Validation of the Spanish Version of the PURE-4 Questionnaire for the Early Detection of Psoriatic Arthritis in Psoriatic Patients

Background and objective: Psoriasis often precedes the onset of psoriatic arthritis (PsA), so dermatologists often face the challenge of early identifying signs of PsA in patients with psoriasis. Our aim was to validate the Spanish version of the PURE-4 questionnaire as a screening tool for PsA, eva...

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Autores: Belinchón-Romero, I, López-Ferrer, A, Farrés, MFI, Rivera-Díaz, R, Vidal-Sarro, D, Fernández-Freire, LR, de la Cueva-dobao, P, Santos-Juanes, J, Rocamora-Durán, V, Martín-Vázquez, V, Gómez-Labradror, L, Queiro-Silva, R
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Instituto de Investigación Biomédica y Sanitaria de Alicante (ISABIAL)
Repositorio:r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
OAI Identifier:oai:isabial.fundanetsuite.com:p10290
Acceso en línea:https://isabial.portalinvestigacion.com/publicaciones10290
https://www.sciencedirect.com/science/article/pii/S0001731024004319?via%3Dihub
Access Level:acceso abierto
Palabra clave:Psoriasis
Psoriatic arthritis
Screening
PURE-4
Referral
Diagnostic performance
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spelling Validation of the Spanish Version of the PURE-4 Questionnaire for the Early Detection of Psoriatic Arthritis in Psoriatic PatientsBelinchón-Romero, ILópez-Ferrer, AFarrés, MFIRivera-Díaz, RVidal-Sarro, DFernández-Freire, LRde la Cueva-dobao, PSantos-Juanes, JRocamora-Durán, VMartín-Vázquez, VGómez-Labradror, LQueiro-Silva, RPsoriasisPsoriatic arthritisScreeningPURE-4ReferralDiagnostic performanceBackground and objective: Psoriasis often precedes the onset of psoriatic arthritis (PsA), so dermatologists often face the challenge of early identifying signs of PsA in patients with psoriasis. Our aim was to validate the Spanish version of the PURE-4 questionnaire as a screening tool for PsA, evaluate its performance in terms of sensitivity, specificity, feasibility, reliability, and build validity. Methods: This was a cross-sectional, observational, multicenter trial of adult patients with psoriasis. Initially, patients were assessed by a dermatologist and completed 2 self-administered versions (in print and online) of the PURE-4 questionnaire. Afterwards, the rheumatologist, blinded to the PURE-4 results, assessed the presence/absence of PsA, being the reference to determine the performance of the PURE-4 questionnaire. Results: A total of 268 patients were included (115 [42.9%] women; mean age, 47.1 +/- 12.6). The prevalence of PsA according to rheumatologist diagnosis was 12.7% (34 patients). The mean PURE-4 score for patients with psoriasis diagnosed with PsA was 2.3 +/- 1.1, and 1.3 +/- 1.3 for patients without PsA ( P < .001). The cutoff value > 2 demonstrated the best performance for detecting PsA, with a negative predictive value of 95.1% (95% confidence interval, 90.3-97.6). Conclusions: The PURE-4 questionnaire demonstrated good performance in detecting PsA, with an optimal cutoff point > 2. This simple tool could facilitate early referral of patients to the rheumatology unit. (c) 2024 AEDV. Published by Elsevier Espana, S.L.U. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).ELSEVIER ESPANA2024info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://isabial.portalinvestigacion.com/publicaciones10290https://www.sciencedirect.com/science/article/pii/S0001731024004319?via%3DihubActas Dermo-SifiliograficasISSN: 00017310ISSNe: 15782190reponame:r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicanteinstname:Instituto de Investigación Biomédica y Sanitaria de Alicante (ISABIAL)Españolinfo:eu-repo/semantics/openAccessoai:isabial.fundanetsuite.com:p102902026-06-12T10:20:37Z
dc.title.none.fl_str_mv Validation of the Spanish Version of the PURE-4 Questionnaire for the Early Detection of Psoriatic Arthritis in Psoriatic Patients
title Validation of the Spanish Version of the PURE-4 Questionnaire for the Early Detection of Psoriatic Arthritis in Psoriatic Patients
spellingShingle Validation of the Spanish Version of the PURE-4 Questionnaire for the Early Detection of Psoriatic Arthritis in Psoriatic Patients
Belinchón-Romero, I
Psoriasis
Psoriatic arthritis
Screening
PURE-4
Referral
Diagnostic performance
