How diet and lifestyle can fine-tune gut microbiomes for healthy aging

Many physical, social, and psychological changes occur during aging that raise the risk of developing chronic diseases, frailty, and dependency. These changes adversely affect the gut microbiota, a phenomenon known as microbe-aging. Those microbiota alterations are, in turn, associated with the deve...

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Detalles Bibliográficos
Autores: Tamayo Belda, Miguel, Olivares, M., Ruas Madiedo, P., Margolles, A., Espín, J. C., Medina, I., Moreno Arribas, María Victoria, Canals, S., Mirasso, C. R., Ortín, S., Beltrán Sánchez, H., Palloni, A., Tomás-Barberán, F. A., Sanz, Y.
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/720411
Acceso en línea:http://hdl.handle.net/10486/720411
https://dx.doi.org/10.1146/annurev-food-072023-034458
Access Level:acceso abierto
Palabra clave:microbiota
microbiome
aging
diet
personalized nutrition
probiotics
Medicina
Descripción
Sumario:Many physical, social, and psychological changes occur during aging that raise the risk of developing chronic diseases, frailty, and dependency. These changes adversely affect the gut microbiota, a phenomenon known as microbe-aging. Those microbiota alterations are, in turn, associated with the development of age-related diseases. The gut microbiota is highly responsive to lifestyle and dietary changes, displaying a flexibility that also provides an actionable tool by which healthy aging can be promoted. This review covers, firstly, the main lifestyle and socioeconomic factors that modify the gut microbiota composition and function during healthy or unhealthy aging and, secondly, the advances being made in defining and promoting healthy aging, including microbiome-informed artificial intelligence tools, personalized dietary patterns, and food probiotic systems