma proximal to the cancer, with criteria of advanced adenoma in 13.9%. The distribution of the adenomas was more uniformly spread in the cancers with a proximal localisation (p = 0.038). Seventeen percent of the distal cancers presented synchronic lesions with a proximal colon localisation exclusively. Partial endoscopies would diagnose the distal cancers, but would omit a synchronic adenoma in 42.3% of the sigmoidoscopies and 40% of the short colonoscopies. High rates of carcinoma and synchronic adenomas were registered. We underline the high index of advanced adenomas and the frequency of synchronic lesions proximal to the cancer, which is why incomplete colonoscopies, although allowing the diagnosis of the distal cancer, omit a high percentage of synchronic adenomas, including advanced lesions. All of this confirms the need to perform a complete pre- , intra- and post operational colonoscopy in resectable colorectal cancer.Gobierno de Navarra. Departamento de SaludDadun. Depósito Académico Digital Universidad de Navarra20122012-06-1620082008-01-0120082008-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10171/22579reponame:Dadun. Depósito Académico Digital de la Universidad de Navarrainstname:Universidad de NavarraEspañolspaopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:dadun.unav.edu:10171/225792026-06-21T12:47:57Z
dc.title.none.fl_str_mv Estudio de la frecuencia, distribución y rendimiento diagnóstico en las lesiones neoplásicas sincrónicas del carcinoma colo-rectal
Study of frequency, distribution and diagnostic performance in synchronic neoplastic lesions of colorectal carcinoma
title Estudio de la frecuencia, distribución y rendimiento diagnóstico en las lesiones neoplásicas sincrónicas del carcinoma colo-rectal
spellingShingle Estudio de la frecuencia, distribución y rendimiento diagnóstico en las lesiones neoplásicas sincrónicas del carcinoma colo-rectal
Borda-Martin, A. (Ana)|||/items/646a68f2-90f2-4d1e-8538-07815f26eac2
Colorectal cancer
Synchronic lesions
Adenomas
Anatomía patológica
title_short Estudio de la frecuencia, distribución y rendimiento diagnóstico en las lesiones neoplásicas sincrónicas del carcinoma colo-rectal
title_full Estudio de la frecuencia, distribución y rendimiento diagnóstico en las lesiones neoplásicas sincrónicas del carcinoma colo-rectal
title_fullStr Estudio de la frecuencia, distribución y rendimiento diagnóstico en las lesiones neoplásicas sincrónicas del carcinoma colo-rectal
title_full_unstemmed Estudio de la frecuencia, distribución y rendimiento diagnóstico en las lesiones neoplásicas sincrónicas del carcinoma colo-rectal
title_sort Estudio de la frecuencia, distribución y rendimiento diagnóstico en las lesiones neoplásicas sincrónicas del carcinoma colo-rectal
dc.creator.none.fl_str_mv Borda-Martin, A. (Ana)|||/items/646a68f2-90f2-4d1e-8538-07815f26eac2
Martinez-Peñuela, J.M. (J.M.)|||/items/92cff34e-5fcc-4acc-a480-045258606ba5
Prieto-Martínez, C. (Carlos)|||/items/756bf37c-71ea-42b6-826d-f8f644906d56
Muñoz-Navas, M. (Miguel)|||/items/8c9e2db8-7dea-4686-9c8a-3bd4eeff584b
Carretero-Ribón, C. (Cristina)|||/items/37f2d58e-655b-4c90-9b71-3df3c5034300
Borda-Celaya, F. (F.)|||/items/0f599ed5-d64f-4d8b-b72a-e7fe40158ec2
author Borda-Martin, A. (Ana)|||/items/646a68f2-90f2-4d1e-8538-07815f26eac2
author_facet Borda-Martin, A. (Ana)|||/items/646a68f2-90f2-4d1e-8538-07815f26eac2
Martinez-Peñuela, J.M. (J.M.)|||/items/92cff34e-5fcc-4acc-a480-045258606ba5
Prieto-Martínez, C. (Carlos)|||/items/756bf37c-71ea-42b6-826d-f8f644906d56
Muñoz-Navas, M. (Miguel)|||/items/8c9e2db8-7dea-4686-9c8a-3bd4eeff584b
Carretero-Ribón, C. (Cristina)|||/items/37f2d58e-655b-4c90-9b71-3df3c5034300
Borda-Celaya, F. (F.)|||/items/0f599ed5-d64f-4d8b-b72a-e7fe40158ec2
author_role author
author2 Martinez-Peñuela, J.M. (J.M.)|||/items/92cff34e-5fcc-4acc-a480-045258606ba5
Prieto-Martínez, C. (Carlos)|||/items/756bf37c-71ea-42b6-826d-f8f644906d56
Muñoz-Navas, M. (Miguel)|||/items/8c9e2db8-7dea-4686-9c8a-3bd4eeff584b
Carretero-Ribón, C. (Cristina)|||/items/37f2d58e-655b-4c90-9b71-3df3c5034300
Borda-Celaya, F. (F.)|||/items/0f599ed5-d64f-4d8b-b72a-e7fe40158ec2
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Dadun. Depósito Académico Digital Universidad de Navarra
dc.subject.none.fl_str_mv Colorectal cancer
Synchronic lesions
Adenomas
Anatomía patológica
topic Colorectal cancer
Synchronic lesions
Adenomas
Anatomía patológica
description ABSTRACT To analyse the frequency, characteristics and diagnosis of synchronic neoplastic lesions in colorectal cancer. A review was carried out of 384 colorectal cancers, diagnosed through complete colonoscopy and resected. The synchronic cancers and the characteristics of the adenomas were determined: number, size, histological type, dysplasia, as well as their localisation in the colon and with respect to the carcinoma. Twenty-eight synchronic cancers were found (7.3% of the total); 8 developed tumours and 20 malignant polyps. In 54.4% of the cases there was a synchronic adenoma. In patients with synchronic lesions, 43% showed an advanced adenoma. Twenty percent of the synchronic polyps found were proximal to the splenic flexure; 41% were distal and 38% had both localisations. Fifty-nine point one percent of the patients had some adenoma proximal to the cancer, with criteria of advanced adenoma in 13.9%. The distribution of the adenomas was more uniformly spread in the cancers with a proximal localisation (p = 0.038). Seventeen percent of the distal cancers presented synchronic lesions with a proximal colon localisation exclusively. Partial endoscopies would diagnose the distal cancers, but would omit a synchronic adenoma in 42.3% of the sigmoidoscopies and 40% of the short colonoscopies. High rates of carcinoma and synchronic adenomas were registered. We underline the high index of advanced adenomas and the frequency of synchronic lesions proximal to the cancer, which is why incomplete colonoscopies, although allowing the diagnosis of the distal cancer, omit a high percentage of synchronic adenomas, including advanced lesions. All of this confirms the need to perform a complete pre- , intra- and post operational colonoscopy in resectable colorectal cancer.
publishDate 2008
dc.date.none.fl_str_mv 2008
2008-01-01
2008
2008-01-01
2012
2012-06-16
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/10171/22579
url https://hdl.handle.net/10171/22579
dc.language.none.fl_str_mv Español
spa
language_invalid_str_mv Español
language spa
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Gobierno de Navarra. Departamento de Salud
publisher.none.fl_str_mv Gobierno de Navarra. Departamento de Salud
dc.source.none.fl_str_mv reponame:Dadun. Depósito Académico Digital de la Universidad de Navarra
instname:Universidad de Navarra
instname_str Universidad de Navarra
reponame_str Dadun. Depósito Académico Digital de la Universidad de Navarra
collection Dadun. Depósito Académico Digital de la Universidad de Navarra
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