Anatomical Site, Typing, Virulence Gene Profiling, Antimicrobial Susceptibility and Resistance Genes of Streptococcus suis Isolates Recovered from Pigs in Spain

Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).

Detalles Bibliográficos
Autores: Petrocchi Rilo, Máximo, Martínez Martínez, Sonia, Aguarón Turrientes, Álvaro, Roca Martínez, Elisabet, García Iglesias, María José, Pérez Fernández, Esther, González Fernández, Alba, Herencia Lagunar, Elena, Gutiérrez Martín, César Bernardo
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Universidad Rey Juan Carlos
Repositorio:BULERIA. Repositorio Institucional de la Universidad de León
OAI Identifier:oai:buleria.unileon.es:10612/18838
Acceso en línea:https://www.mdpi.com/2079-6382/10/6/707
https://hdl.handle.net/10612/18838
Access Level:acceso abierto
Palabra clave:Sanidad animal
Streptococcus suis
Swine
Typing
Virulence genes
Antimicrobial susceptibility
Resistance genes
3109 Ciencias Veterinarias
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network_name_str España
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spelling Anatomical Site, Typing, Virulence Gene Profiling, Antimicrobial Susceptibility and Resistance Genes of Streptococcus suis Isolates Recovered from Pigs in SpainPetrocchi Rilo, MáximoMartínez Martínez, SoniaAguarón Turrientes, ÁlvaroRoca Martínez, ElisabetGarcía Iglesias, María JoséPérez Fernández, EstherGonzález Fernández, AlbaHerencia Lagunar, ElenaGutiérrez Martín, César BernardoSanidad animalStreptococcus suisSwineTypingVirulence genesAntimicrobial susceptibilityResistance genes3109 Ciencias VeterinariasCopyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).[EN] A set of 207 Streptococcus suis isolates were collected from ten autonomous communities from Spain in 2019 to 2020 from pigs with meningitis, pneumonic lungs, arthritic joints or other swollen viscera, to a lesser extent. Thirteen capsular types were detected being the most prevalent serotype 2 (21.7%), followed by serotypes 1 (21.3%), 9 (19.3%) and 3 (6.3%). Serotypes 2 and 9 were recovered mainly from the central nervous system (CNS), while serotype 1 was isolated mostly from swollen joints and serotype 3 from the lungs. Twenty-five isolates (12.1%) could not be typed. The most prevalent pathotype was epf + mrp + sly + luxS (49 isolates, 23.8%), and it was related mainly to serotypes 1 and 2. Serotypes 1–3 and 9 were significantly associated with anatomical sites of isolation and virulence factors, serotype 9 (CNS) and serotypes 3 and 9 (lungs) being associated with virulence profiles without the epf gene. S. suis isolates showed globally high antimicrobial resistances, but ampicillin followed by spectinomycin and tiamulin resulted in the highest activities, while the greatest resistances were detected for sulphadimethoxine, tetracyclines, neomycin, clindamycin and macrolides. A total of 87.4% isolates were positive to the tetO gene, 62.4% to the ermB gene and 25.2% to the fexA gene, while 14.6% were positive to all three genes simultaneously. A significative association between isolate resistances to tetracyclines and macrolides and the resistance genes tested was established, except for phenicol resistance and the fexA gene. A set of 14 multiresistance patterns were obtained according to the number of antimicrobials to which the isolates were resistant, the resistances to 12 or more agents being the most prevalent ones. A remarkable amount of multiresistance profiles could be seen among the S. suis serotype 9 isolates.SIWe acknowledge Laboratorios SYVA for the assignment of the 207 S. suis isolates because they are property of this Spanish laboratory.This research was funded by the contract project called “Obtención y caracterización de aislados de Hameophilus parasuis y Streptococcus suis en gando porcino de Castilla y León para la realización de una autovacuna eficaz” (C-309), financed by Laboratorios SYVA S.A.U., León. M.P.R. was a recipient of a contract grant from this Spanish laboratory.MDPISanidad AnimalFacultad de Veterinaria2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://www.mdpi.com/2079-6382/10/6/707https://hdl.handle.net/10612/18838reponame:BULERIA. Repositorio Institucional de la Universidad de Leóninstname:Universidad Rey Juan CarlosIngléshttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:buleria.unileon.es:10612/188382026-06-24T12:43:27Z
