Measuring apoptosis at the single cell level

The use of live cell microscopy has made a number of contributions to the study of apoptosis. Many of the tools and techniques are available that allow us to image the key events that occur during cell death including mitochondrial outer membrane permeabilization, mitochondrial transmembrane potenti...

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Detalles Bibliográficos
Autores: Bouchier-Hayes, Lisa, Muñoz Pinedo, Cristina, Connell, Samuel, Green, Douglas R.
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2008
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/126415
Acceso en línea:https://hdl.handle.net/2445/126415
Access Level:acceso abierto
Palabra clave:Apoptosi
Microscòpia confocal
Apoptosis
Confocal microscopy
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spelling Measuring apoptosis at the single cell levelBouchier-Hayes, LisaMuñoz Pinedo, CristinaConnell, SamuelGreen, Douglas R.ApoptosiMicroscòpia confocalApoptosisConfocal microscopyThe use of live cell microscopy has made a number of contributions to the study of apoptosis. Many of the tools and techniques are available that allow us to image the key events that occur during cell death including mitochondrial outer membrane permeabilization, mitochondrial transmembrane potential changes, translocation of Bcl-2 family members, caspase activation, phosphatidylserine flip and plasma membrane rupture. We discuss these techniques here and highlight the advantages and drawbacks of using such approaches to study apoptosis. (C) 2007 Elsevier Inc. All rights reserved.Elsevier Science2008info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfhttps://hdl.handle.net/2445/126415Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésVersió postprint del document publicat a: https://doi.org/10.1016/j.ymeth.2007.11.007Methods, 2008, vol. 44, num. 3, p. 222-228https://doi.org/10.1016/j.ymeth.2007.11.007(c) Elsevier, 2008info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1264152026-05-27T06:46:51Z
dc.title.none.fl_str_mv Measuring apoptosis at the single cell level
title Measuring apoptosis at the single cell level
spellingShingle Measuring apoptosis at the single cell level
Bouchier-Hayes, Lisa
Apoptosi
Microscòpia confocal
Apoptosis
Confocal microscopy
title_short Measuring apoptosis at the single cell level
title_full Measuring apoptosis at the single cell level
title_fullStr Measuring apoptosis at the single cell level
title_full_unstemmed Measuring apoptosis at the single cell level
title_sort Measuring apoptosis at the single cell level
dc.creator.none.fl_str_mv Bouchier-Hayes, Lisa
Muñoz Pinedo, Cristina
Connell, Samuel
Green, Douglas R.
author Bouchier-Hayes, Lisa
author_facet Bouchier-Hayes, Lisa
Muñoz Pinedo, Cristina
Connell, Samuel
Green, Douglas R.
author_role author
author2 Muñoz Pinedo, Cristina
Connell, Samuel
Green, Douglas R.
author2_role author
author
author
dc.subject.none.fl_str_mv Apoptosi
Microscòpia confocal
Apoptosis
Confocal microscopy
topic Apoptosi
Microscòpia confocal
Apoptosis
Confocal microscopy
description The use of live cell microscopy has made a number of contributions to the study of apoptosis. Many of the tools and techniques are available that allow us to image the key events that occur during cell death including mitochondrial outer membrane permeabilization, mitochondrial transmembrane potential changes, translocation of Bcl-2 family members, caspase activation, phosphatidylserine flip and plasma membrane rupture. We discuss these techniques here and highlight the advantages and drawbacks of using such approaches to study apoptosis. (C) 2007 Elsevier Inc. All rights reserved.
publishDate 2008
dc.date.none.fl_str_mv 2008
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/126415
url https://hdl.handle.net/2445/126415
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Versió postprint del document publicat a: https://doi.org/10.1016/j.ymeth.2007.11.007
Methods, 2008, vol. 44, num. 3, p. 222-228
https://doi.org/10.1016/j.ymeth.2007.11.007
dc.rights.none.fl_str_mv (c) Elsevier, 2008
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Elsevier, 2008
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.301629

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