Time-sequenced transcriptomes of developing distal mouse limb buds: A comparative tissue layer analysis
[Background]: The development of the amniote limb has been an important model system to study patterning mechanisms and morphogenesis. For proper growth and patterning, it requires the interaction between the distal sub-apical mesenchyme and the apical ectodermal ridge (AER) that involve the separat...
| Autores: | , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2022 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/303002 |
| Acceso en línea: | http://hdl.handle.net/10261/303002 |
| Access Level: | acceso abierto |
| Palabra clave: | AER Hox genes Limb patterning Limb progenitors RNA-seq Signaling Transcriptome |
| Sumario: | [Background]: The development of the amniote limb has been an important model system to study patterning mechanisms and morphogenesis. For proper growth and patterning, it requires the interaction between the distal sub-apical mesenchyme and the apical ectodermal ridge (AER) that involve the separate implementation of coordinated and tissue-specific genetic programs. |
|---|