Nanoscale Wetting of Single Viruses

The epidemic spread of many viral infections is mediated by the environmental conditions and influenced by the ambient humidity. Single virus particles have been mainly visualized by atomic force microscopy (AFM) in liquid conditions, where the effect of the relative humidity on virus topography and...

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Detalles Bibliográficos
Autores: Calò, Annalisa, Eleta-Lopez, Aitziber|||0000-0002-2498-1857, Ondarçuhu, Thierry|||0000-0001-7657-5271, Verdaguer Prats, Albert|||0000-0002-4855-821X, Bittner, Alexander M.
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:264932
Acceso en línea:https://ddd.uab.cat/record/264932
https://dx.doi.org/urn:doi:10.3390/molecules26175184
Access Level:acceso abierto
Palabra clave:Tobacco Mosaic Virus (TMV)
Nanoscale wetting
Multifrequency AFM
Force reconstruction
Amplitude-modulation AM-AFM
Descripción
Sumario:The epidemic spread of many viral infections is mediated by the environmental conditions and influenced by the ambient humidity. Single virus particles have been mainly visualized by atomic force microscopy (AFM) in liquid conditions, where the effect of the relative humidity on virus topography and surface cannot be systematically assessed. In this work, we employed multi-frequency AFM, simultaneously with standard topography imaging, to study the nanoscale wetting of individual Tobacco Mosaic virions (TMV) from ambient relative humidity to water condensation (RH.