dc.title.none.fl_str_mv Anatomical Site, Typing, Virulence Gene Profiling, Antimicrobial Susceptibility and Resistance Genes of Streptococcus suis Isolates Recovered from Pigs in Spain
title Anatomical Site, Typing, Virulence Gene Profiling, Antimicrobial Susceptibility and Resistance Genes of Streptococcus suis Isolates Recovered from Pigs in Spain
spellingShingle Anatomical Site, Typing, Virulence Gene Profiling, Antimicrobial Susceptibility and Resistance Genes of Streptococcus suis Isolates Recovered from Pigs in Spain
Petrocchi Rilo, Máximo
Sanidad animal
Streptococcus suis
Swine
Typing
Virulence genes
Antimicrobial susceptibility
Resistance genes
3109 Ciencias Veterinarias
title_short Anatomical Site, Typing, Virulence Gene Profiling, Antimicrobial Susceptibility and Resistance Genes of Streptococcus suis Isolates Recovered from Pigs in Spain
title_full Anatomical Site, Typing, Virulence Gene Profiling, Antimicrobial Susceptibility and Resistance Genes of Streptococcus suis Isolates Recovered from Pigs in Spain
title_fullStr Anatomical Site, Typing, Virulence Gene Profiling, Antimicrobial Susceptibility and Resistance Genes of Streptococcus suis Isolates Recovered from Pigs in Spain
title_full_unstemmed Anatomical Site, Typing, Virulence Gene Profiling, Antimicrobial Susceptibility and Resistance Genes of Streptococcus suis Isolates Recovered from Pigs in Spain
title_sort Anatomical Site, Typing, Virulence Gene Profiling, Antimicrobial Susceptibility and Resistance Genes of Streptococcus suis Isolates Recovered from Pigs in Spain
dc.creator.none.fl_str_mv Petrocchi Rilo, Máximo
Martínez Martínez, Sonia
Aguarón Turrientes, Álvaro
Roca Martínez, Elisabet
García Iglesias, María José
Pérez Fernández, Esther
González Fernández, Alba
Herencia Lagunar, Elena
Gutiérrez Martín, César Bernardo
author Petrocchi Rilo, Máximo
author_facet Petrocchi Rilo, Máximo
Martínez Martínez, Sonia
Aguarón Turrientes, Álvaro
Roca Martínez, Elisabet
García Iglesias, María José
Pérez Fernández, Esther
González Fernández, Alba
Herencia Lagunar, Elena
Gutiérrez Martín, César Bernardo
author_role author
author2 Martínez Martínez, Sonia
Aguarón Turrientes, Álvaro
Roca Martínez, Elisabet
García Iglesias, María José
Pérez Fernández, Esther
González Fernández, Alba
Herencia Lagunar, Elena
Gutiérrez Martín, César Bernardo
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Sanidad Animal
Facultad de Veterinaria
dc.subject.none.fl_str_mv Sanidad animal
Streptococcus suis
Swine
Typing
Virulence genes
Antimicrobial susceptibility
Resistance genes
3109 Ciencias Veterinarias
topic Sanidad animal
Streptococcus suis
Swine
Typing
Virulence genes
Antimicrobial susceptibility
Resistance genes
3109 Ciencias Veterinarias
description Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://www.mdpi.com/2079-6382/10/6/707
https://hdl.handle.net/10612/18838
url https://www.mdpi.com/2079-6382/10/6/707
https://hdl.handle.net/10612/18838
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:BULERIA. Repositorio Institucional de la Universidad de León
instname:Universidad Rey Juan Carlos
instname_str Universidad Rey Juan Carlos
reponame_str BULERIA. Repositorio Institucional de la Universidad de León
collection BULERIA. Repositorio Institucional de la Universidad de León
repository.name.fl_str_mv
repository.mail.fl_str_mv
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