title_short Validation of the Spanish Version of the PURE-4 Questionnaire for the Early Detection of Psoriatic Arthritis in Psoriatic Patients
title_full Validation of the Spanish Version of the PURE-4 Questionnaire for the Early Detection of Psoriatic Arthritis in Psoriatic Patients
title_fullStr Validation of the Spanish Version of the PURE-4 Questionnaire for the Early Detection of Psoriatic Arthritis in Psoriatic Patients
title_full_unstemmed Validation of the Spanish Version of the PURE-4 Questionnaire for the Early Detection of Psoriatic Arthritis in Psoriatic Patients
title_sort Validation of the Spanish Version of the PURE-4 Questionnaire for the Early Detection of Psoriatic Arthritis in Psoriatic Patients
dc.creator.none.fl_str_mv Belinchón-Romero, I
López-Ferrer, A
Farrés, MFI
Rivera-Díaz, R
Vidal-Sarro, D
Fernández-Freire, LR
de la Cueva-dobao, P
Santos-Juanes, J
Rocamora-Durán, V
Martín-Vázquez, V
Gómez-Labradror, L
Queiro-Silva, R
author Belinchón-Romero, I
author_facet Belinchón-Romero, I
López-Ferrer, A
Farrés, MFI
Rivera-Díaz, R
Vidal-Sarro, D
Fernández-Freire, LR
de la Cueva-dobao, P
Santos-Juanes, J
Rocamora-Durán, V
Martín-Vázquez, V
Gómez-Labradror, L
Queiro-Silva, R
author_role author
author2 López-Ferrer, A
Farrés, MFI
Rivera-Díaz, R
Vidal-Sarro, D
Fernández-Freire, LR
de la Cueva-dobao, P
Santos-Juanes, J
Rocamora-Durán, V
Martín-Vázquez, V
Gómez-Labradror, L
Queiro-Silva, R
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Psoriasis
Psoriatic arthritis
Screening
PURE-4
Referral
Diagnostic performance
topic Psoriasis
Psoriatic arthritis
Screening
PURE-4
Referral
Diagnostic performance
description Background and objective: Psoriasis often precedes the onset of psoriatic arthritis (PsA), so dermatologists often face the challenge of early identifying signs of PsA in patients with psoriasis. Our aim was to validate the Spanish version of the PURE-4 questionnaire as a screening tool for PsA, evaluate its performance in terms of sensitivity, specificity, feasibility, reliability, and build validity. Methods: This was a cross-sectional, observational, multicenter trial of adult patients with psoriasis. Initially, patients were assessed by a dermatologist and completed 2 self-administered versions (in print and online) of the PURE-4 questionnaire. Afterwards, the rheumatologist, blinded to the PURE-4 results, assessed the presence/absence of PsA, being the reference to determine the performance of the PURE-4 questionnaire. Results: A total of 268 patients were included (115 [42.9%] women; mean age, 47.1 +/- 12.6). The prevalence of PsA according to rheumatologist diagnosis was 12.7% (34 patients). The mean PURE-4 score for patients with psoriasis diagnosed with PsA was 2.3 +/- 1.1, and 1.3 +/- 1.3 for patients without PsA ( P < .001). The cutoff value > 2 demonstrated the best performance for detecting PsA, with a negative predictive value of 95.1% (95% confidence interval, 90.3-97.6). Conclusions: The PURE-4 questionnaire demonstrated good performance in detecting PsA, with an optimal cutoff point > 2. This simple tool could facilitate early referral of patients to the rheumatology unit. (c) 2024 AEDV. Published by Elsevier Espana, S.L.U. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
publishDate 2024
dc.date.none.fl_str_mv 2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://isabial.portalinvestigacion.com/publicaciones10290
https://www.sciencedirect.com/science/article/pii/S0001731024004319?via%3Dihub
url https://isabial.portalinvestigacion.com/publicaciones10290
https://www.sciencedirect.com/science/article/pii/S0001731024004319?via%3Dihub
dc.language.none.fl_str_mv Español
language_invalid_str_mv Español
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv ELSEVIER ESPANA
publisher.none.fl_str_mv ELSEVIER ESPANA
dc.source.none.fl_str_mv Actas Dermo-Sifiliograficas
ISSN: 00017310
ISSNe: 15782190
reponame:r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
instname:Instituto de Investigación Biomédica y Sanitaria de Alicante (ISABIAL)
instname_str Instituto de Investigación Biomédica y Sanitaria de Alicante (ISABIAL)
reponame_str r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
collection r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
repository.name.fl_str_mv
repository.mail.fl_str_mv
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