Evaluating the quality of real-world data on adherence to oral endocrine therapy in breast cancer patients: How real-world data?

Simple Summary: The objective of this study was to evaluate the validity of RWD-based adherence measurements obtained from accessible electronic health records in the Spanish national health system in all women diagnosed with breast cancer in the public healthcare system in Catalonia (Spain). Our re...

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Bibliographic Details
Authors: Navarro i Sabaté, Àurea, Font, Rebeca, Espinàs Piñol, Josep Alfons, Solà, Judit, Martínez Soler, Fina, Gil Gil, Miguel, Viñas, Gemma, Tibau Martorell, Ariadna, Borrell, Maria, Segui Palmer, Miguel Ángel, Margelí Vila, Mireia, Servitja, Sonia, Pérez Segura, Cristina, Domènech, M., Nava, Maria Ángeles, Marin, Mar, Gonzalez, Sergi, Borràs Andrés, Josep Maria
Format: article
Status:Published version
Publication Date:2025
Country:España
Institution:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repository:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:dnet:recercat____::846fbf2f5a5a3b411acda9177fca7c2e
Online Access:https://hdl.handle.net/2445/228591
Access Level:Open access
Keyword:Ressenyes sistemàtiques (Investigació mèdica)
Infermeria basada en l'evidència
Càncer de mama
Systematic reviews (Medical research)
Evidence-based nursing
Breast cancer
Description
Summary:Simple Summary: The objective of this study was to evaluate the validity of RWD-based adherence measurements obtained from accessible electronic health records in the Spanish national health system in all women diagnosed with breast cancer in the public healthcare system in Catalonia (Spain). Our results showed that nonadherence during the first year of treatment was around 11% in both cohorts, analysed using the RWD, and without significant differences between them. Furthermore, determinants associated with nonadherence (age and type of oral endocrine treatment) were similar in both approaches used. The results also show that it is fast and feasible to use RWD to identify individuals who are not refilling prescriptions as often as they should. In conclusion, the validity of the RWD method to estimate adherence has been confirmed and, at the same time, this method provides valuable evidence to help oncologists discuss adherence with their patients.

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